Clinical trials: Intensive Care Unit Admission
Hypomagnesemia, Critical Illness
Hypomagnesemia and Its Clinical Outcome
Magnesium is an essential electrolyte involved in numerous physiological processes, including maintaining cellular integrity, regulating muscle tone, supporting cardiovascular function, and modulating immune responses.
- Conditions
- Hypomagnesemia, Critical Illness, Intensive Care Unit (ICU) Patients, Scoring Systems
- Trial name
- Hypogamnesamia (NCT07089004)
- Testing
- No intervention (observational study)
- Where
- Bangladesh
- Volunteers
- 112 people
- Sponsor
- Bangladesh Bioscience Research Group
Intensive Care Unit Acquired Weakness
Application of the Concept of Proprioceptive Neuromuscular Facilitation in Trunk Control in Patients Admitted to the ICU.
Muscle weakness acquired in the ICU (FAUTI) is related to the functional decline of patients admitted to an Intensive Care Unit (ICU).
- Trial name
- PNF (NCT07584564)
- Testing
- Proprioceptive Neuromuscular Facilitation (PNF), Standard physiotherapy
- Where
- Brazil
- Volunteers
- 58 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Patient Compliance
Lactate Level and Gastrointestinal Bleeding
Acute gastrointestinal bleeding is a common emergency with significant morbidity, mortality, and cost. Appropriate risk stratification of patients presenting with acute gastrointestinal bleeding aids in the triage of patients to…
- Trial name
- NCT04104425
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Assiut University
Vitamin D Deficiency
Emulated Study of Vitamin D Correction Vs Non-Correction
This is a single-site retrospective electronic chart review of Cooper Health System Inpatients and Outpatients from 2008 through 2023 aged eighteen years or older.
- Trial name
- NCT06366776
- Where
- United States
- Volunteers
- 9,000 people
- Sponsor
- The Cooper Health System
Infant Admitted to Neonatal Intensive Care Unit (NICU), Doula Support
Community-Partnered Doula Support for Neonatal Intensive Care Unit Families
The goal of this clinical trial is to learn if pairing families who have a baby in the Neonatal Intensive Care Unit with a community doula improves stress.
- Trial name
- NCT07437131
- Testing
- Enhanced doula support
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Intensive Care Unit (ICU) Admission
Biomarker Signature-Supported Antibiotic Treatment Decisions in ICU
The goal of this randomized clinical trial is to determine whether a biomarker-signature (BV) supported antibiotic treatment decision matrix can have a beneficial impact on antibiotic use and patient outcomes in an ICU population.
- Trial name
- BAST-ICU (NCT07481773)
- Testing
- Biomarker-signature supported antibiotic treatment recommendation, Clinical assessment for antibiotic treatment decision
- Where
- 4 sites in Canada
- Volunteers
- 1,200 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Intensive Care Admission
The Impact of Clinical Pharmacists Role in Transition of Care From Other Departments to Critical Care Units in Alexandria Main University Hospital.
Transition of care between hospital departments is an important step in patient care. Every patient may need to be transmitted either for case deterioration, improvement or interventions purposes.
- Trial name
- NCT06903572
- Testing
- the clinical pharmacists interventions about medication related information during transition of care
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Alexandria University
COVID-19
Assessment of Clinical Effects of Coenzyme Q10 Levels in COVID-19 Patients in Intensive Care Unit
The study will be done in Hacettepe University Anesthesiology and Reanimation Intensive Care Unit. The investigators will accept COVID-19 diagnosed or suspected patients to the ICU.
- Trial name
- NCT05058716
- Testing
- blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Hacettepe University
Cognitive Impairment, Apolipoprotein E, Deficiency or Defect of
Perioperative Research Into Memory, Genomics in the Intensive Therapy Unit: Alzheimer's
The current central dogma of long-term cognitive impairment after intensive care admission suggests an underlying neuroinflammatory dysregulation affecting neuronal function.
- Conditions
- Cognitive Impairment, Apolipoprotein E, Deficiency or Defect of, Critical Illness, Burns
- Trial name
- PRIMoGenITA (NCT03393130)
- Testing
- APOE genotyping
- Volunteers
- 150 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Adult Patient (Over 18 Yr-old) Admitted to the ICU for Acute Peritonitis
Evaluation of BD Glucan in Peritoneal Fluid for the Diagnosis of Fungal Peritonitis
Invasive candidiasis has a high mortality rate, around 40%. Outcome remains tightly linked to the time of treatment administration.
