Clinical trials: Insulin Pump Therapy
Diabetes Type 1
Transition of T1DM Patients Aged Over 65 Years Into AHCL (780G) Insulin Pump
Older people with diabetes have a higher risk for cognitive impairment and for physical disability whether this may be effected by an improvement in glucose indices is unknown.
- Trial name
- 780G65+ (NCT06207838)
- Testing
- MiniMed 780G system
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- Jagiellonian University
Diabetes Technology, Continuous Glucose Monitoring System
Healthcare Practitioners Knowledge on Diabetes Technology
Assessment of knowledge of healthcare professionals of diabetes mellitus technology (continuous glucose monitoring systems and insulin pump therapy).
- Conditions
- Diabetes Technology, Continuous Glucose Monitoring System, Continuous Insulin Infusion System, Insulin Pump Therapy
- Trial name
- NCT07822945
- Testing
- Questionnaire assessing knowledge on diabetes technology
- Where
- Greece
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes Mellitus
Insulin-based Strategies to Prevent Hypoglycemia During Exercise
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise.
- Trial name
- NCT03349489
- Testing
- Exercise 1, Exercise 2, Dexcom G4 Platinum
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Diabetes Mellitus
Inflammatory Response to CSII Catheters in a Tummy Tuck Model
In insulin pump therapy, insulin is continuously infused into the subcutaneous adipose tissue via a continuous subcutaneous insulin infusion (CSII) catheter using a basal/bolus pattern.
- Trial name
- IRCATT (NCT03298295)
- Testing
- Continous Subcutaneous Insulin Infusion Catheter
- Where
- Austria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Type 1 Diabetes
Clinical Efficacy of Insulin Pumps in Type 1 Diabetes Mellitus Patients in Spain
Observational cross-sectional multicenter study about clinical efficacy of insulin pumps in type 1 diabetes mellitus patients.
- Trial name
- NCT04761094
- Testing
- Insulin pump
- Where
- 25 sites in Spain
- Volunteers
- 2,977 people
- Sponsor
- Castilla-La Mancha Health Service
T1DM
Glycemic Control and Treatment Satisfaction in Children With Type 1 Diabetes Using Insulin Pumps
Background: The use of insulin pumps in pediatric patients with type 1 diabetes(T1D) has expanded, with lack of data comparing between the different devices.
- Trial name
- NCT03697369
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Type 1 Diabetes
SGLT2 Inhibitor Adjunctive Therapy to Closed Loop Control in Type 1 Diabetes Mellitus
The primary purpose of this study is to evaluate the safety and efficacy of combining SGLT2 inhibitors with closed loop control (CLC).
- Trial name
- CiQ-SGLT2 (NCT04201496)
- Testing
- Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks, Empagliflozin + Basal-IQ x 2 wks then Control-IQ x 4 wks, No Empagliflozin + Control-IQ x 4 wks then Basal-IQ x 2 wks
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Ananda Basu, MD
Type 1 Diabetes
Study to Assess the Metabolic Impact of IRTA© and Patients Satisfaction in Type 1 Diabetic Patients, Treated by Either Insulin Pump or Multiple Daily Insulin Injections, and Using Freestyle Libre®, a Real-time Continuous Glucose Monitoring
A prospective monocentric " before and after " study, ruled in 2 periods of 3 months : during the first period, the patient will adjust insulin treatment as usual, during the second period, the patient will adjust insulin…
- Trial name
- IRTA (NCT04211220)
- Testing
- A decision support software
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Rennes University Hospital
Type 1 Diabetes Mellitus
VV-14299 and VV-14300 for the Treatment of Type 1 Diabetes
This study is testing VV-14299 and VV-14300 or VV-14300 alone in adults with long-standing type 1 diabetes (T1D) whose blood sugar is not well controlled despite using an automated insulin delivery (AID) system.
- Trial name
- PROGRESS (NCT07829302)
- Testing
- VV-14300, VV-14299
- Where
- Australia
- Volunteers
- 29 people
- Sponsor
- Kriya Therapeutics, Inc.
