Clinical trials: Instability, Joint
Osteoarthritis, Knee, Arthritis, Rheumatoid
Evaluation of Medium Cross-linked Polyethylene With and Without Vitamin E for Total Knee Arthroplasty
Prospective, randomized, single-blind, multinational, long-term study for the evaluation of the clinical outcome, oxidation profile and wear analysis of medium cross-linked Polyethylene with and without Vitamin E for total knee…
- Conditions
- Osteoarthritis, Knee, Arthritis, Rheumatoid, Intra-Articular Fractures, Joint Instability
- Trial name
- VIKEP (NCT04618016)
- Testing
- UHMWPE with Vitamin E, UHMWPE without Vitamin E
- Where
- 8 sites in France, Germany
- Volunteers
- 605 people
- Sponsor
- Aesculap AG
Musculoskeletal Growth and Development
A Study on Associations Between Multidimensional Human Phenotypic Traits and Human Growth and Development
This observational study aims to investigate the associations between multidimensional human phenotypic characteristics and growth and developmental features.
- Trial name
- NCT07857798
- Testing
- Fingerprint Morphological Characteristics
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Chronic Ankle Instability, Ankle Sprain
Collagen Scaffold Bioaugmentation for ATFL Repair in Chronic Ankle Instability
This is a multicenter, randomized, controlled clinical trial comparing two surgical techniques for the treatment of chronic ankle instability (CAI).
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Joint Instability
- Trial name
- REAR (NCT07878312)
- Testing
- Arthroscopic Anterior Talofibular Ligament Repair, Internal Brace Augmentation, REGENETEN Bioinductive Collagen Scaffold
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Primary Knee Arthroplasty
ATTUNE® Revision- Complex Primary in Total Knee Arthroplasty Population
Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing…
- Trial name
- NCT03153449
- Testing
- ATTUNE Revision Knee System in Total Knee Arthroplasty
- Where
- 34 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- DePuy Orthopaedics
Hypermobility Spectrum Disorder
Whole-Body Vibration and Postural Stability in Painful HSD
This randomized controlled trial aims to investigate the effects of adding whole-body vibration training to a conventional exercise program on postural stability and pain in painful women with hypermobility spectrum disorder.
- Trial name
- NCT07830589
- Testing
- Conventional Exercise Program, Whole-Body Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gökalp Arif Utkugün
Habitual Knuckle Cracking
Stabilization Exercises for Young Adults With Habitual Knuckle Cracking
Habitual knuckle cracking is a widespread behavior caused by intra-articular pressure changes and gas release in synovial joints; however, its long-term effects on hand sensorimotor function, joint laxity, and overall…
- Trial name
- NCT07815717
- Testing
- Stabilization Exercise Program
- Volunteers
- 42 people
- Sponsor
- Borna Farhoomand
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Lipedema, Hypermobility, Joint
Joint Hypermobility and Associated Factors in Patients With Lipedema
The aim of this observational study is to determine the prevalence of joint hypermobility in female patients with lipedema compared to healthy volunteers.
- Trial name
- LIP-HYP (NCT07808242)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Anorexia Nervosa, Atypical, Anorexia Nervosa
Frequency of Hypermobility-Related Problems in Patients With Anorexia Nervosa
The purpose of this study is to examine the frequense of generalized hypermobility and pain in patients with Anorexia Nervosa. The study further explores two main questions: (1) whether generalized hypermobility may be an…
- Trial name
- NCT07159867
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Vastra Gotaland Region
Instability, Joint
Comparative Effects of Closed Kinetic Chain Exercises and Thrower's Ten Exercises in Glenohumeral Instability
The study is randomized and single-blinded. Ethical approval is taken from ethical committee of Riphah International University, Lahore.
- Trial name
- NCT07724977
- Testing
- closed kinetic chain exercises, thrower's ten exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Anterior Shoulder Dislocation, Joint Instability
Anterior Shoulder Instability Treated With a Semitendinosus Subscapular Sling Procedure
The arthroscopic subscapular sling procedure is a new technique for shoulder stabilization, which has been developed in human cadaveric studies by Klungsøyr et al, but has yet to be tested clinically.
