Clinical trials: Intermittent Hypoxia
Intermittent Hypoxia, Healthy Volunteers
Influence of Intermittent Hypoxia on Loop Gain in Healthy Subjects
Sleep apnoea-hypopnoea syndrome (SAHOS), which causes numerous comorbidities, particularly cardiovascular ones, is widespread worldwide today and incurs significant healthcare costs.
- Trial name
- HI-LOOP (NCT07409649)
- Testing
- Intermittent hypoxia, Normoxia
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Normoxia, Intermittent Moderate Hypoxia
Brain Connectivity and Corticospinal Excitability in Response to Moderate Hypoxia
Hypoxia, defined as a reduction in the availability of oxygen, induces significant physiological adaptations. While the deleterious effects of severe and chronic hypoxia are well documented, several studies indicate that moderate…
- Conditions
- Normoxia, Intermittent Moderate Hypoxia, Continuous Moderate Hypoxia
- Trial name
- NEUROXIE (NCT07516028)
- Testing
- Moderate hypoxia, Normoxia, Transcranial Magnetic Stimulation
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universite du Littoral Cote d'Opale
Intermittent Hypoxia, Respiratory Endurance
Effect of Intermittent Hypoxia on Ventilatory Endurance in Healthy Volunteers
Sleep apnoea syndrome is a common disorder responsible for poor sleep quality and repeated oxygen depletion in the blood. Patients suffering from this disease experience a reduction in their endurance, i.e.
- Trial name
- ENDUR-HYPOX (NCT06714435)
- Testing
- Intermittent hypoxia, Normoxia
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Intermittent Hypoxia, Exercise Recovery
CPOD Patient's Tolerance of Intermittent Exercise With Inter-exercise Recovery Under Normoxic Hypoxia
Exercise retraining improves the prognosis and quality of life of patients with chronic lung or circulatory diseases. However, exercise intolerance may be caused by excessive ventilatory.
- Conditions
- Intermittent Hypoxia, Exercise Recovery, Intermittent Exercise, Rating Exertion Perception
- Trial name
- HypoChronoPerf (NCT07072975)
- Testing
- Normobaric hypoxia, normoxic condition
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Apnea of Prematurity, Intermittent Hypoxia
Pilot Study to Evaluate Doses of Mechanical Stimulus on the Effectiveness of Preterm Breathing
The goal of this clinical trial is to compare, in healthy preterm babies, 9 doses of dorsal mechanical stimuli, in order to answer: if there is a dose of dorsal mechanical stimuli that improves the basal respiration.
- Trial name
- NCT06639581
- Testing
- 20 per minute stimulus, 30 per minute stimulus, 40 per minute stimulus
- Where
- Chile
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Intermittent Hypoxia, Normoxia
Intermittent Hypoxia and Balance Control
This study aims to determine the effect of acute mild intermittent hypoxia on ankle plantarflexor muscle output during balance regulation and walking in younger and older adults.
- Trial name
- NCT05463042
- Testing
- Intermittent Hypoxia
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Intermittent Hypoxia
Intermittent Hypoxia and Caffeine in Infants Born Preterm
Intermittent Hypoxia and Caffeine in Infants Born Preterm (ICAF) Our proposal will address the critical question: is persisting intermittent hypoxia (IH) in preterm infants associated with biochemical, structural, or functional…
- Trial name
- ICAF (NCT03321734)
- Testing
- Caffeine
- Where
- 15 sites in United States
- Volunteers
- 170 people
- Sponsor
- Children's National Research Institute
Intermittent Hypoxia
Effect of a Single Session of Intermittent Hypoxia on Hematological Variables
The purpose of the study is to determine the effect of a single exposure of intermittent hypoxia on erythropoietin levels and hemoglobin mass in young adults, older adults and patients with type 2 diabetes.
- Trial name
- NCT05898685
- Testing
- Intermittent hypoxia, Intermittent normoxia
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Intermittent Hypoxia
Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals
The objective of the present study is to determine whether intermittent hypoxia protects against ischemia-reperfusion injury in young and older healthy individuals.
- Trial name
- NCT05423470
- Testing
- Intermittent hypoxia, Intermittent normoxia
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Intermittent Hypoxia
Effects of Melatonin on Sleep, Ventilatory Control and Cognition at Altitude
Low oxygen at altitude causes pauses in breathing during sleep, called central sleep apnea. Central sleep apnea causes repeated awakenings and poor sleep.
- Trial name
- NCT03588676
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Robert L. Owens
Intermittent Hypoxia
Intermittent Hypoxia and Inspiratory Threshold Loading to Enhance Inspiratory Muscle Function
Rehabilitation approaches introduce a stimulus to a motor system, with the goal to enhance motor function to patients. For example, exposure to brief and intermittent episodes of mild hypoxia has shown to strengthen synaptic…
- Trial name
- NCT03029559
- Testing
- Intermittent Hypoxia, Inspiratory Threshold Loading
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Intermittent Hypoxemia, Apnea of Prematurity
Influence of Oxygen Target Range on Intermittent Hypoxemia in Preterm Infants
In this randomized crossover trial, preterm infants with intermittent hypoxemia and need for supplemental oxygen will be randomized to either Sequence of two different oxygen target ranges (low: 85-89%; high: 91-95%) for a total…
- Trial name
- NCT02743988
- Testing
- Oxygen
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- University of Ulm
Obstructive Sleep Apnea Syndrome, Endothelial Dysfunction
Oxidative Stress and Endothelial Dysfunction in Obstructive Sleep Apnea
Patients with sleep apnea syndrome have repeated apneic events that induce periodic hypoxia-reoxygenation, drawing away an overproduction of oxidants.
- Conditions
- Obstructive Sleep Apnea Syndrome, Endothelial Dysfunction, Oxidative Stress, Intermittent Hypoxia
- Trial name
- SOREVAS (NCT00646971)
- Testing
- CPAP device
- Where
- France
- Volunteers
- 11 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris