Clinical trials: Interventions
Psychosis; Schizophrenia-Like, Healthy Controls
Mechanisms of Response to Therapeutic Intervention in Clinical High Risk (CHR) for Psychosis
This study, "Psychobiological Follow-up Study of Transition from Prodrome to Early Psychosis", will be conducted in collaboration with the Shanghai Mental Health Center (SMHC) and several data processing sites in the United…
- Trial name
- NCT06542640
- Testing
- Mb-rt-fMRI-NFB, rTMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Trauma, Brain
Caregiver Wellness After Traumatic Brain Injury (CG-WELL): An Intervention Designed to Promote Well-being in Caregivers of Acute Moderate to Severe Traumatic Brain Injuries
After injury, survivors of msTBI depend on informal family caregivers. Upwards of 77% of family caregivers experience poor outcomes, such as adverse life changes, poor health related quality of life, and increased depressive…
- Trial name
- CG-Well (NCT05307640)
- Testing
- CG-Well, Information Support & Referral (ISR)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Natalie Kreitzer
Pediatric Intensive Care Unit, Comfort
Comfort Intervention in PICU Children
This randomized controlled trial evaluates a family-centered comfort intervention for children hospitalized in a pediatric intensive care unit.
- Conditions
- Pediatric Intensive Care Unit, Comfort, Anxiety in Children, Fear
- Trial name
- CCI-PICU (NCT07441668)
- Testing
- Intervention Family-Centered Comfort, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Blood Pressure
The DREAM Study: A Multidimensional Sleep Health Intervention for Improving Cardiometabolic Health
The purpose of this randomized clinical trial is to evaluate the impact of a multidimensional sleep health promotion intervention on blood pressure, glycemic control indicators, anthropometric markers of adiposity, and lifestyle…
- Trial name
- NCT06285968
- Testing
- Multidimensional Sleep Health Promotion Intervention
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
HIV/AIDS
MyPEEPS Mobile Plus: A Multi-Level HIV Prevention Intervention for Young MSM
MyPEEPS Mobile Plus, a multi-level intervention for improving HIV prevention outcomes in YMSM, is a novel and evidence-driven approach using mobile technology to deliver HIV prevention information specifically developed for YMSM.
- Trial name
- NCT06741618
- Testing
- MyPEEPS Mobile, Electronic PrEP peer navigation
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Columbia University
Language Impairment, Down Syndrome
Phenotypic Specific Communication Intervention for Children With Down Syndrome
Children with Down syndrome (DS) have greater difficulty acquiring expressive language than is predicted by their general cognitive abilities and language comprehension (Miller, 1999).
- Trial name
- Merck (NCT02158390)
- Testing
- Jasper-EMT with words and AAC
- Where
- 2 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Early Onset Alzheimer Disease, Frontotemporal Dementia
RHAPSODY-plus: Online Counseling for Family Caregivers of Patients With Young Onset Dementia
The RHAPSODY-plus project consists of two parts. In a first step carers of people with young onset dementia (YOD; onset before the age of 65) have the opportunity to use the RHAPSODY online program (Kurz et al., 2016) to inform…
- Trial name
- RHAPSODY-plus (NCT03923517)
- Testing
- RHAPSODY online program and MEET online sessions
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Mental Health Disorder, Substance Use
Stigma Intervention Among Primary Health Workers in Toronto
This project is measuring the effectiveness of an anti-stigma intervention among primary care providers. Both staff and clients will be asked to complete survey data in order to measure the effectiveness.
- Trial name
- NCT03043417
- Testing
- CHC's given the intervention
- Where
- Canada
- Volunteers
- 485 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Oral Cancer, Palliative Supportive Care
Early Palliative Care For Patients With Oral Cancer in Sri Lanka
The goal of this quasi experimental study is to develop and assess the effectiveness of an early palliative care intervention in patients with oral cancer in Sri Lanka.
