Clinical trials: Instrumentation
Infertility
TICON-Day 3, Time Lapse Versus Conventional Method in Day 3 Embryo Culture and Assessment
The main purpose of the study was to evaluate the overall clinical value of GERI+ as an integrated embryo culture and assessment system, providing an undisturbed culture environment, continuous monitoring of embryo development…
- Trial name
- TICON (NCT03164551)
- Testing
- GERI+ incubator, Conventional incubator
- Where
- 17 sites in Canada, Denmark and 5 more
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Arterial and Midline Catheterization
Computer Assisted Instrument Guidance (CAIG) For Arterial Line Placement
The objective of this research is to verify the procedural improvements enabled by use of a CAIG system to supplement existing ultrasound guided, needle-based procedures.
- Trial name
- NCT02584673
- Testing
- Computer Assisted Instrument Guidance (CAIG), which supplements existing ultrasound capabilities.
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Clear Guide Medical
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
Femoral Shaft Fracture
TRIGEN SURESHOT™ Distal Targeting System Study
The objective of this study is to quantitate the amount of radiation both subjects and surgeons are exposed to during intramedullary nailing of the femur using the TRIGEN SURESHOT Distal Targeting System versus Standard nailing…
- Trial name
- Sureshot (NCT01327508)
- Testing
- TRIGEN SURESHOT Distal Targeting Instrumentation., Free-hand technique
- Where
- 7 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Smith & Nephew, Inc.
Degenerative Disc Disease
TXA in Spinal Fusion
Tranexamic acid and placebo will be given during surgery to patients who have elected to undergo lumber interbody fusion on 2 or more levels.
- Trial name
- NCT04272606
- Testing
- Tranexamic Acid, Saline Solution, Visual Acuity Exam
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Catherine R. Olinger
Osteoarthritis of Knee
Total Knee Replacement Component Alignment Using Manual Versus Custom Instrumentation
1. To determine whether the low-dose, biplanar x-ray imaging (EOS) has the same accuracy as computed axial tomography (CT) 2. To validate low-dose, biplanar x-ray imaging (EOS) as a tool to evaluate 3-dimensional alignment of…
- Trial name
- NCT02579174
- Testing
- Medacta GMK Sphere
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Northwestern University
Rotator Cuff Injuries, Shoulder Pain
Anaverse™ Glenoid System and Its Instrumentation
The objectives of this study are to confirm safety, performance and clinical benefits of the Anaverse™ Glenoid System and its instrumentation by analysis of standard scoring systems, radiographs and adverse event records.
- Conditions
- Rotator Cuff Injuries, Shoulder Pain, Arthropathy, Arthroplasty Complications
- Trial name
- NCT05215600
- Testing
- Anaverse Shoulder System
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Zimmer Biomet
Intervertebral Disk Degeneration
An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation
The aim of this trial is to evaluate if P-15 bone putty (investigational device) is not inferior in effectiveness and safety to local autologous bone (control device) when applied in instrumented anterior cervical discectomy and…
- Trial name
- NCT00310440
- Testing
- P-15 Synthetic osteoconductive bone substitute, Autologous bone
- Where
- 12 sites in United States, Canada
- Volunteers
- 319 people
- Sponsor
- CeraPedics, Inc
Peripheral Nerve Blocks
Computer Assisted Instrument Guidance (CAIG) for Orthopedic Peripheral Nerve Blocks
The objective of this research is to determine if the addition of the Clear Guide ONE, a Computer Assisted Instrument Guidance (CAIG) system, provides improvement over existing ultrasound guided, needle-based procedures for…
- Trial name
- NCT02614222
- Testing
- Peripheral Nerve Blocks with CAIG
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Clear Guide Medical
Osteoarthritis, Osteoarthritis, Knee
Oxford Signature vs. Conventional Global Study
This study will compare alignment criteria in the Oxford Partial Knee using conventional instrumentation and Signature Custom Guides in order to determine if the use of the Signature Custom Guides results in a higher percentage…
- Conditions
- Osteoarthritis, Osteoarthritis, Knee, Osteonecrosis
- Trial name
- NCT01763684
- Testing
- Signature Custom Guides, Conventional Instrumentation
- Where
- 7 sites in United States
- Volunteers
- 266 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Custom Cutting Block Instrument vs Regular Instrumentation Total Knee Replacement (TKR)
To determine if the use of patient-specific custom cutting blocks for implantation of total knee components results in improved limb alignment and component positioning compared to regular instrumentation.
