Clinical trials: Internal Limiting Membrane
Retinal Detachment, Proliferative Vitreoretinopathy
Internal Limiting Membrane Peeling in Retinal Detachment Surgery
Despite advances in surgical techniques over the recent decades, proliferative vitreoretinopathy (PVR) remains the main obstacle to successful rhegmatogenous retinal detachment (RRD) repair, accounting for nearly 75% of all…
- Trial name
- IMPURITY (NCT05538156)
- Testing
- Control group, Intervention group
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Ophthalmopathy
Single Superior ILM/ERM Flap for the FTMH.
In this study, the investigators will make the only upper flap either from the internal limiting membrane or from the epiretinal membrane to cover the full thickness macular hole.
- Trial name
- NCT05494242
- Testing
- Surgical intervention
- Where
- Iraq
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Omer Othman Abdullah
Epiretinal Membrane, Vitreomacular Traction
Comparison of Two Techniques for Epiretinal or Internal Limiting Membrane Peel
Epiretinal membranes (ERM) are cellular membranes on the surface of the retina that result in distortion of the vision (metamorphopsia), and decreased best-corrected visual acuity.
- Trial name
- NCT00892619
- Testing
- using ILM forceps alone, Breaking and peeling with end-grasping forceps
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael E. DeBakey VA Medical Center
Macula Hole
Macular Hole Surgery With Temporal Inverted Internal Limiting Membrane Flap (MARTIAL)
Since 1991, idiopathic macular holes (MH) can benefit from an effective treatment initially involving pars plana vitrectomy, stripping of epiretinal membranes and intraocular gas tamponade followed by facedown positioning.
- Trial name
- MARTIAL (NCT03287102)
- Testing
- Macular hole surgery
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Epiretinal Membrane
Randomized Trial Comparing Epiretinal Membrane Surgery With and Without Internal Limiting Membrane Removal
Macular epiretinal membrane (ERM) is a semitranslucent, avascular, fibrocellular membrane on the inner surface along the internal limiting membrane (ILM) of the retina.
- Trial name
- NCT01532765
- Testing
- Pars plana vitrectomy and epiretinal membrane peel, ILM peel assisted by ICG, CE-IOL
- Where
- 3 sites in Canada
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre