Clinical trials: Interventional；
Cancer, Psychological Distress
Support and Healing Intervention for Adolescents With a Parent Diagnosed With Cancer (SHINE)
e purpose of this study is to develop and evaluate SHINE (Support and Healing Intervention for Navigating Parental Cancer Experiences), a family-centered program designed to support adolescents whose parent has been diagnosed…
- Conditions
- Cancer, Psychological Distress, Adaptation, Psychological
- Trial name
- SHINE (NCT07751185)
- Testing
- SHINE Psychosocial Intervention, Usual Supportive Care
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Myocardial Infarction
Safety and Feasibility of Using a Single Transradial Guiding Catheter for Primary PCI
The Rapid Trial is a randomized-controlled trial proposed to test the hypothesis that using a single guiding catheter for left and right coronary angiography and intervention in patients with ST elevation myocardial infarction…
- Trial name
- RAPID (NCT01759043)
- Testing
- guiding catheter, diagnostic catheter
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Beijing Luhe Hospital
Down Syndrome, Trisomy 21
JASPER Intervention in Down Syndrome
The goal of this study is to determine whether JASPER (Joint Attention, Symbolic Play, Engagement, Regulation), which is an intensive, targeted early behavioral intervention focused on a developmentally based approach for…
- Trial name
- NCT03653143
- Testing
- JASPER
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Boston Children's Hospital
Colonic Diseases, Functional
Adequacy of Anaesthesia for Colonoscopic Procedures
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively and its influence on…
- Trial name
- AoAColon (NCT03922815)
- Testing
- rescue fentanyl, rescue propofol
- Where
- Poland
- Volunteers
- 158 people
- Sponsor
- Medical University of Silesia
Acute Myocardial Infarction
Stellate Ganglion Morphine Infiltration on Myocardial Ischemia-Reperfusion Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion injury in AMI patients.
- Trial name
- tSGM-AMI (NCT06947135)
- Testing
- Morphine
- Where
- 3 sites in China
- Volunteers
- 166 people
- Sponsor
- The Second Hospital of Anhui Medical University
Geriatric Cancer Patients
A Chatbot-Powered G8 Screening Intervention to Facilitate Referrals to a Comprehensive Geriatric Assessment Among Older Adults With Cancer
In this prospective quality improvement study, we will develop and evaluate the feasibility and acceptability of an online patient self-reported G8 screening tool which will allow us to efficiently identify G8 positive older…
- Trial name
- NCT05535140
- Testing
- G8 Screening Tool
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Thomas Jefferson University
Family Conflict, Marital Conflict
Families of Youth with Developmental Disabilities: a Theory-Based Intervention
This study is designed to evaluate a preventive intervention program designed to support families (parents and typically developing adolescent siblings) that include a child with an intellectual and/or developmental disability.
- Conditions
- Family Conflict, Marital Conflict, Communication
- Trial name
- NCT03495440
- Testing
- Center Sessions, At-home
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Notre Dame
Chronic Kidney Diseases, Metabolic Syndrome
Theory-based Health Behaviour Change Intervention in Patients of Metabolic Syndrome With Chronic Kidney Disease
The pilot study will adopt a 2-arm, pretest-posttest, and assessor-blind randomized controlled trial design to examine the feasibility and acceptability of a theory-based health behaviour change intervention and examine its…
- Trial name
- NCT06527768
- Testing
- Theory-based health behaviour change interventio
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Social Anxiety
Variations of Anonymity, Transparency, and Efficacy in Digital Health Applications
Social Anxiety Disorder (SAD) is one of the most widespread mental illnesses and it has previously been shown that online therapy and online self-help tools such as the one investigated in this study can be successful in reducing…
- Trial name
- PRIVATE (NCT06465589)
- Testing
- JOURNeY anonymous, JOURNeY standard
- Where
- Switzerland
- Volunteers
- 452 people
- Sponsor
- University of Bern
Post-Traumatic Stress Disorder
Healing Touch & Guided Imagery for Posttraumatic Stress Disorder Symptoms
This is a randomized controlled 2 year trial at Camp Pendleton, CA to determine whether a complementary medicine intervention (Healing Touch with Guided Imagery, HT+GI) reduces Posttraumatic Stress Disorder (PTSD) symptoms as…
- Trial name
- NCT01348750
- Testing
- Healing Touch & Guided Imagery
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Scripps Center for Integrative Medicine
Lung Cancer
Telephone Support Program for Lung Cancer Patients and Their Family Caregivers
The goal of this project is to examine the physical and psychological health benefits of a novel, telephone-delivered symptom management intervention for advanced lung cancer patients and their family caregivers.