Diabetes Mellitus, Type 1, Diabetes Mellitus, Insulin-Dependent
Telemetric Glucose Data Acquisition During Initiation of Insulin Pump Therapy
This study will help determine whether the use of a wireless glucose meter and and an internet-based automated diabetes management system to organize blood glucose values will help improve glucose control during the start of…
- Trial name
- NCT00297635
- Testing
- GlucoDYNAMIX™ intervention system, GlucoMON™ telemetry device
- Sponsor
- Thomas Jefferson University
Type 1 Diabetes
New Strategies for Postprandial Glycemic Control Using Insulin Pump Therapy
Achieving near-normoglycemia has been established as the main objective for most patients with type 1 diabetes (T1DM). However, insulin dosing is an empirical process and its success is highly dependent on the patients' and…
- Trial name
- NCT01550809
- Testing
- iBolus, tBolus (traditional bolus)
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Type 1 Diabetes
Insulin-based Strategies to Prevent Hypoglycemia During Exercise
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise.
- Trial name
- NCT02631265
- Testing
- Exercise 1, Exercise 2, Exercise 3
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Psychological Aspects and Insulin Pump Therapy
The Continuous Subcutaneous Insulin Infusion (CSII) might have an impact on psychological distress and some psychological factors might be predictors of metabolic control; however, very few studies conducted so far were…
- Trial name
- NCT02138188
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- Universita di Verona
Type 1 Diabetes, Insulin Pump Therapy
Impact of Hybrid Closed Loop Systems in People With Type I Diabetes
Type 1 diabetes requires people with type 1 diabetes to constantly monitor their blood glucose and adjust their insulin doses to try and keep glucose levels in range.
- Conditions
- Type 1 Diabetes, Insulin Pump Therapy, Patient Reported Outcomes
- Trial name
- ProHCL (NCT05348499)
- Testing
- Questionnaire/Interview
- Where
- United Kingdom
- Volunteers
- 350 people
- Sponsor
- University of Leicester
Type 1 Diabetes
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 15 Weeks in Adolescents and Adults With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT02846857
- Testing
- 15-week intervention with sensor-augmented pump, 15-week intervention with single-hormone closed-loop, 15-week intervention with dual-hormone closed-loop
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Accu-Chek Combo in Young Patients
This is an open, prospective, descriptive study aiming to evaluate the change in treatment satisfaction of primary care givers of young children who use the Accu-Chek Combo System.
- Trial name
- NCT01657630
- Testing
- Accu-Chek Combo System
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Rabin Medical Center
Diabetic Gastroparesis
Continuous Glucose Monitoring and Insulin Pump Therapy in Diabetic Gastroparesis
A pilot study to assess the safety, feasibility, and potential (uncontrolled) efficacy of continuous glucose monitoring (CGMS) in conjunction with an insulin pump to improve glycemic control for treatment of type 1 and type 2…
- Trial name
- GLUMIT-DG (NCT01030341)
- Testing
- CGMS and insulin pump
- Where
- 7 sites in United States
- Volunteers
- 45 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Type 1 Diabetes
Closing the Loop for 36 Hours in Adolescents With Type 1 Diabetes
High variability of blood sugar levels and high incidence of night-time hypoglycaemia (low blood sugar) in young people with type 1 diabetes (T1D) make achieving the treatment goals in this population extremely challenging.
- Trial name
- NCT01074801
- Testing
- Closed-loop insulin delivery, Standard insulin pump treatment
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 1
Evaluation of Novel Trend Arrow Adjustment Tool for Diabetes Patients Using Continuous Glucose Monitoring to Guide Insulin Bolus Adjustment (TAAT Study)
Continuous glucose monitoring (CGM) provides up to 288 blood glucose levels per day, updated every 5 minutes and displayed in real-time on the insulin pump, which can be used to enhance delivery of insulin through pump therapy.
- Trial name
- TAAT (NCT02064647)
- Testing
- Trend Arrow Adjustment Tool, 10/20% bolus adjustment
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Children's Hospital of Eastern Ontario
Type 1 Diabetes Mellitus, Diet Modification
Safety of Low and Very Low Carbohydrate Diets in Young Children With Type 1 Diabetes
The purpose of the study is to evaluate the safety of short-term (6 month) low or very-low carbohydrate diets in prepubertal children 2 to <12 years old with type 1 diabetes.
- Conditions
- Type 1 Diabetes Mellitus, Diet Modification, Child, Only
- Trial name
- NCT03862521
- Testing
- Low carbohydrate diet, Very low carbohydrate diet
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Nemours Children's Clinic