Clinical trials: Interventions
Vaginal Flora Imbalance
FB101 Intervention in Women Screened to Have Vaginal Dysbiosis
This study will explore and map the potential shifts in vaginal microbiomes as a consequence of a microbial intervention with product FB101 in healthy, asymptomatic volunteer women screened to have vaginal dysbiosis based on…
- Trial name
- DYSCOVER-1 (NCT05114031)
- Testing
- FB101
- Where
- Ireland
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Freya Biosciences ApS
Anxiety, Depression
Digital Single Session Intervention for Youth Mental Health
The aim of this study is to test the effectiveness of a single-session, digital intervention teaching the principle of practicing the opposite, when administered to youths on the waitlist for psychotherapy, with usual waitlist…
- Conditions
- Anxiety, Depression, Conduct Disorder, Stress
- Trial name
- NCT05449002
- Testing
- Practicing the Opposite (PTO), Usual Clinical Care
- Where
- 5 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Harvard University
Postpartum Depression, Anxiety
Mothers and Babies Qatar (MB-Q): A Postpartum Depression Intervention
Qatar Mothers and Babies is a 4-year collaboration between Northwestern University Feinberg School of Medicine and Sidra Medicine in Doha, Qatar that will generate and evaluate a cultural and contextual adaptation of the Mothers…
- Conditions
- Postpartum Depression, Anxiety, Diabetes
- Trial name
- MB (NCT04442529)
- Testing
- Mothers and Babies (MB)
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sidra Medicine
Mitigation of Acute Voice Changes Follwing Rigorous Voice Use
Effect of Fish Oil Supplementation on the Voice of Female Professional Voice Users (PVU)
The design of the study allows us to test if there are differences in a battery of voice assessments (Aim 1) and biomarkers from vocal fold secretions (Aim 2) over time (within-subjects factor with 6 levels: 3 pre-intervention…
- Trial name
- PVU (NCT07800702)
- Testing
- Omega-3 Polyunsaturated Fatty Acids
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Baylor University
Functional Dyspepsia, Irritable Bowel Syndrome
The Efficacy and Safety of "BST104" (Lonicera Flos Extract) in Mild to Moderate Functional Dyspepsia Subjects
This study was conducted to prove the efficacy of BST-104 in patients with mild to moderate FD.
- Trial name
- NCT04008901
- Testing
- BST-104 (Lonicera Flos Extract)
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Exercise, Anthocyanins
Effects of an Elderberry-Based Functional Beverage on Exercise Performance, Muscle Structure, and the Gut-Muscle Axis
Introduction: Increasing sedentary lifestyle, microbiota imbalance and exercise-induced muscle fatigue are among the main causes of metabolic stress and performance decline, even in young individuals.
- Conditions
- Exercise, Anthocyanins, Muscle Size
- Trial name
- NCT07054671
- Testing
- Elderberry-Based Functional Beverage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Burdur Mehmet Akif Ersoy University
Resilience, Psychological, Mental Well-being
Evaluating a Digital Intervention to Improve Resilience and Reduce Stress in Stanford Populations
High-achieving academic and entrepreneurial populations face elevated risks of chronic stress, anxiety, and burnout. These populations often underutilize mental health services due to stigma, time constraints, or accessibility…
- Trial name
- SIER-WONE (NCT07565571)
- Testing
- Intervention WONE App (full Version)
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Stanford University
Autism Spectrum Disorder
Feasibility Controlled Trial of an 8-session Group Intervention for Siblings of Children Who Have ASD
A feasibility controlled trial of an eight-session group intervention for siblings of children who have an Autism Spectrum Disorder (ASD). Children will be recruited from a multi-academy trust of nine schools.
- Trial name
- NCT04714606
- Testing
- Sibling support group, None - control condition
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Mindfulness, Alzheimer's Disease Related Dementia
Mindfulness to Enhance Cognitive Health in Latino Older Adults
The primary objective of the proposed research is to investigate the promise and underlying mechanisms of mindfulness training as a preventative lifestyle intervention to enhance cognitive health in Latino older adults, thereby…
- Trial name
- MLX (NCT07040904)
- Testing
- mindfulness
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Other Conditions That May Be A Focus of Clinical Attention
Effectiveness of Buddhist Intergrated Group Intervention on Minefulness in Adolescents
The pupose of the study is to determine the effectiveness of the Buddhist integrated group intervention improve the mindfulness in adolescents by a randomized controlled trial.The study divede the adolescents in two groups group…
- Trial name
- NCT01605604
- Testing
- buddhist mind fullness
- Where
- Thailand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Dehydration, Older Adults (65 Years and Older)
Effect of a Mobile-Based Hydration Tracking Program on Knowledge, Attitudes, and Behaviors in Older Adults
This randomized controlled trial aims to evaluate the impact of a mobile-friendly, web-based hydration tracking application (named "SIVI") on hydration-related knowledge, attitudes, and behaviors in older adults.