- Conditions
- Oral Cancer, Palliative Supportive Care, Psychological Distress, Quality of Life of Patients
- Trial name
- NCT06726317
- Testing
- Early palliative care integration
- Where
- 4 sites in Sri Lanka
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Colombo
Advance Care Planning
Culturally Tailoring an Advance Care Planning Intervention for American Indians
This project has three specific aims: (1) culturally tailor the content of the Make Your Wishes about You (MY WAY) ACP curriculum and guide for one American Indian tribe; (2) assess the feasibility of the culturally-tailored MY…
- Trial name
- NCT05304117
- Testing
- Advance Care Planning
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Western Carolina University
Attention Deficit Disorder With Hyperactivity
Reducing Attention Deficit Hyperactivity Disorder in Kindergarten and Pre-Kindergarten Children
This study will determine the effectiveness of an intervention for preventing at-risk kindergarten and pre-kindergarten children from developing attention deficit hyperactivity disorder.
- Trial name
- NCT00895908
- Testing
- Friendship Group, Academic tutoring
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Penn State University
Developmental Coordination Disorder
Motor Intervention for Children With Developmental Coordination Disorder
This study focuses on the effects of physical activity in schools on the cognitive function and physical fitness of children with and without developmental coordination disorder (DCD).
- Trial name
- NCT06544317
- Testing
- physical training
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhiguang Ji
Melanoma
Tailored Intervention for Melanoma Patient's Families
The purpose of the investigators' study is to find the best way to provide information about sun protection and skin cancer detection.
- Trial name
- NCT00816374
- Testing
- Reading materials and discussions, Questionnaires
- Where
- 3 sites in United States
- Volunteers
- 553 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
Sleep Disorder, Insomnia
Brain Gym Therapy on Quality of Sleep Among Elderly People
This clinical trial aims to evaluate the impact of Brain Gym Therapy on the quality of sleep among elderly individuals attending healthcare facilities.
- Conditions
- Sleep Disorder, Insomnia, Cognitive Function Abnormal, Old Age; Debility
- Trial name
- BG/E (NCT06553690)
- Testing
- Brain Gym Therapy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Child Development, Activity, Motor
Early Movers Pilot Intervention
Our Early Movers longitudinal study found that adherence to the Canadian 24-Hour Movement Guidelines in infancy is low across demographic groups, impacting overall development.
- Trial name
- NCT06538090
- Testing
- Early Movers
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Happiness
Psychosocial Benefits of Gratitude Journals
This randomized controlled study will examine the effects of different interpersonal gratitude journals compared to a neutral control journal on psycho social outcomes.
- Trial name
- NCT02570685
- Testing
- Reflective Interpersonal Gratitude, Reflective-Behavioral Gratitude, Neutral Control Journal
- Where
- Ireland
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Health Promotion, Health Education
The Future of Viral Communications: Video-Based Health Promotion Strategies for COVID-19 Vaccinations
The investigators aim to study whether education, in the form of three two-minute educational videos about COVID-19 vaccine development and dissemination, reduces vaccine hesitancy and increases intent to vaccinate.
- Conditions
- Health Promotion, Health Education, COVID-19 Vaccines
- Trial name
- NCT04876885
- Testing
- Educational video
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- McMaster University
Vaccination Uptake, Knowledge
Enhancing Maternal Vaccine Knowledge and Uptake: The InTroDuce-Programme Trial
The goal of this InTroDuce-Programme interventional trial aims to test whether a web-based educational program can improve pregnant women's knowledge about Influenza and Tdap vaccinations and increase their intention to get…
- Conditions
- Vaccination Uptake, Knowledge, Tetanus, Diphtheria and Acellular Pertussis Vaccination, Influenza
- Trial name
- NCT06815250
- Testing
- Influenza and Tdap Vaccination Educational and Learning Module
- Where
- 4 sites in Malaysia
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Metabolic Response to Dietary Modification
The CLOCK Study - A Human Dietary Intervention Study on Peripheral Circadian Clocks and Energy Metabolism
This human dietary intervention study with a cross-over design aims to investigate the effect of two different diurnal patterns of meal composition on peripheral circadian clocks and energy metabolism in healthy men.
- Trial name
- CLOCK (NCT02487576)
- Testing
- Carbohydrate-rich (HC), Fat-rich (HF)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- German Institute of Human Nutrition
Guardian, Hematologic and Lymphocytic Disorder
Parenting Skills Intervention in Improving Medication Adherence in Pediatric Cancer Patients
This trial studies how well a parenting skills intervention works in improving medication adherence in pediatric cancer patients.
- Conditions
- Guardian, Hematologic and Lymphocytic Disorder, Malignant Neoplasm, Parent
- Trial name
- NCT03895918
- Testing
- Educational Activity, Patient Monitoring, Questionnaire Administration
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
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