- Trial name
- PERICAND (NCT03469401)
- Testing
- Intervention
- Where
- France
- Volunteers
- 126 people
- Sponsor
- Hospices Civils de Lyon
Unexpected Hospital Mortality, Death, Sudden, Cardiac
Prevention of Serious Adverse Events in Acute Care Hospitals by Afferent Limb and Response Method Intervention - the ALARM Intervention Study.
1. Summary Growing evidence suggests that a significant proportion of in-hospital patient deaths occur after serious adverse events (SAE's).
- Conditions
- Unexpected Hospital Mortality, Death, Sudden, Cardiac, Unplanned Intensive Care Unit Admission
- Trial name
- ALARM (NCT01949025)
- Testing
- ALARM intervention
- Where
- Belgium
- Volunteers
- 69,656 people, healthy volunteers welcome
- Sponsor
- Universiteit Antwerpen
COVID-19
A Study to Evaluate Safety and Efficacy of Convalescent Methylene Blue Treated (MBT) Plasma From Donors Recovered From Coronavirus Disease 2019 (COVID-19)
The purpose of the study is to determine if Convalescent anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Methylene Blue Treated (MBT) plasma plus Standard Medical Treatment (SMT) can reduce all-cause mortality…
- Trial name
- NCT04547127
- Testing
- Convalescent anti-SARS-CoV-2 MBT Plasma, Standard Medical Treatment
- Where
- 12 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Instituto Grifols, S.A.
COVID-19, Critical Illness
Analysis of Mortality of Critically Ill Patients With COVID-19
The recent pandemic of the COVID-19 disease has caused a national health emergency due to its severity and the clinical and social consequences of the disease. Crude mortality in Spain is 9.2%.
- Conditions
- COVID-19, Critical Illness, Effectiveness, Outcome, Fatal
- Trial name
- NCT04379258
- Where
- Spain
- Volunteers
- 868 people
- Sponsor
- Hospital Universitario Getafe
Critically Ill Severe Bronchiolitis
Helmet Continuous Positive Airway Pressure Support for Severe Bronchiolitis in PICUs
Binary randomized peep level of Helmet CPAP (1-0). The first patient enrolled will be assign to treatment 1 (10 cmH2O peep level), independently from its BSS.
- Trial name
- NCT02977585
- Testing
- 10 cmH2O peep
- Where
- Italy
- Volunteers
- 126 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Acute Coronary Syndrome, Heart Failure
Impact of COVID19 Outbreak in Cardiac Acute Care
This registry will evaluate the impact of the COVID19 outbreak on Cardiac patients admitted in the Intensive Care Unit of the Pitie-Salpetriere Hospital in Paris, France
- Conditions
- Acute Coronary Syndrome, Heart Failure, COVID
- Trial name
- CCU-COVID19 (NCT04344912)
- Testing
- Data collection
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypoglycemia, Neonatal Hypoglycemia
Effects of a Hypoglycemia Protocol With Glucose Gel on Neonatal Intensive Care Unit (NICU) Admission
Evaluate if the implementation of a hypoglycemia protocol with glucose gel has reduced the NICU admission rate of neonates with low-acuity neonatal hypoglycemia.
- Trial name
- NCT04085978
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Pediatrix
Pediatric Patient (1m-21y), ICU Admission
Pediatric Intensive Care Units (ICUs) at Emory-Children's Center Glycemic Control: The PedETrol Trial
The primary goal of this project is to determine whether normalizing hyperglycemia is a safe approach to improve multisystem organ function in critically ill children requiring intensive care.
- Conditions
- Pediatric Patient (1m-21y), ICU Admission, Hyperglycemia
- Trial name
- PedETrol (NCT01116752)
- Testing
- Active Glycemic Control Strict (80-140mg/dL) vs. Conservative (190-220mg/dL) (with or without Continuous Glucose Monitoring)
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Indiana University
Low Birth Weight Among Neonates
Randomized, Controlled Trial of Kangaroo Mother Care in Increasing the Rate of Weight Gain Among Neonates
A randomized, controlled trial of Kangaroo Mother Care (KMC) to determine the effectiveness in increasing the rate of weight gain among low birth weight neonates.
- Trial name
- NCT02085382
- Testing
- Kangaroo Mother Care, Conventional Mother Care
- Where
- Philippines
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of the Philippines
Acute Neurological Injury, Emotional Distress
Building Resiliency in Dyads of Patients With an ANI Admitted to the Neuro-ICU and Their Informal Caregivers
The purpose of the present investigation is to test the efficacy of a brief (6 sessions) dyadic (patient and caregiver together) intervention to prevent chronic emotional distress in at risk dyads admitted to a Neuroscience…
- Trial name
- NCT05157880
- Testing
- Recovering Together
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Massachusetts General Hospital