- Conditions
- Dehydration, Older Adults (65 Years and Older), Hydration Status, Self-management Behavior
- Trial name
- SIVI (NCT07043933)
- Testing
- Mobile-Compatible Web-Based Hydration Tracking Program
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ezgi Atasoy
Metabolic Disease
Effectiveness of Technology for Metabolic Diseases Combined Sarcopenia
The lifestyle program intervention program focusing on healthy dietary habit and exercise effectively prevents metabolic syndrome, sarcopenia or frailty.
- Trial name
- NCT05476536
- Testing
- self-management skills and healthy technology APP
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Chang Gung University of Science and Technology
Breast Cancer Female
High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women
The purpose of this second pilot study is to extend the feasibility demonstrated in NCT02963740 that the intervention achieves high levels of moderate to vigorous physical activity (MVI PA) and modulates risk biomarkers for…
- Trial name
- NCT03270111
- Testing
- Supervised Exercise, Home-based Exercise, Reduced Energy Diet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Weight Loss
Effects of a Minimal-Contact Lifestyle Intervention on Physical Activity, Diet, and Body Weight
The purpose of this study is to conduct a pilot randomized controlled trial, to determine whether providing financial incentives for meeting daily step goals (a) increases the daily step counts of participants, (b) increases…
- Trial name
- STEP (NCT02008071)
- Testing
- Daily step goal financial incentive, Standard of Care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Pediatric Obesity, Pediatric Nutrition
Storybook-Based Nutrition Education for Preschoolers
This project aims to design a nutrition-based educational storybook for preschool children and to evaluate its effect on improving general nutrition behaviors and reducing possible picky eating habits.
- Conditions
- Pediatric Obesity, Pediatric Nutrition, Nutrition Education, Nutrition Education Program
- Trial name
- NCT07540234
- Testing
- Behavioral Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Pregnancy, Postpartum Period
Effect of Exercise on Perinatal Depression
Fifteen percent of women experience depression during pregnancy or postpartum (i.e., perinatal depression). Furthermore, 38% of low income women experience postpartum depression.
- Conditions
- Pregnancy, Postpartum Period, Depression
- Trial name
- NCT02791932
- Testing
- Exercise
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
AKI - Acute Kidney Injury
Allopurinol and Trimetazidine as a Preventive of Acute Kidney Injury in PCI Patients
Contrast-associated acute kidney injury (CA-AKI) is a common complication of procedures with intravascular contrast. Generally, CA-AKI is defined as serum creatinine (Scr) ≥ 25 to 50% or Scr rise around 0.3 to 0.5 mg/dl.
- Trial name
- NCT05540184
- Testing
- Trimetazidine 35 mg, Allopurinol 300 MG, Normal saline
- Where
- Egypt
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Stress, Anxiety
A Brief Online Mindfulness Intervention: An RCT Protocol
University students often experience emotional distress that originates from inside or outside academia, and for which treatment would be welcome.
- Conditions
- Stress, Anxiety, Depression
- Trial name
- NCT05882565
- Testing
- A brief (14-day) online mindfulness intervention, Psychoeducation online
- Where
- Indonesia
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Ka Yan
Obesity
Influence of a Lifestyle Intervention in Preschool Children on Physiological and Psychological Parameters
Childhood obesity and low fitness tracks into adulthood and carries significant co-morbidities. The investigators test the hypothesis that a multidisciplinary multilevel lifestyle intervention in preschool children in the French…
- Trial name
- Ballabeina (NCT00674544)
- Testing
- Lifestyle intervention
- Where
- Switzerland
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Pulmonary Disease, Chronic Obstructive, Asthma COPD
Impact of a Mobile Phone and Educational Intervention
The purpose of this pilot study was to: 1. partner with African American churches to increase awareness of COPD. 2. use a community-based approach to facilitate early detection of COPD in the church setting.
- Trial name
- NCT06878898
- Testing
- Education and mobile phone text-messaging, Education only
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Kent State University
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