Clinical trials: Interaction
Hepatitis C, HIV
Potential for Drug-drug Interactions Between Boceprevir and Etravirine in HIV/Hepatitis C Virus Negative Volunteers
The investigators believe that boceprevir's drug concentrations will be reduced when administered in combination with etravirine.
- Trial name
- NCT01427504
- Testing
- boceprevir; etravirine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Metabolic Syndrome
Prothrombotic Inflammatory Markers in Women With Metabolic Syndrome - Effect of Atorvastatin
Little is known regarding the association of individual components of the metabolic syndrome (MBS) and prothrombotic, inflammatory and preclinical cardiac structural and functional markers in women with this syndrome.
- Trial name
- PINK (NCT01785615)
- Testing
- Atorvastatin
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Climate Change, Interactive Digital-based Educational Program
Interactive Digital-based Educational Program and Climate Change
Nursing's climate action position may shift from a white and wealthy world to a more inclusive one. Nurses in Egypt and elsewhere have found resonance with this method of campaigning, pressing their employers to implement…
- Conditions
- Climate Change, Interactive Digital-based Educational Program, Rural Nurses
- Trial name
- NCT06196476
- Testing
- Interactive digital-based educational program
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Anxiety, Artificial Intelligence (AI)
Effect of Artificial Intelligence on Assessing Dental Anxiety in Children
The goal of this observational study was to evaluate an artificial intelligence-assisted projective method for assessing dental anxiety in young children and to understand how the first child-dentist interaction affected dental…
- Conditions
- Dental Anxiety, Artificial Intelligence (AI), Test Anxiety Scale
- Trial name
- NCT07387055
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Sümeyra Akkoç
Diabetes Mellitus, Type II
Bioequivalence Study for Acarbose / Metformin FDC
To establish the bioequivalence between Acarbose / Metformin FDC (50mg / 500mg) and loose combination of Acarbose (Glucobay) (50mg) and Metformin (Glucophage) (500mg).
- Trial name
- NCT01728740
- Testing
- Acarbose/Metformin FDC (BAY81-9783), Acarbose (Glucobay, BAYG5421), Metformin
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayer
Smoking Cessation
Pharmacological Aids for Interactive Smoking Cessation
There is an important need for effective smoking cessation programs that both (a) promote the effective use of pharmacological aids, such as nicotine replacement products and bupropion, and (b) provide cognitive-behavioral…
- Trial name
- NRT_2 (NCT02329249)
- Testing
- Smokefree Partners: 21 Days to Freedom, Wait-List Control
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Oregon Center for Applied Science, Inc.
Exposure to Environmental Pollution, Non-occupational
Interaction Effects of Temperature and Ozone
Purpose: The purpose of this protocol is to understand how individuals respond to the air pollutant ozone at elevated temperatures.
- Trial name
- TROPICOZ (NCT01981135)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Learning, Human-animal Interaction
Influence of Dogs on Learning in Children
In a randomised controlled cross-over study, the influence of interacting with a dog on children's learning performance is investigated.
- Trial name
- NCT02992626
- Testing
- Human-dog interaction, Stuffed toy dog
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Healthy
A Study of MK-8507 and Islatravir (MK-8591) in Healthy Adult Participants (MK-8507-016)
The main goals of this study are to learn what happens to Islatravir or MK-8507 in a person's body over time. Researchers will compare Islatravir given alone to Islatravir given with MK-8507.
- Trial name
- NCT06619678
- Testing
- MK-8507, Islatravir
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Healthy Participants
A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants
This study consists of 3 parts: Part A, Part B and Part C. This study will compare the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of AZD4144 with placebo in healthy participants, in Part A and Part B.
- Trial name
- NCT06491550
- Testing
- AZD4144- Part A, AZD4144- Part B, Rosuvastatin and Furosemide- Part C
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy
The Pharmacokinetic Interaction Between Amlodipine and Losartan
This clinical trial aims to assess the pharmacokinetic interaction between amlodipine and losartan in healthy male subjects.
- Trial name
- NCT03912285
- Testing
- Amlodipine10mg, Losartan potassium 100mg, Amlodipine plus Losartan
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Healthy
Drug-Drug Interaction Study: ASP2151 and Midazolam
CYP3A4 is involved in the metabolism of many drugs. So, it is important to assess in vivo the induction effect of ASP2151 on that enzyme to determine the extent of any possible drug interactions.
- Trial name
- NCT02403635
- Testing
- Midazolam, ASP2151
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Maruho Europe Limited
Healthy Participants
A Study of PF-07258669 In Healthy Adult Participants
Part A of this study is to evaluate safety, tolerability, and pharmacokinetics (PK) of PF-07258669 after administration of multiple ascending oral doses to healthy adult participants.
- Trial name
- NCT05113940
- Testing
- PF-07258669, Midazolam
- Where
- Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pfizer
Drug Drug Interaction
Fruquintinib CYP3A Inhibitor and Inducer Study
A study to assess the effect of itraconazole, a strong CYP3A inhibitor, and the effect of rifampin, a strong CYP3A inducer, on the pharmacokinetics of fruquintinib in healthy subjects.
- Trial name
- NCT04557397
- Testing
- Fruquintinib, Itraconazole, Rifampin
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hutchison Medipharma Limited
Interactive Voice Response (IVR)
Treatment Follow-up Study
This study will assess the effectiveness of a medication safety monitoring method utilizing interactive voice response technology for youth recently prescribed anti-depressant medication.
- Trial name
- PhaST (NCT00995696)
- Testing
- PhaST IVR Calls
- Where
- 2 sites in United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Oral Health
Interactive Video- and Game-Based Oral Health Education for 11-Year-Old Schoolchildren
The goal of this cluster randomised controlled trial is to learn if an interactive video- and game-based oral health education intervention helps improve oral health outcomes among 11-year-old schoolchildren in Pulau Pinang…
- Trial name
- NCT07097324
- Testing
- Video- and Game-Based Oral Health Education, Conventional Oral Health Talk
- Where
- Malaysia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Pain
A Study to Evaluate the Pharmacokinetic Drug-drug Interactions Between VX-548, Midazolam, and Digoxin
The purpose of this study is to evaluate the pharmacokinetics of midazolam and digoxin in the absence and presence of VX-548.
- Trial name
- NCT05541471
- Testing
- VX-548, Midazolam, Digoxin
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Healthy
Chatbot Intervention Effects on Resting-State Brain Function in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on resting-state brain function in college students with elevated anhedonia and depressive…
- Trial name
- NCT07665216
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Cerebral Palsy, Cerebral Palsy (CP)
Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
The overall goal of this study is to establish the clinical utility and accuracy of markerless motion captures systems for tracking therapy exercises and movement during game play. Specific aims are: 1.
- Trial name
- MOCAP (NCT07360171)
- Testing
- Validity Assessment of Sensors for Movement Tracking With Children/Youth With Diverse Neuromotor Abilities
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Drug Drug Interaction, Healthy
Pharmacokinetics of Omeprazole and Midazolam When Co-administered With ACT-1014-6470
A study on whether ACT-1014-6470 has an effect on how the body takes up, distributes and gets rid of omeprazole and midazolam in healthy male subjects
- Trial name
- NCT05123820
- Testing
- Treatment period A, Treatment period B
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.