Clinical trials: Interventional
Self-harm, Suicidal Ideation
CaMaPi for Adolescents/Young People With a History of Self-harm and Suicidal Ideation in Jos, Nigeria
Suicide and self-harm are global disease burden that contributes significantly to years of lost life and mortality.
- Trial name
- CaMaPi (NCT06440031)
- Testing
- CaMaPi, TAU
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Bleeding, Blood Loss, Surgical
PCC vs. FFP for Post Cardiopulmonary Bypass Coagulopathy and Bleeding
This will be the first prospective randomized controlled clinical trial directly comparing Prothrombin Complex Concentrate (PCC) Compared to Fresh Frozen Plasma (FFP) for post cardiopulmonary bypass microvascular bleeding and…
- Conditions
- Bleeding, Blood Loss, Surgical, Cardiovascular Surgical Procedures, Prothrombin Complex Concentrates
- Trial name
- NCT02557672
- Testing
- Prothrombin complex concentrate (Human), Fresh frozen plasma (FFP)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity
MOWI Qualitative Assessment
This qualitative study seeks to assess whether mobile health technologies are helpful for older adults. It is the first in a series of four studies whose overarching goal is to conduct a program of pilot research aimed at…
- Trial name
- NCT03041831
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
General Population
Efficacy of Different Versions of the Best Possible Self Intervention
The aim of this study is to analyze the efficacy of several variations of an already validated Positive Psychology Intervention (PPI) called Best Possible Self, using Information and Communication Technologies (ICT) in general…
- Trial name
- NCT03024853
- Testing
- BPS PAST, BPS PRESENT, BPS FUTURE
- Where
- Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Intubation, Endotracheal Tube Cuff Pressure
Effect of a Brief Educational Intervention on Endotracheal Tube Cuff Pressure
Endotracheal tube cuff pressure outside the recommended range of 20-30 cmH₂O is common in routine anesthesia practice. Over-inflation can injure the tracheal mucosa, while under-inflation increases the risk of aspiration and…
- Conditions
- Intubation, Endotracheal Tube Cuff Pressure, Anesthesia, Anesthesia,General
- Trial name
- NCT07891195
- Testing
- Brief educational intervention (educational video and reminder posters)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Cold Exposure
Simulation Study on Advanced Medical Procedures Under Extreme Environments
Background: In emergency situations in mountainous regions, medical professionals are often required to perform advanced medical procedures swiftly and efficiently.
- Trial name
- SIMEX-MED (NCT06640595)
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Palliative Care, Family
Dignity Talk: Helping Palliative Care Patients and Families Have Important Conversations
Dying patients and their families face many challenges near the end-of-life. Not only do patients often experience physical distress, but they also have feelings of loss of dignity, isolation, and uncertainty.
- Conditions
- Palliative Care, Family, End of Life Care
- Trial name
- DTalk (NCT01883375)
- Testing
- Dignity Talk, The Dignity Talk Communication Topics
- Where
- 13 sites in Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Distress, Psychological, Negative Affect
Nature Exposure Through Virtual Reality (NET-VR) in Older Adults
Daily exposure to nature is associated with improved mood and reduced anxiety symptoms in the overall population. Even brief contact with natural environments can lower stress and restore productivity.However, access to natural…
- Conditions
- Distress, Psychological, Negative Affect, Cognitive Functioning, Older Adults
- Trial name
- NET-VR (NCT07443657)
- Testing
- Nature-Based Virtual Reality Intervention, Waiting list
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Depression
An Intervention to Correct Dualistic Reasoning About the Effectiveness of Psychotherapy for Biologically Caused Mental Disorders
The goal of this clinical trial is to test in three samples, including sample 1: lay people without reported depression symptoms, sample 2: lay people with reported depression symptoms and sample 3: mental health clinicians.
- Trial name
- NCT05800119
- Testing
- Brain-level condition, Mind-level condition
- Where
- United States
- Volunteers
- 1,243 people, healthy volunteers welcome
- Sponsor
- Yale University
Language Development, Language, Child
Duet 2.0 Starting the Conversation: A New Intervention Model to Stimulate Language Growth in Underserved Populations
Caregiver-child language interactions in the first three years of life predict early language development, school readiness, and academic achievement.