- Trial name
- NCT03416946
- Testing
- Visionaire, Traditional
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Innovation Centre
Acetabulum Fracture, Pelvic Ring Fracture
PMCF Study on the Safety, Performance and Clinical Benefits Data of the Zimmer® Reconstruction System
The study is a monocentric, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the Reconstruction System…
- Trial name
- NCT05215626
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee
Persona TKA With iASSIST Knee System and iASSIST Knee System
The purpose of this study is to compare the accuracy of knee component alignment between patients operated with iASSIST Knee (Investigational group) versus patients operated without iASSIST Knee (Control group) using the same…
- Trial name
- NCT03227692
- Testing
- Persona Knee System, Total Knee Arthroplasty, iAssist Knee
- Where
- 3 sites in Japan
- Volunteers
- 93 people
- Sponsor
- Zimmer Biomet
Distal Radius Fracture, Distal Ulna Fracture
PMCF Study on the Safety, Performance and Clinical Benefits of the DVR Plating System
The study is a single-center, retrospective, non-randomized, non-controlled and consecutive series post-market study. The purpose of this study is to confirm safety, performance and clinical benefits of the DVR Plates.
- Conditions
- Distal Radius Fracture, Distal Ulna Fracture, Osteotomy
- Trial name
- NCT04653051
- Where
- United Kingdom
- Volunteers
- 111 people
- Sponsor
- Zimmer Biomet
Wrist Arthropathy
Wrist Arthroscopy Study
The purpose of this study is to evaluate the diagnostic efficacy of Arthrex NanoScope compared to conventional arthroscopic instruments.
- Trial name
- NCT04457362
- Testing
- Diagnostic Arthroscopy using the Arthrex NanoScope, Diagnostic Arthroscopy using standard arthroscopic instruments
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Pulmonary Arterial Hypertension
Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT Instrument
SYMPHONY Extension is an extension of AC-055-401, a multi-center, open-label, single-arm, Phase 3b study of macitentan in patients with Pulmonary Arterial Hypertension to psychometrically validate the PAH-SYMPACT instrument.
- Trial name
- SYMPHONYext (NCT01847014)
- Testing
- Macitentan
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Actelion
Avascular Necrosis, Post-traumatic; Arthrosis
iAssist vs. Conventional Instrumentation in Total Knee Arthroplasty
The purpose of this prospective study is to evaluate Zimmer® iASSIST™ with respect to radiographic, clinical and economic outcomes and compared to conventional instrumentation in primary total knee arthroplasty (NexGen or Persona…
- Conditions
- Avascular Necrosis, Post-traumatic; Arthrosis, Knee Osteoarthritis
- Trial name
- NCT03111407
- Testing
- total knee arthroplasty
- Where
- 3 sites in Spain, Switzerland
- Volunteers
- 72 people
- Sponsor
- Zimmer, GmbH
Dysphagia, Oral Pharyngeal Cancer
Pilot Study to Improve Therapeutic Outcomes for Dysphagia After Radiation Therapy
Patients with head and neck cancer treated with chemoradiation, often develop a treatment associated dysphagia. The common complaint is foods sticking in the pharynx.
- Trial name
- NCT02564887
- Testing
- Iowa Oral Performance Instrument
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Jonas Johnson
Anatomic Total Shoulder Arthroplasty
Use of Real Time Instrumentation (RTI) in Total Shoulder Arthroplasty
Glenoid component loosening is the most common complication of total shoulder arthroplasty. Loosening is associated with malposition of the implant as well as the quality of the glenoid bone.
- Trial name
- RTI (NCT01905241)
- Testing
- Anatomic TSA using RTI, Anatomic Total Shoulder Arthroplasty
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The Cleveland Clinic
Brain Injuries, Traumatic
INTRuST Structured Assessment For Evaluation of TBI (SAFE-TBI)
The current study will evaluate the initial reliability and validity of a new instrument, the INTRuST Structured Assessment for Evaluation of TBI (SAFE-TBI), in three samples of Operation Enduring Freedom/Operation Iraqi…
- Trial name
- SAFE-TBI (NCT01554891)
- Where
- 6 sites in United States
- Volunteers
- 305 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium