Clinical trials: Insufflation
Children
The Laryngeal Mask Airway (LMA) Unique and the Air-Q Intubating Laryngeal Airway (ILA) in Pediatric Patients
The air-Q® intubating laryngeal airway (ILA) is an supraglottic device used for both airway maintenance during routine anesthesia and as a conduit for tracheal intubation for patients with a difficult airway.
- Trial name
- NCT01314248
- Testing
- each child will receive both the LMA and ILA
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Colonoscopy, Gastrointestinal Microbiome
Effect of Carbon Dioxide Insufflation and Appendix on the Restoration of Intestinal Microecology After Colonoscopy.
The goal of this observational study is to learn about Influencing factors of intestinal microecological changes before and after colonoscopy.
- Conditions
- Colonoscopy, Gastrointestinal Microbiome, Appendix, Carbon Dioxide Insufflation
- Trial name
- NCT05637021
- Testing
- Carbon dioxide insufflated during colonoscopy
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Zhongshan Hospital Xiamen University
Colorectal Cancer
RCT of Air Insufflation Versus Water Infusion Colonoscopy
Compared with the conventional (air) method, patients examined by the study (water) method have lower pain scores and require less medication but have similar cecal intubation rate and willingness to repeat future colonoscopy.
- Trial name
- NCT00785889
- Testing
- water infusion colonoscopy
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Carbon Dioxide Insufflation
The Application of CO2 Insufflations in Routine Colonoscopy Examination for Duration in Toilet After Examination Compared With Air Insufflations
It has been reported that carbon dioxide (CO2) insufflation can reduce patient pain and abdominal discomfort during and after colonoscopy.
- Trial name
- NCT01807312
- Testing
- Endoscopic CO2 regulation unit and accessories
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Neoplasm, Colorectal Cancer
Application of CO2 Insufflations in Colonoscopy Randomized Trial
It has been reported that carbon dioxide (CO2) insufflation can reduce patient pain and abdominal discomfort during and after colonoscopy.
- Trial name
- NCT00745927
- Testing
- CO2 insufflations
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Child, Anesthesia
Optimal Inspiratory Pressure for Facemask Pressure-controlled Ventilation in Children
The purpose of this study is to find an optimal inspiratory pressure to provide adequate tidal volume and prevent gastric insufflation in pediatric patients.
- Trial name
- NCT02471521
- Testing
- Mask ventilation, Rocuronium
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Gastric Insufflation
Efficacy of Mechanical Ventilation With Facial Mask to Reduce Gastric Insufflation
The purpose of this study is to determine whether mechanical ventilation with facial mask during induction anesthesia in the population of 1month to 14years is associated with less risk of gastric insufflations as compared with…
- Trial name
- NCT01652924
- Testing
- Mechanical ventilation with facial mask, Manual ventilation with facial mask
- Where
- Colombia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Pain, Pneumoperitoneum
Comparison of Pneumoinsufflation Modes and Pressure Settings in Gynecology
This study seeks to evaluate post-operative patient pain and quality of life, and intra-operative hemodynamic status and changes in inflammatory markers, with use of a pressure-barrier insufflator and conventional insufflator at…
- Conditions
- Pain, Pneumoperitoneum, Inflammation, Quality of Life
- Trial name
- NCT02853591
- Testing
- Pneumoinsufflator mode and setting
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Bladder Integrity, Bladder Function
Trendelenburg, Abdominal Insufflation and Time to Completion of Cystoscopy
Objective: The investigators seek to compare the efficiency of the cystoscopy with two interventions: 1. patient position during the cystoscopy (Trendelenburg (head down) or flat) 2.
- Conditions
- Bladder Integrity, Bladder Function, Ureteral Integrity, Ureteral Function
- Trial name
- NCT05786391
- Testing
- Flat position, Trendelenburg position, Insufflation
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Gastric Insufflation
Comparison of Gastric Insufflation Volume Between LarySeal Pro and Ambu AuraGain Using Ultrasonography In Pediatric Patients Undergoing General Anesthesia With Controlled Ventilation.
