Clinical trials: Interventional
Acute Anal Fissure
Effectiveness of Anal Enlargement by Dilators as a Therapeutic Physical Tool in Acute Anal Fissure
The treatment of anal fissure is mainly surgical. There are complications to this treatment, including damage to the inner anal sphincter and the appearance of fecal incontinence.
- Trial name
- NCT04828889
- Testing
- Anal dilators, lateral internal sphincterotomy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infantile Colic
Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
The study is conducted to examine the safety and efficacy of a new infant formula and its effects on the gastrointestinal tolerance in infants suffering from colic.
- Trial name
- Coco (NCT01721850)
- Testing
- control formula, intervention formula 1, intervention formula 2
- Where
- 18 sites in Germany, Italy
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Smoking Cessation, Smoking Behaviors
ACT Lung Health Intervention: Phase Two
This study aims to test a counseling and educational program designed to improve lung health through smoking cessation for Chinese and Korean American smokers at high risk for lung cancer.
- Conditions
- Smoking Cessation, Smoking Behaviors, Smoking, Tobacco, Smoking, Cigarette
- Trial name
- NCT06945120
- Testing
- ACT Lung Health Intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Quality of Life, Physical Activity
The Effectiveness of an Online Exercise Program on Well-being of Postpartum Women
The aim of this quasi-experimental study was to assess the effectiveness of a 6-week online exercise program on self-assessed quality of life (QoL), physical activity (PA), and dysfunctions of pelvic floor muscles of postpartum…
- Conditions
- Quality of Life, Physical Activity, Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT06268782
- Testing
- Rehabilitate your core
- Where
- Finland
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Turku
Violence in Adolescence, Domestic Violence
Engaging Together for Healthy Relationships
The goal of this pilot randomized clinical trial is to assess feasibility and acceptability of a brief parent-adolescent dating violence prevention intervention (Engaging Together for Healthy Relationships; ETHR) delivered in…
- Trial name
- ETHR (NCT05880979)
- Testing
- Engaging Together for Healthy Relationships, Regular well child care
- Where
- 2 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
HIV/AIDS
Acceptability, Feasibility and Preliminary Impact of OurPlan, an mHealth HIV Prevention Intervention for Male Couples
The study will evaluate the use and preliminary impact of an mHealth app for improving sexual health outcome measures among male couples by assessing whether exposure and use of the app results in improvements in participants and…
- Trial name
- OurPlan (NCT04836091)
- Testing
- Waitlist, Intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Florida International University
Insomnia
SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid
The objective of this study is to compare the efficacy of a sleep intervention on improving cognitive function in older adults with symptoms of insomnia, determine the association between change in sleep measures and change in…
- Trial name
- NCT03954210
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Sleep and Lifestyle Education
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Functional Gastrointestinal Disorders
Prevalence of FODMAP Intolerance and JHS in FGID and Association With Microbiome, Dyssynergic Defecation and Dietary Intervention
Irritable bowel syndrome (IBS) is a disorder of gastrointestinal function characterized by abdominal symptoms and pain associated with alterations in bowel habit.
- Trial name
- PreDiMi (NCT03460613)
- Testing
- FODMAP diet
- Where
- Switzerland
- Volunteers
- 498 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Dental Fear, Anesthesia, Local
Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children
Dental Fear and Anxiety (DFA) are at higher levels among children and often leads to avoidance of dental treatment. Negative experiences in the early years such as experience of pain during injections, fillings, or extractions…
- Conditions
- Dental Fear, Anesthesia, Local, Pediatric Dentistry
- Trial name
- NCT03779659
- Testing
- Synapse TENS device, Topical anesthetic gel
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston University
Postpartum Depression, Psychoeducation
Psychoeducational Intervention to Reduce Depressive Symptoms and Strengthen Mother-Infant Bonding
The study aims to evaluate the effectiveness of a psychoeducational intervention designed within the framework of the Watson Human Caring Model in reducing postpartum depressive symptoms and creating a stronger mother-infant…
- Conditions
- Postpartum Depression, Psychoeducation, Mother-Infant Interaction
- Trial name
- NCT07062159
- Testing
- the psychoeducation intervention program, routine care
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Yasemin Ozhuner
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Breast Cancer
Physical Activity and Breast Cancer Risk in Postmenopausal Women:the SHAPE Study
Purpose of the SHAPE study is to examine the effects of an 1-year exercise programme on endogenous hormone levels associated with breast cancer among sedentary postmenopausal women and whether a decrease in intra-abdominal fat is…
- Trial name
- NCT00359060
- Testing
- Physical activity
- Where
- Netherlands
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Attention Deficit Hyperactivity Disorder
Cognitive Behavioral Therapy for Adolescents With Attention-Deficit / Hyperactivity Disorder
Attention Deficit/ Hyperactivity Disorder (ADHD) is a common childhood psychiatric condition, which often persists into adolescence.
- Trial name
- NCT02566824
- Testing
- Cognitive Behavioural & Skills Training, Supportive Group Therapy, Treatment as Usual - community resources
- Where
- Canada
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Post-operative Nausea and Vomiting, Laparoscopic Sleeve Gastrectomy
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
Bariatric surgery remains the most effective therapy for obesity. Postoperative nausea and vomiting (PONV) are commonly reported following bariatric surgery.
- Trial name
- NCT03435003
- Testing
- Aprepitant 80 mg Oral Capsule, scopolamine transdermal, Total intravenous anesthesia
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Elderly
Objective Assessment and Promotion of Physical Activity in Elderly
The purpose of the present study is to evaluate the short-term and long-term effects of a cycle ergometer program on physical activity and physical fitness in elderly (65+).
- Trial name
- NCT01748461
- Testing
- Structured intervention, Coach intervention
- Where
- Belgium
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Breast Feeding, Exclusive
Evaluation of a Health Mediation Program in the Maternity Ward.
The first months of life are considered a critical period that has a lasting impact on a child's future health. Breastfeeding is one of the fundamental factors contributing to healthy growth in children.
- Trial name
- MédiMAT (NCT07806942)
- Testing
- postpartum breastfeeding support from a health mediator, routine health care without health mediation
- Where
- French Guiana
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Cayenne
Glucose Metabolism Disorders
Continuous Glucose Monitoring During Diets That Differ in Glycemic Load
This study test whether a Continuous Glucose Monitor can pickup differences in glucose (in the interstitial fluid) during a dietary intervention using meals with either a high with a low glycemic load.
- Trial name
- GLOW (NCT02926118)
- Testing
- Low glycemic load, High glycemic load
- Where
- Netherlands
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Breathing Exercises, PROGRESSIVE MUSCLE RELAXATION EXERCISES
THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM
This non-randomized controlled study evaluates a 10-week breathing and myofascial release program in university athletes. The intervention group receives structured training, while the control group receives only an informational…
- Conditions
- Breathing Exercises, PROGRESSIVE MUSCLE RELAXATION EXERCISES, Psychological Well-being
- Trial name
- NCT07553546
- Testing
- Integrated Breathing-Myofascial Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Marmara University
Alcohol Drinking
Effectiveness of a Peer-led Program to Prevent Alcohol Consumption.
The goal of this Randomized clinical trial is to evaluate the effectiveness of a peer-led intervention to prevent alcohol consumption in university students.
- Trial name
- NCT05639374
- Testing
- BASICS_HealthyClassroom
- Where
- Spain
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
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