- Trial name
- NCT03424421
- Testing
- subscapular sling
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Helse Møre og Romsdal HF
Instability, Joint
Effect of Core Stability Training With Foot Exercises in Chronic Ankle Instability Patients
This study aims to investigate the effects of various treatments on lumbar and ankle proprioception, balance, and foot function in patients with chronic ankle instability.
- Trial name
- NCT07731035
- Testing
- conventional physical therapy, Core stability training, intrinsic foot muscle exercises
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Shoulder Anterior Latarjet Instability
Does Capsuloplasty Reduce External Rotation After Coracoid Impingement?
The coracoid anchor (Latarjet procedure) is the gold standard technique for treating recurrent anterior shoulder instability. Despite excellent postoperative stability, a reduction in external rotation has been reported, which…
- Trial name
- NCT07520669
- Testing
- Open coracoid impingement repair without capsuloplasty, Open coracoid impingement repair with capsuloplasty
- Where
- France
- Volunteers
- 104 people
- Sponsor
- Clinique du Sport, Bordeaux Mérignac
Elbow Joint Destruction, Post-traumatic Lesions
Clinical Outcomes Study of the Nexel Total Elbow
The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
- Conditions
- Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis
- Trial name
- NCT02469662
- Testing
- Nexel Total Elbow
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 134 people
- Sponsor
- Zimmer Biomet
Wrist Joint Hypermobility
Effect of Kinesio-taping With Routine Physical Therapy in Wrist Joint Hypermobility
The study will be randomized controlled trial. This study will be conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT07639918
- Testing
- Routine Physical Therapy Protocol for Wrist Joint, Kinesio Taping (Y-strip Technique)
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- University of Lahore
Joint Hypermobility, Adolescent Idiopathic Scoliosis
Hypermobility, Foot Posture, and Scoliosis Severity
Adolescent Idiopathic Scoliosis is a three-dimensional spinal deformity that may also affect joint mobility, lower limb alignment, and overall posture.
- Conditions
- Joint Hypermobility, Adolescent Idiopathic Scoliosis, Foot Posture
- Trial name
- AIS (NCT07249541)
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Istinye University
ADHD, Benign Joint Hypermobility Syndrome
Evaluation of Benign Joint Hypermobility and Serum Prolidase Levels in Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (ADHD) Compared to Healthy Controls
This cross-sectional observational study investigates the clinical and biochemical relationship between Attention-Deficit/Hyperactivity Disorder (ADHD) and Benign Joint Hypermobility Syndrome (BJHS) in pediatric patients.
- Conditions
- ADHD, Benign Joint Hypermobility Syndrome, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
- Trial name
- NCT07663383
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint
Post-Market Clinical Follow-Up (PMCF) Study Evaluating the Safety and Efficacy of Tıpmed™ Revision Hip Prosthesis System
This is a multicenter, prospective, observational, post-market clinical follow-up (PMCF) study designed to evaluate the safety and clinical performance of the Tipmed™ Revision Hip Prosthesis System in adult participants…
- Conditions
- Revision Hip Arthroplasty, Aseptic Loosening of Prosthetic Joint, Prostheses-related Infections, Joint Instability
- Trial name
- NCT07653295
- Testing
- Tıpmed™ Revision Hip Prosthesis System
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- TIPMED Medical Device Manufacturing Ltd. Co.
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction
STABILITY 2: Anterior Cruciate Ligament Reconstruction +/- Lateral Tenodesis With Patellar vs Quad Tendon
Anterior cruciate ligament (ACL) rupture is one of the most common musculoskeletal injuries in young individuals, particularly those that are active in sports.
- Conditions
- Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Reconstruction, Joint Instability
- Trial name
- STABILITY 2 (NCT03935750)
- Testing
- Anterior cruciate ligament reconstruction (ACLR), Lateral extra-articular tenodesis (LET)
- Where
- 31 sites in United States, Canada and 6 more
- Volunteers
- 1,272 people
- Sponsor
- University of Pittsburgh