Clinical trials: Interventional
Emotional Adjustment, Aids/Hiv Problem
Resilience-based Psychosocial Intervention Among Children Affected by HIV/AIDS
Parental illness and death from HIV/AIDS has a profound and lasting impact on a child's psychosocial well-being, potentially challenging the basic needs for survival and compromising the child's future.
- Trial name
- NCT04653441
- Testing
- Child-Caregiver-Advocacy-Resilience [ChildCARE] intervention
- Where
- United States
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Myopia ≤ -6 Diopters or Myopic Astigmatism ≤ -4 Diopters
Outcomes of a New Trans-epithelial Photorefractive Keratectomy (Streamlight PRK) Compared to Conventional PRK Procedures
Photorefractive keratectomy (PRK) involves mechanical or alcohol assisted debridement of the epithelium that leads to potential basement membrane (BM) injury ,with resultant more significant haze and pain compared to laser…
- Trial name
- NCT04710082
- Testing
- Photorefractive keratectomy (PRK)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Prevention
An Acceptance Based PrEP Intervention to Engage Young Black MSM in the South
Investigators will use a generalized framework for the adaptation of EBIs to inform the development of a brief Acceptance and Commitment Therapy (ACT)-based culturally appropriate pre-exposure prophylaxis (PrEP) intervention…
- Trial name
- NCT05087680
- Testing
- ACTPrEP, Enhanced Standard of Care
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Colo-rectal Cancer, Polyp of Colon
Computer Aided Detection of Polyps During Colonoscopy Procedures
The focus of the study is to evaluate impact on Adenomas Per Colonoscopy (APC) with a Computer Aided Detection (CAD) software assisting the gastroenterologist during a colonoscopy procedure.
- Conditions
- Colo-rectal Cancer, Polyp of Colon, Adenomatous Polyps
- Trial name
- NCT04195646
- Testing
- EndoVigilant CAD Software
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- EndoVigilant Inc
Oral Health
Maternal Oral Health Educational Intervention to Improve Knowledge, Practice and Dental Service Utilization
This research follows a mixed-method exploratory sequential design. It will take place at the Antenatal and Dental Outpatient Departments (OPD) of Dow University of Health Sciences (Ojha Campus) in Karachi.
- Trial name
- CODE-MOM (NCT07844161)
- Testing
- CODE-MOM
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Knowledge, Attitudes, Practice
Effectiveness of Metaverse-Based Immersive Technology Intervention for Oral Health Education: A Quasi-Experimental Study
To evaluate the effectiveness of pre- and post-intervention of oral health education using three interventions (conventional methods, mHealth, and the Metaverse platform) on the oral health status, knowledge, practices, and…
- Trial name
- NCT06543186
- Testing
- Oral health education lecture, Oral health education via mHealth on WhatsaApp, Oral health education via Metaverse platform on Meta-OHE
- Where
- 2 sites in Malaysia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universiti Teknologi Mara
Dietary Rice Bran Supplementation
Pilot Feasibility of Rice Bran Supplementation in Nicaraguan Children
The purpose is to assess feasibility of rice bran consumption in weaning children and collect pilot data on gut microbiome and metabolome modulation with rice bran intake for diarrheal prevention.
- Trial name
- NCT02615886
- Testing
- Observational Control, Rice bran
- Where
- 2 sites in United States, Nicaragua
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Marriage
Evaluation of a Brief Marriage Intervention for Internal Behavioral Health Consultants in Military Primary Care
The psychological health of military members is a critical element of force health protection and readiness. Frequent deployments and high operations tempo at home strain the relationships and families of today's military more…
- Trial name
- NCT02571478
- Testing
- Marriage Checkup
- Where
- 2 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Wright State University
Psychological Stress
Feasibility Pilot of Remote Mindfulness Training Across Multiple Sites (REFORM Pilot)
This is an operational feasibility pilot preceding the main REFORM multi-site randomized controlled trial. Approximately 60 adults across three sites will be randomized equally to one of four remotely delivered audio-guided…
- Trial name
- REFORM Pilot (NCT07888725)
- Testing
- Formal-Heavy Audio-Guided Mindfulness Training, Balanced Audio-Guided Mindfulness Training, Informal-Heavy Audio-Guided Mindfulness Training
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute for Human Development and Potential (IHDP), Singapore
Depression, Anxiety
A Letter Intervention in Primary Care Patients to Improve Depression and Anxiety Disorders
Currently patients thought to have anxiety or depression by their GPs are referred to the Primary Mental Health Team (PMHEIT) for psychiatric assessment.