Gastric air insufflation during insertion of a laryngeal mask airway (LMA) is a known phenomenon and can have important clinical implications, especially in relation to: During positive pressure ventilation or improper insertion…
- Trial name
- NCT07451470
- Testing
- LarySeal Pro, Ambu aura
- Where
- Egypt
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Section Complications, Pregnancy Related
Assessment of Transnasal Humidified Rapid-insufflation Ventilatory Exchange (THRIVE) for Maternal Pre-oxygenation
The main objective of this study is to determine if the use of transnasal humidified rapid-insufflation ventilatory exchange (THRIVE) can reduce by 90 seconds the time between the entry into the operating room of the volunteer…
- Conditions
- Cesarean Section Complications, Pregnancy Related, Anesthesia
- Trial name
- PREOXCE (NCT04814628)
- Testing
- scenario 1 : pre-oxygenation with a face mask held by the anaesthetist, scenario 2: one anaesthetist in charge, face mask held by the patient for pre-oxygenation, scenario 3: one anaesthetist in charge, THRIVE used for pre-oxygenation
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Carbon Dioxide Insufflation, Anterograde Single Balloon Enteroscopy
Comparison Air Versus Carbon Dioxide Insufflation in Single Balloon Anterograde Enteroscopy
Observation study comparing patient symptoms of bloating, pain, and nausea between CO2 insufflation vs. O2 insufflation in anterograde balloon enteroscopy.
- Trial name
- NCT03811522
- Testing
- carbon dioxide insufflation, Air insufflation
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- North Eastern Ohio Gastroenterology and Endoscopy center
Laparoscopic Surgery
Blunt Fascial vs. Veress Needle Peritoneal Entry in Laparoscopic Gynecologic Surgery
This study aims to investigate the effect of two peritoneal entry techniques on intraoperative and post-operative outcomes among patients undergoing laparoscopic surgery with a minimally invasive gynecologic surgeon.
- Trial name
- BluntFascial (NCT06305975)
- Testing
- Blunt fascial abdominal entry, Veress needle abdominal entry
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Obesity, Anesthesia
Pre-oxygenation Methods in Bariatric Patients
The purpose of the study is to compare effectiveness of different methods of achieving pre-oxygenation in bariatric patients. The investigators intend to compare facemask pre-oxygenation with a high-flow humidified nasal oxygen.
- Conditions
- Obesity, Anesthesia, Bariatric Surgery Candidate
- Trial name
- NCT03428256
- Testing
- Optiflow and THRIVE technique, Standard anaesthetic face mask
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Screening Colonoscopy
Comparison of Adenoma Detection Rate Among Water, Carbon Dioxide and Air Methods of Minimal Sedation Colonoscopy
The purpose of this study is to determine which of the methods of colonoscopy viz. water insufflation or air insufflation or carbon dioxide insufflation is better in detecting the adenomas in colon and also which of these methods…
- Trial name
- NCT01782014
- Testing
- colonoscopy
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Outpatients
The Optimal Timing of Carbon Dioxide Insufflation During Colonoscopy in Unsedated Patients
Insufflation of carbon dioxide (CO2) instead of air can reduce pain resulting from colon distension after colonoscopy because CO2 is rapidly absorbed from the colon and excreted through the lungs.
- Trial name
- NCT01415076
- Testing
- Insufflation with CO2
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
COPD
Pathogenesis and Outcomes of Sleep Disordered Breathing in Chronic Obstructive Pulmonary Disease (COPD)
This research is being conducted to examine the effects of nasal insufflation of warm and humidified air through a small nasal cannula on sleep, breathing pulmonary function, and daytime exercise capability.
- Trial name
- NCT01764165
- Testing
- Oxygen, High flow of room air
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Colorectal Cancer Screening
Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance
Hypothesis 1. Study method achieves lower requirement for medications 2. Study method increases overall cecal intubation with comparable assessment of current experience and patient willingness to repeat future colonoscopy…
- Trial name
- NCT00920751
- Testing
- Water infusion, Air insufflation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Colonoscopy, Children
Insufflation in Children Undergoing Colonoscopy
Studies in adults have shown that post-procedural abdominal pain is reduced with the use of CO2 instead of air for insufflation during colonoscopy.
- Trial name
- NCT02407639
- Testing
- CO2, air
- Where
- Slovenia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana