Clinical trials: Intense Exercise, open to volunteers
Parkinson Disease
Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis
The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease.
- Trial name
- NCT07488364
- Testing
- Observational Questionnaire and Functional Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Parkinson Disease, Movement Disorders
Moderate Versus High Volume Light-Moderate Intensity Exercise for People With Moderate Parkinson's Disease
Veterans with mid to later stage Parkinson's disease (PD) may not be able to work out as hard as they need to, to prevent brain cell loss.
- Conditions
- Parkinson Disease, Movement Disorders, Neurodegeneration
- Trial name
- HI-LITE (NCT06088355)
- Testing
- HV-PDAE: High Volume Partnered Dance Aerobic Exercise, MV-PDAE: Moderate Volume Partnered Dance Aerobic Exercise, MV-WALK: Moderate Volume Walking
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- VA Office of Research and Development
Mitral Insufficiency
Assessing the Relationship Between Symptoms and Mitral Regurgitnant. Severity
The current American College of Cardiology/American Heart Association (ACC/AHA) guidelines recommend surgery in patient with mitral regurgitation (MR) based on 1) the severity of MR and 2) the presence or absence of symptoms.
- Trial name
- NCT06738615
- Testing
- Pressure volume loop evaluation, cardiovascular magnetic resonance imaging, Cardiopulmonary exercise testing (CPET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Atlantic Health System
Diet Quality, Metabolic Health
Diet, Metabolic Health, and Exercise Responses
Regular physical activity, healthy dietary habits, and good metabolic health are associated with numerous physical and cognitive health benefits.
- Conditions
- Diet Quality, Metabolic Health, Cognitive Function, Exercise Response
- Trial name
- NCT07728240
- Testing
- Standardized Moderate-Intensity Cycling Session
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, River Falls
Stroke, Stroke Rehabilitation
Biomarkers of Reaction To HIIT Exercise
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy.
- Conditions
- Stroke, Stroke Rehabilitation, Lower Extremity Weakness, Spastic, Walking, Difficulty
- Trial name
- BReaTHE (NCT06059872)
- Testing
- High Intensity Interval Training (HIIT)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- VA Office of Research and Development
Inflammation, Obesity (Disorder)
The ISAR InflEx Trial (Inflammation and Exercise)
A sedentary lifestyle and obesity are associated with chronic low-grade inflammation and an elevated risk of cardiovascular disease (CVD).
- Trial name
- InflEx (NCT07543666)
- Testing
- moderate-intensity exercise, vigorous-intensity exercise, short bouts of maximal exercise
- Where
- Germany
- Volunteers
- 33 people
- Sponsor
- Department of Cardiology German Heart Center Munich TUM University Hospital
Aphasia, Acquired, Aphasia
Aphasia Physical EXercise Study: Randomized Trial
The goal of this clinical trial is to evaluate the effects of a high-intensity exercise program on recovery in individuals with post-stroke aphasia.
- Conditions
- Aphasia, Acquired, Aphasia, Aphasia, Fluent, Aphasia, Non-fluent
- Trial name
- APEX (NCT07281313)
- Testing
- High-intensity physical exercise, Low-intensity physical exercise
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, Berkeley
Heat Stress, Temperature Change, Body
The Impact of Wearing the Hijab on Whole-body Heat Loss During Exercise-heat Stress
The hijab (headscarf and cloak) is a Muslim dress, which covers the head, neck and chest, and conceals the female hair, leaving the face uncovered.
- Trial name
- NCT07174180
- Testing
- Exercise-heat stress with no hijab, Exercise-heat stress with a hijab
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Exercise-Induced Muscle Fatigue, Fatigue Recovery
Acute Effects of High-Intensity Laser Therapy on Pain, Muscle Stiffness, and Grip Strength in Healthy Adults
The goal of this clinical trial is to learn whether high-intensity laser therapy applied before exercise reduces the loss of handgrip strength, muscle stiffness, and pain after a tiring forearm exercise in healthy adults.
- Conditions
- Exercise-Induced Muscle Fatigue, Fatigue Recovery, Health Adult Subjects, Healthy Adult
- Trial name
- HILT (NCT07895862)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Behavior
Acute Effect of Aerobic Exercise on Cardiovascular Reactivity During a Mental Stress Test in Teachers
This study will investigate the acute effect of a single session of moderate-intensity aerobic exercise on blood pressure responses to mental stress in teachers.
