Clinical trials: Interventional
Respiratory Infections in Children
Infant Formula and Toddler Drink Feeding Intervention
The purpose of this randomized, multi-center, controlled, double-blind, parallel study is to evaluate the health and developmental outcomes of children fed a new infant formula and toddler drink through 24 months of age.
- Trial name
- NCT04495738
- Testing
- Control Infant Formula, Control Toddler Drink, Experimental Infant Formula
- Where
- 27 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Abbott Nutrition
Cystic Fibrosis, Chronic Obstructive Pulmonary Disease (COPD)
Prevalence and Treatment of Urinary Incontinence in Women With Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Women with chronic lung disease characterised by chronic cough report urinary incontinence. Recently there have been reports of increased urinary incontinence in girls and women with cystic fibrosis.
- Trial name
- NCT00164138
- Testing
- Pelvic floor training group
- Where
- 2 sites in Australia
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Bayside Health
Healthy Aging
Virtual Reality Study - COVID-19 Protocol
The overarching goal of this pilot clinical trial is to use a novel virtual reality (VR)-based intervention that simultaneously engages physical and cognitive activity aimed at improving brain and cognitive outcomes in older…
- Trial name
- NRVR (NCT04678778)
- Testing
- Physical and Cognitive Activity
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Healthy
Improving Survey Procedures for Young Men Who Have Sex With Men in Web-based HIV Prevention: Retention Study
The purpose of this study is to test the efficacy of alternative methods to improve survey completion.
- Trial name
- NCT02424643
- Testing
- Monetary Incentive, Altruistic Incentive, Dashboard Incentive
- Where
- United States
- Volunteers
- 1,131 people, healthy volunteers welcome
- Sponsor
- Emory University
PreDiabetes
Examining the Impact of a Self-compassion Intervention on Physical Activity Behaviour Among People With Prediabetes
The investigators plan to examine whether teaching people at risk for type two diabetes to use self-compassion (orientation to care for oneself during difficult situations) helps them self-manage and increase their physical…
- Trial name
- NCT04863235
- Testing
- Control Group, Intervention Group
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Intervention Studies, ASA Physical Status I
Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3.
- Conditions
- Intervention Studies, ASA Physical Status I, Intracanal Medication, Periapical Abscess
- Trial name
- RCT (NCT07641933)
- Testing
- Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alzheimer Disease, Glucose Metabolism
Feasibility Study of a Community Pilot Project for the Prevention of Alzheimer's Disease: the KetoHome Study.
The purpose of this study is to assess whether it is possible to carry out a research project with a nutritional intervention in senior's residence.
- Trial name
- KetoHome (NCT05642052)
- Testing
- low carb diet, Regular diet
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy Adults
A Study to Learn About How the Study Medicines Called Itraconazole and Probenecid Change How the Body Processes PF-07220060
The purpose of the study is to see and learn the effect of multiple doses of a strong CYP3A4 inhibitor and a potent UGT2B7 inhibitor on the PK of PF-07220060.
- Trial name
- NCT07160738
- Testing
- PF-07220060, Itraconazole, Probenecid
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pfizer
Substance Use
Drug Abuse Prevention Among Girls Through a Mother-Daughter Intervention
The purpose of this study is to determine a computer- and family-based drug abuse prevention program is able to reduce drug use among early adolescent girls.
- Trial name
- NCT01236248
- Testing
- Prevention
- Where
- United States
- Volunteers
- 916 people, healthy volunteers welcome
- Sponsor
- Columbia University
Body Image, Physical Activity
SDT-Based Intervention for Exercise Motivation in Female Students
Physical inactivity, maladaptive exercise motives, and body image concerns are highly prevalent among young adult women and are associated with reduced psychological well-being and increased risk for disordered eating.
- Trial name
- No acronym use (NCT07506343)
- Testing
- Experimental group will receive a face-to-face psychoeducational program grounded in Self-Determination Theory. Control group will no receive any psychoeducational program
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Neurocognitive Disorders, Postoperative Delirium
Creatine and Perioperative Brain Health
The overall goal of this study is to explore the effects of perioperative oral creatine supplementation on cognitive function and physiological responses to surgery in older adults.
- Conditions
- Neurocognitive Disorders, Postoperative Delirium, Postoperative Outcomes
- Trial name
- CREATE (NCT07310043)
- Testing
- Creatine monohydrate
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Endoscopic Surgical Procedure
Percutaneous Sigmoid Fixation For Management Of Recurrent Sigmoid Volvulus
The investigators included all patients who were presented to emergency department with recurrent sigmoid volvulus at Zagazig University hospital between (August 2024 to August 2025).
- Trial name
- NCT07155304
- Testing
- percutaneous sigmoid colon fixation
- Where
- Egypt
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Sarcopenia, Frailty
Implementation of ProMuscle in Daily Practice
Implementation of a previously shown (cost-)effective combined lifestyle intervention for community living older adults, ProMuscle, in at least four of the eight communities of the 'Foodvalley' in the Netherlands.
- Conditions
- Sarcopenia, Frailty, Aging Problems
- Trial name
- PUMP-fit (NCT05672004)
- Testing
- PUMP-fit strategy (implementation toolbox), Implementation as usual
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Brain Aging
Blueberry Intervention Study for Brain Aging
The purpose of this study is to determine if increased blueberry intake helps increase brain antioxidant (glutathione) and cerebral blood flow in older adults.
- Trial name
- NCT05024916
- Testing
- Intervention, Control
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Diagnoses Disease
Whack-a-Mole: Testing an Intervention to Increase Melanoma Identification
The purpose of this study is to evaluate an interactive game designed to increase people's ability to identify cancerous moles.
- Trial name
- NCT04069104
- Testing
- ABCD Information, UDS information, Standard (clinical) feedback
- Where
- United States
- Volunteers
- 1,849 people, healthy volunteers welcome
- Sponsor
- University of Miami
Hypothermia, Morbidity
Perinatal Hypothermia, Risk Factors and Long-Term Consequences in Guinea-Bissau, Westafrica
Low body temperature (hypothermia (HT)) at birth contributes to infant mortality in low-income countries. A study from Guinéa-Bissau indicates that HT results in an increased mortality rate, which persist at least two months…
- Conditions
- Hypothermia, Morbidity, Mortality
- Trial name
- NCT00429000
- Testing
- thermospot
- Where
- Guinea-Bissau
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Dental Impression Techniques
Intraoral Scanning Versus Alginate Impressions in Dental Students
Dental impressions are used to create a record of a person's teeth and oral structures. Conventional impressions are made using impression material placed in a tray, whereas digital impressions are obtained using an intraoral…
- Trial name
- NCT07705009
- Testing
- Conventional Alginate Impression, TRIOS 3 Intraoral Scanner, Medit i700 Intraoral Scanner
- Where
- Vietnam
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Long-Term Memory Decline, Mild Cognitive Impairment
Wayfinding Intervention in High-Fidelity Long-Term Memory
Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment.
- Trial name
- LABYR (NCT04253587)
- Testing
- LabyrinthVR, Coherence, Tablet
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Vaginal Flora Imbalance, ASC-US
"Lactobacillus Crispatus M247, LSIL and Microbiota"
Patients affected by ASC-US/ low-grade HPV cervical lesions will be randomly assigned to treatment arm vs control arm. The treatment arm will include the characterization of the vaginal microbiota at enrollment (T0), 4 months of…
- Conditions
- Vaginal Flora Imbalance, ASC-US, LSIL, HPV Infection
- Trial name
- NCT05808816
- Testing
- Lactobacillus Crispatus M247
- Where
- Italy
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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