Clinical trials: Insufflation
MRI
MRI Study of the Gastric Insufflation After High-flow Nasal Oxygen (HFNO)
HFNO CAN BE USED AS A PREOXYGENATION TECHNIQUE BUT IS IT A SAFE TECHNIQUE IN TERMS OF GASTRIC INSUFFLATION?
- Trial name
- NCT04735276
- Testing
- HFNO for 5 min
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Liege
Colonoscopy, Children
Insufflation in Children Undergoing Colonoscopy
Studies in adults have shown that post-procedural abdominal pain is reduced with the use of CO2 instead of air for insufflation during colonoscopy.
- Trial name
- NCT02407639
- Testing
- CO2, air
- Where
- Slovenia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Insertion of a Flexible Bronchoscope, Airway Management When Secretions Obstruct the Larynx
Oxygen Insufflation Via Flexible Scope
The investigators will study to what extent insufflation of oxygen via the suction channel of a flexible bronchoscope can help with making access from the mouth to the trachea easier when there is blood or secretions in the way.
- Trial name
- OxyInsuffl (NCT06680648)
- Testing
- addition of oxygeninsufflation via working channel of flexible scope, no-oxygen insufflation
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Surgery, Anesthesia
Comparison of Gastric Insufflation With the Classic Igel Laryngeal Mask and the New Igelplus Laryngeal Mask Using Gastric Ultrasound
This study aims to compare the effectiveness and safety of two types of laryngeal masks- iGel and iGel Plus, used during elective surgeries.
- Trial name
- NCT06578598
- Testing
- Igelplus
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Luzerner Kantonsspital
Gynecologic Diseases
AirSeal®Insufflation Trocar/CO2 Absorption Study
The purpose of this study is to compare carbon dioxide (CO2) absorption during gynecologic laparoscopy using the AirSeal® valveless trocar system versus standard insufflation trocars at intra-abdominal pressures of 10 and 15…
- Trial name
- NCT02654808
- Testing
- AirSeal trocar, Standard trocar
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Columbia University
Colonoscopy Education
Comparing Clinical Performance of Novice Trainee Endoscopists Using Conventional Air Insufflation Versus Warm Water Infusion Colonoscopy
Hypothesis: Novice trainees will achieve significantly higher clinical competence and patient satisfaction scores with the use of warm water infusion method when compared with traditional air insufflation Primary outcome: adenoma…
- Trial name
- NCT01482546
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Apnea, Ventilation Therapy; Complications
THRIVE in Children at Different Flow Rates
This study investigates under controlled circumstances the concept of THRIVE to improve the ventilation and the carbon dioxide elimination, to prolong the apnoea time without deoxygenation and to improve safety of airway…
- Trial name
- NCT03812354
- Testing
- THRIVE 4L/kg/min, THRIVE 2L/kg/min
- Where
- 2 sites in Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Oxygen Deficiency, Desaturation of Blood
THRIVE Use in Pediatric Populations- Multi Site
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT04322994
- Testing
- Transnasal Humidified Rapid-Insufflation Ventilatory Echange
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Stanford University
Water Assisted Colonoscopy
Impact of Water Assisted Colonoscopy vs Air Insufflation on Resident Training
This study will be a randomized trial comparing the use of only water or water and air insufflation during colonoscopy insertion by trainees.
- Trial name
- NCT04987645
- Testing
- Water-only infusion technique, Water infusion and air insufflation
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Colonoscopy
Comparisons of SWI, WWI and CI in Potentially Difficult Colonoscopy.
Colonoscopy insertion is technically challenging, time-consuming, and painful, especially for the sigmoid. It is reported that the difficult colonoscopy score (DCS) >1 can predict the difficulty during colonoscopy.
- Trial name
- NCT03571061
- Testing
- whole colon water immersion and sigmoid water immersion
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Air Insufflation, Regurgitation
Risk of Gastric Insufflation Related to Facemask Ventilation Technique During Anaesthetic Induction, With or Without PEEP
Continuous positive pressure during anesthetic induction is today not routinely used partly a to the risk of gastric insufflation because of higher ventilatory pressures.
- Trial name
- NCT02238691
- Testing
- Mask ventilation with PEEP via a face mask device
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Örebro University, Sweden
Children
The Laryngeal Mask Airway (LMA) Unique and the Air-Q Intubating Laryngeal Airway (ILA) in Pediatric Patients
The air-Q® intubating laryngeal airway (ILA) is an supraglottic device used for both airway maintenance during routine anesthesia and as a conduit for tracheal intubation for patients with a difficult airway.
- Trial name
- NCT01314248
- Testing
- each child will receive both the LMA and ILA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Child, Anesthesia
Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in Children
The purpose of this study is to find an optimal inspiratory pressure to provide adequate tidal volume and prevent gastric insufflation in pediatric patients.
- Trial name
- NCT02471521
- Testing
- Mask ventilation, Rocuronium
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Gastric Insufflation
Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
The purpose of this study is to determine whether mechanical ventilation with facial mask during induction anesthesia in the population of 1month to 14years is associated with less risk of gastric insufflations as compared with…
- Trial name
- NCT01652924
- Testing
- Mechanical ventilation with facial mask, Manual ventilation with facial mask
- Where
- Colombia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Colorectal Cancer, Colorectal Adenomas
Water Exchange Versus Carbon Dioxide for Colonoscopy
Colonoscopy is commonly used in screening for colorectal cancer. A refined technique of colonoscopy involving the use of water as the sole modality to aid colonoscope insertion, water exchange, has been described in recent…
- Conditions
- Colorectal Cancer, Colorectal Adenomas, Colorectal Polyps, Pain
- Trial name
- NCT01633333
- Testing
- Water exchange colonoscopy, Carbon dioxide insufflation
- Where
- 3 sites in Norway, Poland
- Volunteers
- 473 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy
Compared with the conventional (air) method, patients examined by the study (water) method have lower pain scores and require less medication but have similar cecal intubation rate and willingness to repeat future colonoscopy.
- Trial name
- NCT00785889
- Testing
- water infusion colonoscopy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Colorectal Cancer Screening
Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance
Hypothesis 1. Study method achieves lower requirement for medications 2. Study method increases overall cecal intubation with comparable assessment of current experience and patient willingness to repeat future colonoscopy…
- Trial name
- NCT00920751
- Testing
- Water infusion, Air insufflation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Apnea, Ventilation Therapy; Complications
THRIVE Apneic Ventilation With Standardized Airway Management During General Anesthesia.
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) denotes the use of high-flow humidified nasal oxygen system (for example Optiflow®) as an alternative ventilation modality for an anesthetized patient without…
- Conditions
- Apnea, Ventilation Therapy; Complications, Respiratory Acidosis
- Trial name
- NCT03797859
- Testing
- Apneic ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet