Clinical trials: Intensive Care Medicine
Stress, Psychological, Emergency Medicine, Transport
Benefit of the FLYing Transport of Patients Requiring Mobile Intensive Care Unit
Patient care who requires fast and intensive care by a mobile intensive care unit in a rescue helicopter is a common practice in Auvergne since more than 3 years.
- Conditions
- Stress, Psychological, Emergency Medicine, Transport, Critical Care
- Trial name
- FLY-MICU (NCT04578054)
- Testing
- Flying transport
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Bacteremia, Infant, Very Low Birth Weight
Preventing Catheter-related Bacteremia When Administering Injectable Medications in Premature Infants.
This study evaluates the potential interest of a new multi-lumen infusion access device (Edelvaiss® Multiline NEO) in the prevention of catheter-related bacteremia when administering injectable drugs in premature infants.
- Trial name
- MultilineNEO (NCT02633124)
- Testing
- Edelvaiss Multiline NEO, Standard Infusion Set
- Where
- 4 sites in France
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Emergency
Variation IGFBP7 Markers and TIMP2 Induced by Injection of Contrast Iodized Drug at the Intensive Care Patient
Multicenter, prospective, uncontrolled study to evaluate variations in urinary concentrations of TIMP-2 and PCI IGFBP7 induced injection during a CT scan in intensive care patient.
- Trial name
- ContraCHECK (NCT02881710)
- Testing
- contrast product used to assess biomarkers variations
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Extreme Prematurity, Neurodevelopmental Abnormality
Osteopathic Manipulative Medicine to Reduce Developmental Delays
This randomized clinical trial seeks to determine if osteopathic manipulative medicine (OMM) increases the likelihood of improved neurodevelopmental outcomes as estimated by the Test of Infant Motor Performance (TIMP).
- Trial name
- NCT04652063
- Testing
- Osteopathic Manipulative Medicine
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Anxiety, Health Education
QR Code Video Education for ICU Family Members
This prospective randomized controlled study aims to evaluate the effect of a QR code-based digital information video on knowledge level and anxiety among family members of intensive care unit (ICU) patients.
- Conditions
- Anxiety, Health Education, Family Members of Intensive Care Unit Patients
- Trial name
- QR-ICU (NCT07660705)
- Testing
- QR Code-Based Digital Educational Video
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Intensive Care Medicine, ARDS
Change of Immune Cell of ARDS Patients：an Observational Study
To evaluate change of different immune cellsduring ARDS and its impact on prognosis.
- Trial name
- NCT02958748
- Testing
- taking blood sample
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Sepsis, Acute Kidney Injury Due to Sepsis
Microbiome and Enteric Signatures in Sepsis-associated Hepatorenal Injury
Sepsis is a major cause of morbidity and mortality in intensive care units. Sepsis-associated liver injury (SALI) and sepsis-associated acute kidney injury (S-AKI) are common complications associated with adverse clinical…
- Conditions
- Sepsis, Acute Kidney Injury Due to Sepsis, Gastrointestinal Microbiome, Sepsis-Associated Liver Injury
- Trial name
- MESH (NCT07735182)
- Where
- 6 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Critical Illness
Exploration of Investigating ICU Mobilisation With Vasoactive Drugs
There is a need to know more about the safety of mobilizing intensive care unit (ICU) patients who are receiving vasoactive drugs that support the heart and blood pressure.
- Trial name
- NCT03869541
- Testing
- Mobilization
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Education, Health
Simulation Training as a Tool to Decrease Occupational Stress in ICU Personnel
The purpose of the study is to check wether training mixed teams of physicians and nurses from intensive care units on patient simulators reduces stress in team members.
- Trial name
- NCT00232323
- Testing
- simulation training
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Competency-Based Education
Effect of a Competence Based Medical Education Programme on Training Quality in Intensive Care Medicine.
This study evaluates whether the implementation of a competency-based medical education program called CoBaTrICE (Competency Based Training program in Intensive Care in Europe) provides higher levels of competency in comparison…
- Trial name
- COBALIDATION (NCT04278976)
- Testing
- Implementation of CoBaTrICE
- Where
- 14 sites in Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Alvaro Castellanos Ortega
Sleep Deprivation, Depression
Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being.
- Trial name
- NCT00996320
- Testing
- Reduced work hour schedule
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Healthy
Effectiveness of an Intensive Intervention to Improve Physical Activity in Postmenopausal and Sedentary Women
This is a randomized clinical trial aimed at postmenopausal women aged 45 to 70 years old selected in urban primary care centers of two centers (Spain).
- Trial name
- NCT03872258
- Testing
- Control, Intervention group
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Drug Interaction
Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.
Drug drug interactions is frequent in critically ill patients due to polypharmacy, different drug groups and prolonged ICU or hospital stay
- Trial name
- NCT04078620
- Testing
- Survey for drug drug interactions on medscape and lexicomp applications
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Postoperative Cognitive Dysfunction
Retrospective Evaluation of POCD Data of Studies From KAI, Charité - Universitätsmedizin Berlin
Data on prevention of perioperative neurocognitive disorders (pNCDs) are limited. The purpose of this monocentric parallel - grouped observational registry is to collect study data from studies with pNCDs as primary or secondary…
- Trial name
- NCT02832193
- Where
- 2 sites in Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Education, Health
Simulation Training as a Tool for Teamwork Improvement in Multidisciplinary Intensive Care Team
The purpose of the study is to check whether training mixed teams of physicians and nurses from intensive care units on patient simulators improves teamwork within the teams.
- Trial name
- NCT00229411
- Testing
- simulation training
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Vasoplegia
Midodrine for the Early Liberation of Vasopressor Support in the ICU (LIBERATE Multi-Site)
Vasopressors are medications that are given intravenously to increase the blood pressure of patients with illnesses that cause dangerous blood pressure drops.
- Trial name
- NCT05058612
- Testing
- Midodrine
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Intensive Care Medicine, Acute Care Medical
Functional Incremental Stepping in Place Test (F-IST) Validation
The purpose of this multi-site prospective study is to assess validity of a new step test called Functional-Incremental Stepping-in-place- Test (F-IST) compared to gold-standard cardiopulmonary exercise testing (CPET) and to…
- Trial name
- F-IST (NCT06853236)
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirby Mayer
SARS-CoV-2, Coronavirus
Personalized Health Education Against the Health Damage of Novel Coronavirus (COVID-19) Outbreak in Hungary
The additional effect of personalized health education compared to general education following the internationally accepted principles will be evaluated in the prevention of the serious course of the novel coronavirus infection.
- Conditions
- SARS-CoV-2, Coronavirus, COVID-19, 2019-nCoV
- Trial name
- PROACTIVE-19 (NCT04321928)
- Testing
- Personalized health education, General health education
- Where
- Hungary
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Intensive Care
Drug Administration From Enteral Nutrition Tube
Enteral nutrition protocols are applied in patients who do not have gastrointestinal dysfunction but in whom oral feeding is contraindicated.
- Trial name
- NCT05790291
- Testing
- Checklist
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Emel Külekçi