Clinical trials: Interstitial Cystitis, Chronic
Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with…
- Conditions
- Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis, Bladder Pain Syndrome, Chronic Prostatitis
- Trial name
- EPPIC (NCT05127616)
- Testing
- Minimal Contact-Cognitive Behavior Therapy, Patient Education/Support
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- State University of New York at Buffalo
Interstitial Cystitis, Chronic Interstitial Cystitis
Investigation of PEMF Therapy for Female Patients With IC/BPS
The purpose of this study is to gather information about the safety and effectiveness of the non-pharmacological (non-drug), non-invasive treatment known as low-frequency pulsed electromagnetic field (PEMF) therapy.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT05149573
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis and Bladder Pain Syndrome
Learning to THRIVE (L2T) Program Pilot
This pilot study evaluated the feasibility and potential effects of Learning to THRIVE (L2T), a six-week online educational self-management program for adults who self-identified as women or female and had interstitial…
- Trial name
- L2T (NCT07797010)
- Testing
- Learning to THRIVE (L2T) Program
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Indianapolis
Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic
Evaluation of Hyivy Floora in Managing Interstitial Cystitis/Bladder Pain Syndrome/High-tone Pelvic Floor Dysfunction
The purpose of this study is to test the safety and effectiveness of the Floora Pelvic Rehabilitation Vaginal Dilator in females with Interstitial Cystitis/ Bladder pain Syndrome (IC/BPS) and High-tome Pelvic Floor Dysfunction…
- Conditions
- Interstitial Cystitis/Painful Bladder Syndrome, Interstitial Cystitis, Chronic, High Tone Pelvic Floor Dysfunction
- Trial name
- NCT07038512
- Testing
- Floora Pelvic Rehabilitation Vaginal Dilator
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Chronic Interstitial Cystitis
Safety and Efficacy of Aloe Vera in the Management of the Symptoms of Interstitial Cystitis
The purpose of this study is to assess the safety and efficacy of super-concentrated, freeze-dried aloe vera capsules for treatment of interstitial cystitis.
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT04734106
- Testing
- Desert Harvest Aloe Vera Capsules
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Chronic Interstitial Cystitis
Efficacy of Pulsed Electromagnetic Field and Heparin/Bupivacaine Instillations
The objective of this study is to test the idea that Pulsed Electromagnetic Field (PEMF) therapy will serve as a safe therapeutic modality that can effectively be administered simultaneously with bladder instillations of a…
- Conditions
- Interstitial Cystitis, Chronic Interstitial Cystitis, Bladder Pain Syndrome
- Trial name
- NCT06013449
- Testing
- Pulsed Electromagnetic Field (PEMF) Device
- Sponsor
- Wake Forest University Health Sciences
Bladder Pain Syndrome, Chronic Pelvic Nociplastic Pain
Venlafaxine Combined With Education and Behavioral Intervention for Bladder Pain Syndrome
This study aims to compare two treatment plans for adults with bladder pain syndrome (also called interstitial cystitis), a disease that causes long-lasting bladder pain, frequent urination and urgent need to pee.
- Conditions
- Bladder Pain Syndrome, Chronic Pelvic Nociplastic Pain, Interstitial Cystitis
- Trial name
- VEN-BPS (NCT07698626)
- Testing
- Venlafaxine oral tablet combined with Education and Behavioral Modification Program (EBMP), Education and Behavioral Modification Program (EBMP) only
- Volunteers
- 140 people
- Sponsor
- Beijing Tiantan Hospital
Cystitis, Interstitial, Chronic Pain
Safety and Preliminary Efficacy of Endoscopic Submucosal Injection of Hyaluronic Acid Into the Bladder Wall in Patients With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS)
The goal of this pilot clinical trial is to learn if injecting hyaluronic acid into the bladder wall is safe and if it works to reduce pain and urinary frequency in people with interstitial cystitis (IC), also called bladder pain…
- Trial name
- HA-IC/BPSPilot (NCT07658118)
- Testing
- Hyaluronic Acid (HA)
- Volunteers
- 15 people
- Sponsor
- Sverdlovsk Regional Clinical Hospital No.1
Interstitial Cystitis, Bladder Pain Syndrome
Motor Cortical Neuromodulation in Women With Interstitial Cystitis/Bladder Pain Syndrome
Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) is a common, chronic, and debilitating condition in women. Preliminary evidence suggests that IC/BPS pain can be reduced applying non-invasive repetitive transcranial magnetic…
- Trial name
- IcBrainStim (NCT04734847)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Southern California
Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS)
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition with several causes of which some remain unknown. It is believed that some types of CP may be genetic or passed down (inherited) from one generation to the…
- Conditions
- Chronic Prostatitis (CP), Chronic Pelvic Pain Syndrome (CPPS), Painful Bladder Syndrome (PBS), Benign Frequency Syndrome (BFS)
- Trial name
- CP/CPPS (NCT00499317)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Boston Children's Hospital
Vestibulodynia, Temporomandibular Disorder
Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments
Vestibulodynia (VBD) is a complex chronic vulvar pain condition that impairs the psychological, physical, and sexual health of 1 in 6 reproductive aged women in the United States.
