Clinical trials: Internal Hernia
Gastroschisis
Early Feeds in Gastroschisis
This study aims to evaluate the feasibility of initiating early feeds in neonates with gastroschisis, a condition where infants are born with their intestines outside the body.
- Trial name
- GAIN (NCT06878950)
- Testing
- Early Feeding Protocol
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, Davis
Hydrocele, Inguinal Hernia
The Caudal Space in Children: Ultrasound Evaluation
Caudal anesthesia is commonly employed in pediatrics to produce postoperative analgesia in low abdominal or urologic surgery. An exact understanding of the anatomy of the sacral area including sacral hiatus and surrounding…
- Conditions
- Hydrocele, Inguinal Hernia, Hypospadia, Cryptorchidism
- Trial name
- NCT01896076
- Testing
- ultrasound evaluation of caudal space
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Yonsei University
Gastroschisis, Intestinal Ischemia
Regional Blood Saturation Levels in Gastroschisis
Gastroschisis is one of the most common neonatal surgical conditions, and is increasing in incidence. Postnatal bowel ischemia leading to necrosis, bowel loss and short-bowel syndrome, occurs in a few instances, with significant…
- Trial name
- NCT03533439
- Testing
- Near infrared spectroscopy
- Volunteers
- 19 people
- Sponsor
- NHS Lothian
Inguinal Hernia, Circumcision
Analgesia in Children Using Caudal Epidural Ropivacaine
Caudal epidural analgesia (caudal block)is used in standard pediatric anesthesia practice. It has been shown to be effective in managing postoperative pain in children undergoing abdominal and infraumbilical surgery (Tobias et al…
- Trial name
- NCT01494272
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Inguinal Hernia
Repair of Inguinal Hernia
The aim of this study is to compare the outcomes of open versus laparoscopic approaches for inguinal hernia surgery and provide evidence-based guidance to the selection of the most appropriate operative technique.
- Trial name
- NCT06514859
- Testing
- Laparoscopic repair of inguinal hernia, Open repair of inguinal hernia
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Children, Inguinal Hernia
Tamadol Wound Infiltration in Children Under Inguinal Hernioplasty
Tramadol is a centrally acting analgesic, is primarily Indicated for the treatment of acute pain, moderate to severe. The hernioplasty in children is an outpatient procedure, and the possibility of postoperative analgesia with…
- Trial name
- NCT01943760
- Testing
- tramadol, 0.9% saline
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Inguinal Hernia
The Addition of Hydromorphone to Local Anesthetics for the Repair of Inguinal Hernias in Elderly Patients
To compare the clinical and postoperative analgesic effects of hydromorphone combined with ropivacaine and ropivacaine alone in quadrangular muscle block for open inguinal hernia in elderly patients.
- Trial name
- NCT06218160
- Testing
- Hydromorphone combined with ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 63 people
- Sponsor
- Second Hospital of Jilin University
Inguinal Hernia
Mesh Fixation in Lichtenstein Hernioplasty
This is a prospective, randomized multi-centre study to find out most safe, feasible, painless and cost-effective mesh fixation method in inguinal hernia operation.
- Trial name
- NCT01592942
- Testing
- Histoacryl, Progrip, sutures (prolene 3-0)
- Where
- Finland
- Volunteers
- 650 people
- Sponsor
- Kuopio University Hospital
Hiatal Hernia With Gastroesophageal Reflux Disease
Comparison of Laparoscopic Nissen Fundoplication and Hill-Snow Repair for Hiatus Hernia With Endoscopic Evaluation
The goal of this clinical trial is to compare the clinical efficacy and safety of laparoscopic Nissen fundoplication (LNF) versus laparoscopic Hill-Snow repair (LHS) in the management of patients with congenital hiatus hernia, to…
- Trial name
- NCT07387042
- Testing
- Laparoscopic Hill-Snow repair, Laparoscopic Nissen Fundoplication
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Minia University
Hernia, Inguinal
Validation of a Subjective Rating Scale for Assessment of the Surgical Workspace in Laparoscopy
It is of great importance to obtain optimal surgical conditions for the surgeon in order to increase patient safety. The effect of different interventions on surgical conditions has been assessed by various surgeon-assessed…
- Trial name
- NCT02545270
- Testing
- Level of pneumoperitoneum 12-9-6 mmHg, Level of pneumoperitoneum 11-8-5 mmHg, Level of pneumoperitoneum 10-7-4 mmHg
- Where
- 2 sites in Denmark
- Volunteers
- 16 people
- Sponsor
- Herlev Hospital
Incisional Hernia, Abdominal Hernia
Hernia Sac Flap Coverage of Mesh in Bony-Edged Ventral Hernia Repair
This trial asks whether covering the inner, bowel-facing surface of a hernia mesh with a flap of the patient's own hernia sac improves healing after repair of a complex ventral (abdominal wall) hernia in which one edge of the…
- Conditions
- Incisional Hernia, Abdominal Hernia, Complex Ventral Hernia, Surgical Site Infection
- Trial name
- PERI-SAC (NCT07720154)
- Testing
- Sac-flap peritonealization of the mesh, Retromuscular (sublay) synthetic mesh repair
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Minia University
Seroma, Hernia, Inguinal
Use of Diathermy Versus Blunt Dissection in TEP for Inguinal Hernia
There is a long debate whether monopoloar or blunt dissection should be adopted in TEP to minimise the chance of seroma formation.