- Trial name
- NCT07911865
- Testing
- Acute Exercise, Control
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Federal University of Mato Grosso
Sustained Attention, Cognitive Performance
Acute Effects of Moderate-Intensity Continuous Exercise Versus HIIT on Cognitive Performance and Psychophysiological Responses in Physically Active Adults
This study aims to compare the immediate effects of two common types of exercise-moderate-intensity continuous exercise and high-intensity interval training (HIIT)-on attention, alertness, and physiological responses in…
- Conditions
- Sustained Attention, Cognitive Performance, Cognitive Performance During Physical Activity
- Trial name
- EXCOG (NCT07400432)
- Testing
- Moderate-Intensity Continuous Exercise (MICE), High-Intensity Interval Training (HIIT)
- Where
- Saudi Arabia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Qassim University
Older Adult
High-intensity Interval Training Combined with Muscle-strength Training in Older Women
Women generally live longer than men but often experience a faster muscle mass loss due to inactivity, which can lead to weakness and disability. Despite these risks, women, particularly older women, are less active than men.
- Trial name
- NCT06825130
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Lipedema, Exercise Therapy
Investigation of the Effects of High-Intensity Interval Exercise and Moderate-Intensity Continuous Exercise on Limb Volume, Functional Capacity, and Quality of Life in Patients With Lipedema
This randomized controlled clinical study aims to investigate and compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT), when combined with intermittent pneumatic…
- Conditions
- Lipedema, Exercise Therapy, High Intensity Interval Training
- Trial name
- NCT07319611
- Testing
- Intermittent Pneumatic Compression (IPC), Home-Based Walking Program, High-Intensity Interval Training (HIIT)
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Marmara University
Healthy Volunteers
Classroom Break, Cognition, and Fitness in Elementary School Children
The goal of this randomized controlled trial is to learn about the effect of a 12-week school-based intervention combining mindfulness with high-intensity interval training (MF-HIIT), MF-only intervention, and HIIT-only…
- Trial name
- NCT06258941
- Testing
- MF-HIIT, HIIT-only, MF-only
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Purdue University
Chronic Respiratory Disease, Chronic Obstructive Pulmonary Disease
High-Intensity Interval Alternating Concentric-Eccentric Training in Chronic Respiratory Disease
This randomized controlled trial aims to evaluate the effects of high-intensity interval training incorporating alternating concentric and eccentric cycling on functional performance in adults with chronic respiratory disease…
- Trial name
- Effects of Hig (NCT07867535)
- Testing
- Alternating Concentric-Eccentric High-Intensity Interval Training, Concentric High-Intensity Interval Training, Usual Care
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Fu Jen Catholic University Hospital
Stable Coronary Artery Disease (CAD), Myocardial Infarction
Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease
This study is a randomized, parallel-group clinical trial with assessor and statistical analyst blinding, conducted at a single center.
- Trial name
- NCT07485400
- Testing
- Intervention Group, Control Group (A):
- Volunteers
- 48 people
- Sponsor
- Universidad Complutense de Madrid
Attention Deficit Disorder With Hyperactivity (ADHD)
High Intensity Training for Adults With ADHD in Specialised Mental Health Care
Attention-Deficit/Hyperactivity Disorder (ADHD) is a lifelong neurodevelopmental disorder characterised by persistent symptoms of inattention, hyperactivity, and impulsivity.
- Trial name
- HITADHD (NCT07675538)
- Testing
- High intensity training
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Solli Distriktspsykiatriske Senter
Physical Activity, Physical Activity Intensity
Effects of Polarized and Threshold Intensity Distribution Models on Race Time and Body Composition in Recreational Runners Aged 20-45 Years.
This study aims to compare the effects of two intensity distribution training (TID) models-polarized and threshold-on 5-km race time and body composition in recreational runners aged 20 to 45 years.
- Conditions
- Physical Activity, Physical Activity Intensity, Physical Activity in Adults, Running
- Trial name
- NCT07498608
- Testing
- Polarized intensity distribution model, Threshold intensity distribution model
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad Pedagogica Nacional, Colombia
Metabolic Syndrome, Obesity and Obesity-related Medical Conditions
Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome
The goal of this intervention trial is to assess the effects of intermittent fasting, both alone and in combination with high-intensity interval training, on patients with obesity and metabolic syndrome.
- Trial name
- FIT (NCT06885255)
- Testing
- Alternate day fasting, Time restricted eating, High-intensity interval training
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Parkinson Disease
Cognitive Effects of Exercise in Parkinson's Disease
This pilot study will evaluate the short-term (3 months) and long-term (6 months) effectiveness of a high-intensity interval training (HIIT) program in improving cognitive function and self-efficacy in individuals with PD.
- Trial name
- NCT06823921
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sule Tinaz