Clinical trials: Internal Carotid Artery Stenosis, open to volunteers
Internal Carotid Artery Stenosis
Safety and Efficacy of Carotid Artery Stenting Combined With Intermittent Hypoxia Intervention in Patients With Severe Internal Carotid Artery Stenosis
This study aims to explore the efficacy of Intermittent Hypoxia Treatment (IHT) in preventing peri-operative embolism-related microinfarcts among patients with severe internal carotid artery stenosis (ICAS) undergoing carotid…
- Trial name
- NCT07837011
- Testing
- intermittent hypoxia intervention, Carotid Artery Stenting (CAS), Standard Medical Therapy
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Capital Medical University
Stroke (CVA) or TIA, Carotid Artery Plaque
[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease
This clinical trial aims to evaluate whether [¹⁸F]AlF-OC PET/MRI can characterize and quantify inflammation in carotid atherosclerotic plaques.
- Conditions
- Stroke (CVA) or TIA, Carotid Artery Plaque, Atherosclerosis Cardiovascular Disease, Carotid Arteriosclerosis
- Trial name
- NCT07104487
- Testing
- [18F]AlF-OC
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Artery Stenosis
Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)
Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli during CAS and may offer therapeutic benefits through…
- Trial name
- NCT07462546
- Testing
- Transcranial Doppler
- Where
- China
- Volunteers
- 232 people
- Sponsor
- General Hospital of Shenyang Military Region
Carotid Artery Stenosis, Carotid Artery Stenting
Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS
About 20% of stroke causes are atherosclerotic strokes caused by carotid artery stenosis. In 2005, 92% of carotid artery interventions in the USA were performed in asymptomatic patients.
- Conditions
- Carotid Artery Stenosis, Carotid Artery Stenting, Stroke
- Trial name
- NOTICE-CAS (NCT06123767)
- Testing
- CAS + Intravascular measuring the pressure gradient, CAS (standard), Doppler ultrasonound of cephalic arteries
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Stroke, Acute, Carotid Stenosis
Endovascular Acute Stroke Intervention - Tandem OCclusion Trial
Patients with tandem occlusion or tandem lesion (TL), that is, stroke with an acute intracranial anterior circulation occlusion and an ipsilateral cervical ICA (c-ICA) high-grade stenosis or occlusion, constitute about 15-20% of…
- Conditions
- Stroke, Acute, Carotid Stenosis, Carotid Artery Diseases
- Trial name
- EASI-TOC (NCT04261478)
- Testing
- Carotid artery stenting, Antiplatelet Agents
- Where
- Canada
- Volunteers
- 458 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Intracranial Atherosclerosis, Stroke, Ischemic
Role of GLP1 RA Dulaglutide on Severe Intracranial Atherosclerosis
One important mechanism of action of GLP1 RA is the improvement in endothelial function, which may be evaluated by the assessment of cerebral vasodilatory reserve (CVR) in patients with severe ICAD.
- Trial name
- RADIANT (NCT07282041)
- Testing
- Dulaglutide
- Where
- Singapore
- Volunteers
- 130 people
- Sponsor
- National University of Singapore