- Conditions
- Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome
- Trial name
- NCT03844412
- Testing
- 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline
- Where
- 2 sites in United States
- Volunteers
- 209 people
- Sponsor
- Duke University
IC, Interstitial Cystitis and Bladder Pain Syndrome
The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis Without Hunner's Lesions.
To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis and the prevention of secondary bladder shrinkage with a decrease in its volume.
- Conditions
- IC, Interstitial Cystitis and Bladder Pain Syndrome, Interstitial Cystitis, Chronic
- Trial name
- NCT07391306
- Testing
- Neovasculgen®
- Where
- Russia
- Volunteers
- 180 people
- Sponsor
- JSC NextGen
Chronic Interstitial Cystitis, Bladder Pain Syndrome
Pain Type and Interstitial Cystitis/Bladder Pain Syndrome Treatment
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a severe pain condition affecting 3-8 million people in the United States lacking treatments that work.
- Conditions
- Chronic Interstitial Cystitis, Bladder Pain Syndrome, Painful Bladder Syndrome, Cystitis, Interstitial
- Trial name
- NCT06299683
- Testing
- Psychosocial Treatment, Pelvic Floor Physical Therapy
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Vanderbilt University Medical Center
Bladder Cancer, Prostate Cancer
Medtronic Hugo™ Robotic Assisted Surgery (RAS) System in Urologic Surgery (Expand URO)
This study will evaluate the safety and performance of the Medtronic Hugo™ RAS System when used for urologic RAS procedures.
- Conditions
- Bladder Cancer, Prostate Cancer, Kidney Cancer, Pelvic Tumor
- Trial name
- NCT05696444
- Testing
- RAS Prostatectomy, RAS Cystectomy, RAS Nephrectomy
- Where
- 6 sites in United States
- Volunteers
- 144 people
- Sponsor
- Medtronic - MITG
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Interstitial Cystitis, Chronic Pain
A Novel Medical System for Quantitative Diagnosis and Personalized Precision Botulinum Neurotoxin Injection in Chronic Pelvic Pain Management
The purpose of this study is to evaluate if it is possible to use intravaginal high-density surface electromyography to guide Botulinum neurotoxin (BoNT) injection to treat pelvic floor muscle overactivity that complicates…
- Conditions
- Interstitial Cystitis, Chronic Pain, Pelvic Floor; Relaxation, Pelvic Floor Disorders
- Trial name
- NCT05062902
- Testing
- High Density Surface Electromyographic, precision botulinum neurotoxin injection guidance medical device, Botulinum Neurotoxin
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- HillMed Inc.
Chronic Interstitial Cystitis
Pentosan Polysulfate Treatment's Effectiveness
To examine the relationship between symptoms and quality of life before and after oral pentosan polysulfate (PPS) treatment in cases diagnosed with interstitial cystitis/painful bladder syndrome (IC/BPS).
- Trial name
- NCT05744908
- Testing
- Pentosan Polysulphate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hisar Intercontinental Hospital
Interstitial Cystitis, Chronic, Overactive Bladder Syndrome
Real-life Clinical Experience With Ialuadapter Study
A retrospective study from a single center was performed. Quantitative and qualitative data was obtained on the use of the syringe adapter (IALUADAPTER®) in 61 patients with IC/BPS (n=48), rUTI (n=6) and mixed /other diagnoses…
- Conditions
- Interstitial Cystitis, Chronic, Overactive Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- Ialuadapter (NCT06540248)
- Testing
- Ialuadapter
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- Radboud University Medical Center
Interstitial Cystitis, Bladder Pain Syndrome
Auricular Acupressure Therapy for Patients With IC/BPS
The purpose of this study is to determine the feasibility of administering auricular acupressure for patients with interstitial cystitis/bladder pain syndrome (IC/BPS), and evaluating the efficacy of auricular acupressure to…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Urologic Diseases, Chronic Pain
- Trial name
- IC/BPS (NCT05857020)
- Testing
- Auricular Acupressure
- Sponsor
- Wake Forest University Health Sciences
Interstitial Cystitis, Chronic Prostatitis
Microbiomes of Pelvic Pain
This research study seeks to provide more insight as to how the microbiome affects or is affected by conditions causing chronic pelvic pain such as Interstitial Cystitis (IC), Chronic Prostatitis/Chronic Pelvic Pain Syndrome…
- Conditions
- Interstitial Cystitis, Chronic Prostatitis, Chronic Pelvic Pain Syndrome, Lower Urinary Tract Symptoms
- Trial name
- NCT01738464
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Northwestern University