- Trial name
- NCT03665883
- Testing
- Monopolar energy, Blunt dissection
- Where
- China
- Volunteers
- 103 people
- Sponsor
- The University of Hong Kong
Postoperative Pain, Acute, Ventral Hernia
Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery
The purpose of this study is to assess whether listening to music during surgery has an effect on pain or anxiety after surgery.
- Conditions
- Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery
- Trial name
- NCT05374096
- Testing
- Patient-Chosen Music
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- The Cleveland Clinic
Inguinal Hernia
Antibiotic Prophylaxis in Mesh Repair of Inguinal Hernias
Inguinal hernia repairs is clean surgical procedures. However infection may be a concern when prosthetic materials are used. This prospective randomized study has been set to observe if antibiotic prohylaxis is of benefit in mesh…
- Trial name
- NCT01264003
- Testing
- sefazolin
- Volunteers
- 200 people
- Sponsor
- Diskapi Teaching and Research Hospital
Virtual Reality, Congenital Diaphragmatic Hernia
Virtual Reality and Congenital Diaphragmatic Hernia
The study has been designed to investigate the effect of 12 weeks of using virtual reality based exercises on pulmonary functions, exercise capacity, functional performance, and quality of life in children with…
- Conditions
- Virtual Reality, Congenital Diaphragmatic Hernia, Children
- Trial name
- NCT05612503
- Testing
- Traditional physical therapy program, Virtual reality-based exercises
- Where
- Saudi Arabia
- Volunteers
- 52 people
- Sponsor
- Qassim University
Colorectal Cancer, Adhesion
Mechanical Ileus in the Era of Minimally Invasive Colorectal Surgery
The present study was to investigate if the incidence, patterns and surgical outcomes of mechanical ileus have changed in the era of minimally invasive surgery (MIS).
- Trial name
- NCT05999162
- Testing
- Minimally invasive surgery
- Where
- Taiwan
- Volunteers
- 1,544 people
- Sponsor
- National Taiwan University Hospital
Congenital Diaphragmatic Hernia
Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)
The purpose of this study is to investigate the use of autologous umbilical cord blood (UCB) mononuclear cells to mitigate hypoxic neurologic injury among infants with high-risk congenital diaphragmatic hernia (CDH).
- Trial name
- NCT03526588
- Testing
- Autologous umbilical cord blood
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The University of Texas Health Science Center, Houston
Peripheral Nerve Block, Pain Management
Comparison of Postoperative Analgesic Effects of Quadro-iliac Plane Block and Transversus Abdominis Plane Blocks in Inguinal Hernia Surgery
Inguinal hernia repair is one of the most commonly performed surgical procedures worldwide. Despite being classified as a minor surgical intervention, moderate to severe postoperative pain is reported in approximately 60% of…
- Conditions
- Peripheral Nerve Block, Pain Management, Hernia, Inguinal
- Trial name
- NCT07442188
- Testing
- TAPB, QIPB
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Congenital Diaphragmatic Hernia
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH
Congenital diaphragmatic hernia (CDH) occurs when the diaphragm fails to fully fuse and leaves a portal through which abdominal structures can migrate into the thorax.
- Trial name
- NCT03980717
- Testing
- Goldbal Detachable Balloon and delivery microcatheter
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Michael A Belfort
Enterocolitis, Necrotizing, Atresia; Bowel
Timing of Stoma Closure in Neonates
Some babies require emergency surgery on their tummy in the first few months of life. This is most commonly because they were born prematurely and developed a bowel problem (called NEC) or a blockage of the bowel.
- Conditions
- Enterocolitis, Necrotizing, Atresia; Bowel, Gastroschisis, Meconium Ileus
- Trial name
- ToSCiN (NCT04713579)
- Testing
- No intervention - observational study
- Where
- United Kingdom
- Volunteers
- 56 people
- Sponsor
- Manchester University NHS Foundation Trust