- Trial name
- NCT00307697
- Testing
- receipt of copy of psychiatic assessment letter
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Chronic Musculoskeletal Pain
PainTrain-AI Pilot: Feasibility, Usability (SUS) and Concept-Shift in Primary Care and a Specialized Setting
This pilot will assess feasibility and usability (SUS) and explore concept shift (reduction of neurophysiology misconceptions) after exposure to a behavioral educational intervention (PainTrain AI), a digital clinical simulation…
- Trial name
- PT-AI Pilot (NCT07497997)
- Testing
- PainTrain-AI Behavioral Training
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Francesc Valenzuela Pascual
Healthy
Health4Life a Digital Intervention to Promote Healthy Lifestyle Behaviours From the Start of Life
The overall aim of this project is to evaluate the effectiveness and implementation of a digital intervention to support parents to create healthy lifestyle behaviours from the start of their infant's life, in order to prevent…
- Trial name
- Health4Life (NCT06798597)
- Testing
- Health4Life app
- Where
- Sweden
- Volunteers
- 504 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Loneliness
Developing and Testing a Machine Learning Enabled Mindfulness Intervention for Reducing Loneliness Among Hong Kong Chinese Older Adults
Develop and test an effective machine learning enabled application-based (app-based) mindfulness intervention for reducing loneliness of Hong Kong Chinese older adults.
- Trial name
- NCT07308613
- Testing
- Mindfulness - Continue, Mindfulness - Enhance human coaching, Mindfulness - Booster
- Where
- Hong Kong
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Weight Loss
Cost Effectiveness of Nutrition Intervention in Long Term Care
Inadequate food and fluid intake is a common problem among nursing home (NH) residents and one that can lead to under-nutrition, dehydration, weight loss, hospitalization, and even death.
- Trial name
- NCT02567526
- Testing
- Between-Meal Intervention Group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Depression, Depression in Children
Evaluation of a Training Course for Educational Professionals
The aim of this study is to evaluate the efficacy of a two-hour online training course on depression and mental health in childhood and adolescence in educational professionals to improve depression and mental health literacy.
- Conditions
- Depression, Depression in Children, Depression in Adolescence
- Trial name
- NCT06387108
- Testing
- training course
- Where
- Germany
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ludwig-Maximilians - University of Munich
Sleep, Foster Care
A Sleep Intervention for Preschoolers in Foster Care
Healthy sleep is critical for optimal health and development, but there are no public health interventions to support sleep for children in foster care.
- Trial name
- NCT06549491
- Testing
- Nurturing Sleep
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Physical Activity, Sedentary Behavior
FeetEnergy Approach to Increase Physical Activity and Reduce Screen Time in Adolescents
The purpose of this study is to find out whether an Internet-supported FeetEnergy approach and two home works integrated in three health education lessons can increase adolescents' active commuting to school and leisure-time…
- Conditions
- Physical Activity, Sedentary Behavior, Active Commuting, Psychosocial Factors
- Trial name
- FeetEnergy (NCT01633918)
- Testing
- Internet-supported FeetEnergy approach, Usual health education
- Where
- 2 sites in Finland
- Volunteers
- 1,291 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Behavioral Inhibition, Anxiety
A Multi-Method Early Intervention Program for Inhibited and Anxious Preschoolers
This project aims to develop and evaluate a novel early intervention program that targets the specific risk factors implicated in the development and persistence of shyness, social reticence, and withdrawal in children.
- Trial name
- NCT03486860
- Testing
- Parent Psychoeducation, Turtle Program
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Latarjet, Shoulder Injuries
Ability of Rotator Cuff Muscle Strength Levels, Assessed by Isokinetic Dynamometry, to Predict Return to Sport After Shoulder Stabilization Surgery by Open Latarjet Procedure
The stabilization surgical treatment by open Latarjet procedure is one of the reference treatments after anterior glenohumeral dislocation in athletes.
- Conditions
- Latarjet, Shoulder Injuries, Rotator Cuff Injuries
- Trial name
- ISO-LAT (NCT06602713)
- Testing
- Questionnaires, Exercices
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
HIV, Alcohol Use
Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings
Alcohol use is increasingly recognized as a key factor in morbidity and mortality among HIV-positive individuals and represents an important public health concern, given its associations with medication non-adherence, increases…
- Conditions
- HIV, Alcohol Use, Medication Adherence
- Trial name
- PLUS (NCT02390908)
- Testing
- Immediate PLUS intervention, Wait-list PLUS intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
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