Clinical trials: Intermittent Explosive Disorder
Intermittent Explosive Disorder
Pimavanserin and Aggression and Social Cognition.
The investigators are studying how certain drugs can reduce anger outbursts in people with anger problems. In this study the investigators seek to determine if a single 34 mg (two 17 mg tablets) oral dose of the 5-HT2a receptor…
- Trial name
- NCT05895513
- Testing
- Pimavanserin 34 mg
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Intermittent Explosive Disorder
Inflammatory Challenge in Human Aggression.
The goal of this clinical trial is to explore the differences in behavioral and cytokine response to a low dose infusion of endotoxin (vs.
- Trial name
- LPSS (NCT06665074)
- Testing
- Endotoxin (E. coli O:113, Reference Endotoxin)
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Intermittent Explosive Disorder
Effect of Nitrous Oxide on Aggression.
The goal of this experimental medicine clinical trial is to test the hypothesis that nitrous oxide inhalation will result in a change in neurocircuit function in healthy controls and in individuals with impulsive aggressive…
- Trial name
- NCT06118567
- Testing
- Nitrous oxide, Room Air
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anger, Intermittent Explosive Disorder
Maladaptive Anger Treatment
From a psychoevolutionary perspective, anger is a universal emotion that can serve the function of making us aware of wrongdoing and motivating us to undo/correct the wrongdoing.
- Conditions
- Anger, Intermittent Explosive Disorder, Emotional Distress, Aggression
- Trial name
- NCT06275607
- Testing
- Cognitive Behavioral Affective Therapy, Emotional Discussion
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
Alcohol Use Disorder, Intermittent Explosive Disorder
Neural Correlates During Alcohol Intoxication
Alcohol intoxication is responsible for a large proportion of violent crime/assault and personal injury in our society. While a number of variables have been associated with alcohol-related aggression, high trait aggression and…
- Trial name
- NCT06118580
- Testing
- Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Ohio State University