- Conditions
- Language Development, Language, Child, Early Intervention
- Trial name
- NCT04692519
- Testing
- Duet Language Intervention Modules
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Temple University
Postural Balance
Neuromuscular Warm-up Intervention to Improve Postural Control in Female Handball Players
Female handball athletes are at a particular risk of sustaining lower extremity injuries. The study examines time-dependent adaptations of static and dynamic balance as potential injury risk factors to a specific warm-up program…
- Trial name
- NCT02925377
- Testing
- Neuromuscular warm-up, Standard warm-up
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg
Child Malnutrition, Feeding Behavior
Nutrition Intervention Integrated With Food Voucher to Improve Child Growth and Feeding Practices
Brief Summary: Background: The period from birth to two years of age is the "critical window" for the promotion of optimal growth, health, and development.
- Conditions
- Child Malnutrition, Feeding Behavior, Growth; Stunting, Nutritional
- Trial name
- NCT03641001
- Testing
- Child feeding counselling, food voucher, micronutrient powder, WASH
- Where
- Bangladesh
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Exercise, Women
Conmigo: A Mother-daughter Intervention to Promote Physical Activity
Regular physical activity (PA) contributes to reduced risk of obesity, chronic disease, cardiovascular disease, and cancer, and can improve emotional and mental health, learning, productivity, and social skills.
- Conditions
- Exercise, Women, Hispanic Americans, Child
- Trial name
- Conmigo (NCT04736030)
- Testing
- Intervention
- Where
- United States
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Rumination, Worry
Evaluating the Effects of a Self-help Mobile Phone Application on Worry and Overthinking in Young Adults Aged Between 16 and 24.
This project seeks to understand if a new self-help mobile phone application (called MyMoodCoach) is effective at reducing worry and overthinking, prominent risk factors that predict reduced well-being and poor mental health.
- Conditions
- Rumination, Worry, Repetitive Negative Thinking
- Trial name
- NCT04950257
- Testing
- digital CBT self-help including specific intervention elements to target worry and rumination.
- Where
- United Kingdom
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Down Syndrome, Healthy Aging
Group-based Resistance Training for Adults With Down Syndrome
The investigators are interested in Resistance Training as a physical exercise intervention for adults with Down syndrome. Resistance Training (or RT for short) is a popular form of physical exercise, which focuses on improving…
- Conditions
- Down Syndrome, Healthy Aging, Resistance Training
- Trial name
- NCT07347912
- Testing
- Resistance Training, Services as Usual Control Group
- Where
- Ireland
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Saint John of God Intellectual Disability Services - Dublin South East
Overweight and Obesity, Cardiovascular Diseases
Study Consortium for Evaluation of RNPC Program in Obese and Overweight Patients (SCOOP-RNPC)
The investigators hypothesize that weight loss obtained with the French RNPC weight reduction program is beneficial for the general health of overweight/obese patients in the medium term.
- Conditions
- Overweight and Obesity, Cardiovascular Diseases, Metabolic Disease, Diabete Type 2
- Trial name
- SCOOP-RNPC (NCT05857319)
- Testing
- Nutritional Psycho-Behavioral Reeducation Program
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Groupe Éthique et Santé
Self-Control, Caregiver Burden
Learned Resourcefulness Intervention
This study aimed to test the effects of a learned resourcefulness interveniton program on the learned resourcefulness, caregiver burden, quality of life for older family caregivers.
- Conditions
- Self-Control, Caregiver Burden, Quality of Life
- Trial name
- NCT03717077
- Testing
- learned resourcefulness intervention
- Where
- Taiwan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Edentulous Maxilla
Clinical Study Investigating the Efficiency and Complications Related to Two Different Procedures Used for the Preparation of Dentures Applied in Patients With Edentulous
The principal aim of the study is to evaluate the prosthetic complications with CAD-CAM fabricated provisional prostheses and denture conversion prostheses after 3 months of function.
- Trial name
- NCT05332977
- Testing
- CAD-CAM fabricated provisional prosthesis, DC (denture conversion) provisional prosthesis
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Healthy Controls, Parkinson's Disease
Development of Digital Services for Parkinson's Disease
In this project, ocular motor, pupil and gait data in people with Parkinson's disease (PD) will be collected in order to develop machine learning models for the diagnosis and monitoring of PD.
- Trial name
- NCT06733077
- Testing
- gait with cueing wearable device and neuro-ocular performance
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Athlete Foot
Neurodynamics to Improve Jump Functionality in Trampoline Jump Gymnasts
The goal of neurodynamics is to restore homeostasis of peripheral nerves. In the current context there is varied evidence that links neurodynamics with clinical pain treatments or different pathologies, but little evidence…
- Trial name
- NCT04289857
- Testing
- Neurodynamic training
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
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