Clinical trials: Insufflation
Ventilation Therapy; Complications, Airway Clearance Impairment
In-line Mechanical Insufflation-Exsufflation in the Management of Ventilated Patients
Catheter suction (CS), the standard method for airway secretion management during mechanical ventilation, is invasive and has significant hemodynamic and traumatic side effects.
- Trial name
- NCT05365620
- Testing
- Mechanical In-Line Inexsufflation, catheter suction
- Volunteers
- 120 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Esophageal Motility Disorders
U-POEM vs CO2-POEM
Multicenter randomized trial comparing post-procedural pain intensity after Per-Oral endoscopic myotomy (POEM) between two types of standard of care insufflation methods (CO2 vs Underwater).
- Trial name
- U-POEM (NCT06918730)
- Testing
- U-POEM, CO2-POEM
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- AdventHealth
Colon Disease, Rectal Disease
Water Injection Colonoscopy vs Air Insufflation Colonoscopy in Training the Beginners
Water injection colonoscopy has been a generally accepted method in training the beginners of colonoscopy for its low pain and less cecal intubation time, we would conduct this study to investigate more advantages of this method…
- Conditions
- Colon Disease, Rectal Disease, Pain
- Trial name
- NCT01762735
- Testing
- Air insufflation, Water injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Youlin Yang ,MD
MRI
MRI Study of the Gastric Insufflation After High-flow Nasal Oxygen (HFNO)
HFNO CAN BE USED AS A PREOXYGENATION TECHNIQUE BUT IS IT A SAFE TECHNIQUE IN TERMS OF GASTRIC INSUFFLATION?
- Trial name
- NCT04735276
- Testing
- HFNO for 5 min
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Colonoscopy, Children
Insufflation in Children Undergoing Colonoscopy
Studies in adults have shown that post-procedural abdominal pain is reduced with the use of CO2 instead of air for insufflation during colonoscopy.
- Trial name
- NCT02407639
- Testing
- CO2, air
- Where
- Slovenia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Respiratory Failure, Hypoxia
HVNI vs NIPPV in Type 2 Respiratory Failure
The purpose of this study is to determine if high velocity nasal insufflation (HVNI) is comparable to non-invasive positive pressure ventilation (NIPPV) in treatment of emergency patients with acute respiratory acidosis.
- Conditions
- Respiratory Failure, Hypoxia, Hypercapnia
- Trial name
- SHINE (NCT07065656)
- Testing
- Vapotherm high velocity therapy (HVT) 2.0 (Vapotherm, Inc, Exeter, NH), Respironics Vision V60
- Volunteers
- 84 people
- Sponsor
- National University Hospital, Singapore
Endotracheal Tube, Tracheostomy
Safety of Mechanical Insufflation-exsufflation and Hypertonic Saline
Conventional catheter suctioning of respiratory tract secretions is a mandatory procedure in intubated patients. Poor tolerance, pain and other, sometimes severe, lung and cardiovascular complications may occur during suctioning.
- Trial name
- SMASH (NCT03940118)
- Testing
- Catheter secretion suctioning, Secretion suctioning + hypertonic saline, Ins-exsufflation
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Hospital San Carlos, Madrid
Gastric Insufflation
Gastric Insufflation and Laryngeal Mask Airway
Comparison of the incidence of gastric insufflation between two kinds of laryngeal masks airways: LMA SupremeTM vs Ambu AuraOnceTM
- Trial name
- NCT02097771
- Testing
- LMA SupremeTM, AuraOnceTM
- Where
- France
- Sponsor
- Lionel Bouvet
Laryngeal Masks Comparison, Elective Surgeries
Comparing the Effect of LTS and Air-Q sp3G LMA Use on Gastric Insufflation Using Ultrasound
The primary objective of the study is to evaluate gastric insufflation during the use of two different airway devices (Laringeal Tube Suction and Air Q sp3G Laryngeal Mask.
- Conditions
- Laryngeal Masks Comparison, Elective Surgeries, Gastric Ultrasonography, Gastric Insufflation
- Trial name
- NCT07196137
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people
- Sponsor
- Ankara City Hospital Bilkent
Right Colon Adenoma Detectation Rate, Water Exchange Colonoscopy
Right Colon Adenoma Detection Rate Using Water Exchange Versus Air Insufflation in Colonoscopy.