- Trial name
- NCT01993550
- Testing
- Telephone counseling, Education
- Where
- 3 sites in United States
- Volunteers
- 262 people
- Sponsor
- Indiana University
Exercise
Active Play Intervention for Preschoolers
The goal of this randomized clinical trial is to examine the effects of a planned movement in preschool-aged children. The main question is to determine What are the effects of a planned movement program on physical activity…
- Trial name
- Active Play (NCT05744791)
- Testing
- Active Play planned movement program
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Auburn University
Mental Health Issue
Mindfulness, Compassion and Self-compassion
Teachers in Hong Kong are susceptible to professional stress and its associated psychosomatic illnesses. To enhance teachers' well-being, mindfulness training is conducted in local schools.
- Trial name
- NCT05046691
- Testing
- 8-week mindfulness program
- Where
- Hong Kong
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Congenital Heart Disease in Children
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
The incidence of moderate to severe congenital heart disease (CHD) in the United States is estimated to be 6 per 1000 live-born full term infants.
- Trial name
- NCT04604418
- Testing
- No intervention. It is observational
- Where
- 10 sites in United States, Canada
- Volunteers
- 10,000 people
- Sponsor
- Boston Children's Hospital
HIV/AIDS
An mHealth Intervention to Improve Outcomes for Women With HIV/AIDS
The purpose of this study is: 1. To develop a new mobile health (mHealth) system that will send text messages to remind both pregnant and non-pregnant women with HIV to adhere to their treatment plan (like keeping appointments…
- Trial name
- NCT03738410
- Testing
- Mobile Health Messaging application, Standard of Care Treatment
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Bladder Pain Syndrome, Interstitial Cystitis
Hypnosis for Bladder Pain Syndrome
This is a pilot randomized control trial of 30 women with interstitial cystitis/bladder pain syndrome to determine the feasibility of delivering a hypnosis intervention or usual care on bladder pain (primary outcome) and cerebral…
- Trial name
- NCT04010513
- Testing
- Hypnosis, Standard of Care
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Pennsylvania
Kidney Cancer
Perioperative Ursodeoxycholic Acid for Renal Protection in Adults Undergoing Partial Nephrectomy for Renal Tumors
The goal of this clinical trial is to learn if ursodeoxycholic acid, also called UDCA, can help protect kidney function in adults undergoing partial nephrectomy for kidney tumors.
- Trial name
- PURIFY (NCT07672860)
- Testing
- UDCA (Ursodeoxycholic acid)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Jinling Hospital, China
Cognitive Decline
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Singapore's rising dementia incidence with an ageing population presents an urgent need for effective interventions that delay or prevent cognitive decline.
- Trial name
- ADL+ 2 (NCT07141160)
- Testing
- Combined: Mobile app + 6WELLS, Remote mobile based app
- Where
- Singapore
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
BPG Intervention, Control
Neurodevelopmental Assessment of Children in Uganda and Malawi Using a Software Package
The investigators will use Brain Power Games as a neurocognitive "stress test" or medical "challenge" test, in order to evaluate or improve brain/behavior functional integrity in HIV-affected children.
- Trial name
- NCT03878147
- Testing
- Cognitive Games Training
- Where
- 2 sites in Malawi, Uganda
- Volunteers
- 599 people
- Sponsor
- Michigan State University
SARS-CoV Infection, Covid19
'4C' Intervention to Reduce SARS-CoV-2 (Covid-19) Transmission
Nursing homes have long faced special challenges in implementing effective infection prevention programs, including limited resources and diagnostic challenges in a frail functionally disabled long-stay population.
- Trial name
- NCT04739449
- Testing
- Coaching, Cleaning, Communication, Collaboration
- Sponsor
- University of Michigan