Although colonoscopy is currently regarded as the gold standard to detect and prevent colorectal cancer (CRC) but post-colonoscopy CRCs (interval cancer, IC) still occur.
- Trial name
- NCT07456007
- Testing
- Right colon water exchange, Air nsufflation
- Where
- Taiwan
- Volunteers
- 414 people
- Sponsor
- Dalin Tzu Chi General Hospital
Neuromuscular Diseases, Children, Only
Mechanical Cough Augmentation in Children With NMD
The study investigates the prevalence and use of mechanical insufflation - exsufflation (MI-E) in children with Neuromuscular disorders (NMD) in Norway.
- Conditions
- Neuromuscular Diseases, Children, Only, Airway Clearance Impairment, Cough
- Trial name
- NCT03831568
- Where
- Norway
- Volunteers
- 72 people
- Sponsor
- Oslo University Hospital
Lumbar Spinal Stenosis
The Utility of Oxygen Insufflation During Flexible Fiberoptic Bronchoscope-guided Intubation
This study investigate the utility of continuous oxygen insufflation during fiberoptic bronchoscope-guided intubation. One group receives oxygen via suction channel of fiberoptic bronchoscope during intubation.
- Trial name
- NCT02625194
- Testing
- Oxygen
- Where
- South Korea
- Volunteers
- 36 people
- Sponsor
- Yonsei University
Pneumoperitoneum
A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy
The investigators hypothesize that using carbon dioxide for PEG placement versus using room air will decrease post-procedure pneumoperitoneum as well as improve post-procedure bloating/pain, and waist circumference.
- Trial name
- NCT02619656
- Testing
- CO2 insufflation, Ambient air insufflation
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Shoulder Pain
Pneumoperitoneum Management With SurgiQuest AirSeal at Low vs. Higher Pressure ( PRESSURE )
This study is designed to evaluate physician preference related to the use of the SURGIQUEST AIRSEAL® INSUFFLATION SYSTEM (AIS) at low verses high pressure for the management of pneumoperitoneum.
- Trial name
- PRESSURE (NCT02541448)
- Testing
- SurgiQuest AIRSEAL® Insufflation System (AIS)
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Cynthia Harris
Surgery, Pneumoperitoneum
Intra-Abdominal Pressure Effect on Intra-Abdominal Volume and Airway Pressures During Laparoscopy
During pneumoperitoneum insufflation the insufflated gas increase intra-abdominal pressure. The generated pressure can lead to a different increase in volume depending on the abdominal cavity and patients' characteristics.
- Conditions
- Surgery, Pneumoperitoneum, Intra Abdominal Pressure
- Trial name
- NCT04468698
- Testing
- Peritoneum insufflation
- Where
- Spain
- Volunteers
- 204 people
- Sponsor
- Hospital Universitario La Fe
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Cholecystolithiasis
Warmed, Humidified Carbon Dioxide Insufflation vs Standard Carbon Dioxide in Laparoscopic Cholecystectomy
The purpose of this study is to determine the effect of warmed, humidified carbon dioxide Insufflation vs standard carbon dioxide in laparoscopic cholecystectomy.
- Trial name
- NCT01667848
- Testing
- Optitherm® device activated, Optitherm® device inactivated
- Where
- Austria
- Volunteers
- 148 people
- Sponsor
- Kepler University Hospital
Airway Management, Induction of Anesthesia
The 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction
Exploring the 90% Effective Ventilation Pressure (EP90) for Esophageal Insufflation Avoidance During Anesthesia Induction: The aim is to determine the optimal ventilation pressure for esophageal insufflation avoidance during…
- Trial name
- NCT07340255
- Testing
- Ultrasonic and inflation determination
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Affiliated Hospital of Jiaxing University
Insertion of a Flexible Bronchoscope, Airway Management When Secretions Obstruct the Larynx
Oxygen Insufflation Via Flexible Scope
The investigators will study to what extent insufflation of oxygen via the suction channel of a flexible bronchoscope can help with making access from the mouth to the trachea easier when there is blood or secretions in the way.
- Trial name
- OxyInsuffl (NCT06680648)
- Testing
- addition of oxygeninsufflation via working channel of flexible scope, no-oxygen insufflation
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet