Clinical trials: Interventions
Right Hemispheric Stroke
Functional Connectivity and Predictors of Affective Aprosodia Intervention in Subacute Right Hemisphere Stroke
This study is an investigation of a behavioral speech and language treatment for emotional prosody recognition and production deficits in subacute right hemisphere stroke.
- Trial name
- NCT04575909
- Testing
- Aprosodia Intervention, No-Intervention
- Where
- United States
- Sponsor
- Johns Hopkins University
Menopause
Mindfulness-based Educational Intervention on Anxiety, Depression, Stress and Quality of Life on Menopausal Woman
Mindfulness-based educational intervention is a structured program that incorporates principles of mindfulness to help individuals develop greater awareness and acceptance of their thoughts, feelings, and bodily sensations.
- Trial name
- mindmenopaus (NCT06421909)
- Testing
- mindfulness-based educational intervention
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Dyssomnias
A Multicomponent Intervention for Prevention and Treatment of Sleep Disturbances in a Psychiatric Intensive Care Unit
Hospitalized adult patients suffer from sleep deprivation, which has been associated with multiple negative consequences, both in short and in the long term.
- Trial name
- SUEÑA-SM (NCT04995263)
- Testing
- Sueña component 1: Sleep Hygiene Promotion, Sueña component 2: Periodic Anxiety and Pain Screening, Sueña component 3: Hypnotics and Caffeine Regulation
- Where
- Chile
- Volunteers
- 120 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Breast Cancer, Cardiotoxicity
The Effects of Two Exercise Interventions on Breast Cancer Patients Undergoing Cardiotoxic Chemotherapies
The purpose of this study is to determine if exercise preconditioning can mitigate the off target effects of chemotherapy treatment on measures of cardiovascular function, inflammatory responses, and quality of life.
- Conditions
- Breast Cancer, Cardiotoxicity, Cardiovascular Diseases
- Trial name
- NCT05786014
- Testing
- High Intensity Interval Exercise, Moderate Intensity Walking
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Depression, Anxiety
A Randomized Controlled Trial of a VR Social Music-Movement Exergame for Depression and Anxiety in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of a virtual reality (VR) music-movement exergaming intervention for improving social connectedness and psychological well-being among young adults.
- Trial name
- VR-MOVE (NCT07482852)
- Testing
- VR social musical exergame, VR solo musical exergame, Waitlist control
- Volunteers
- 130 people
- Sponsor
- Hunan University of Traditional Chinese Medicine
Acute Kidney Injury
PRevention of Acute Kidney Injury Initiated With Electronic Surveillance Enhancement
Introduction: Acute kidney injury (AKI) increases mortality, hospital cost, and rate of progression toward end stage kidney disease 1-4. Early diagnosis and management of AKI is known to improve the above mentioned outcomes.
- Trial name
- PRAISE (NCT01621152)
- Testing
- Conventional management arm, AKI sniffer instigated AKI management
- Where
- United States
- Volunteers
- 2,266 people
- Sponsor
- Mayo Clinic
Inactivity/Low Levels of Exercise, Inactivity, Physical
A Collaborative Theory-based Intervention to Promote Physical Activity Among Sedentary Parents and Their Children
Insufficient physical activity in children and adults is linked to increased risk of physical and mental health conditions. Parents have an important influence on their children's activity, and preliminary aimed at promoting…
- Trial name
- ProAct (NCT06070038)
- Testing
- Integrated Behaviour Change Based Intervention Materials
- Where
- Finland
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Mental Stress, Hypertension
Impact of a Health and Mental Health Promotion Intervention Among Jordanians and Syrians.
Given the heightened risk of NCDs and mental health issues, it is critical for Jordanians and Syrian refugees to have access to prevention based health services.
- Conditions
- Mental Stress, Hypertension, Diabetes
- Trial name
- NCT03721848
- Testing
- Healthy community clinic NCD+MH, Healthy community clinic NCD
- Where
- Jordan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
HIV Infections, Pregnancy Related
Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe
The purpose of this study is to develop a multi-level PrEP adherence and persistence intervention as an adaptation of the TENDAI ('grateful' in Shona) program, a problem-solving approach to reduce depression and increase HIV…
- Conditions
- HIV Infections, Pregnancy Related, Depression, Anxiety
- Trial name
- TENDAI4PrEP (NCT06226155)
- Testing
- TENDAI4PrEP, Enhanced treatment as usual
- Where
- Zimbabwe
- Volunteers
- 165 people
- Sponsor
- Massachusetts General Hospital
Coronary Artery Disease, Coronary Occlusion
Coronary CTO PCI Using Antegrade Wiring Strategy With a First-choice Gladius Guidewire (Gladius First)
The Gladius First trial is designed as a single-centre, open, prospective, randomized clinical trial aimed to assess the efficiency and safety of coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI)…
- Conditions
- Coronary Artery Disease, Coronary Occlusion, Percutaneous Coronary Intervention
- Trial name
- Gladius First (NCT04691778)
- Testing
- CTO PCI with the first-choice Gladius guidewire, CTO PCI without the first-choice Gladius guidewire
- Where
- Poland
- Volunteers
- 69 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Non-valvular Atrial Fibrillation, Stroke
Study of Safety and Efficacy of a Left Atrial Appendage Occulder
This study mainly evaluated the feasibility and safety of a kind of Left Atrial Appendage Occluders which is to prevent ischemic stroke caused by nonvalvular atrial fibrillation (AF)
- Trial name
- NCT02937025
- Testing
- The Left Atrial Appendage Occulder of Shanghai Push Medical Device Technology CO.td
- Volunteers
- 154 people
- Sponsor
- Ya-Wei Xu
Multiple Sclerosis
Unraveling Early Walking Dysfunction in Non-disabled MS People: Assessment and Potential Therapeutic Interventions
The aim of the study is to set up a pilot study to investigate the effects of treadmill training in preventing the onset and worsening of walking impairments, balance deficits and fatigue.
- Trial name
- NCT03492450
- Testing
- Treadmill training
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Infection, Antimicrobial Stewardship
Quality Improvement Intervention for a Safe Antimicrobial Use Reduction in Critically Ill Patients
The goal of this clinical trial is to learn if an educational intervention with audit and feedback on physicians and health care professionals who participate in antimicrobial treatment decisions can reduce the use of…
- Conditions
- Infection, Antimicrobial Stewardship, Critically Ill Intensive Care Unit Patients
- Trial name
- SAFE-REDUCE (NCT07093450)
- Testing
- Educational Quality Improvement Intervention
- Where
- 9 sites in Brazil
- Volunteers
- 9,000 people
- Sponsor
- Hospital Sirio-Libanes
Methicillin Resistant Staphylococcus Aureus
Detection, Education, Research and Decolonization Without Isolation in Long-term Care Facilities
Our hypothesis for the DERAIL MRSA program is that one can safely remove the colonization risk from nearly all residents (patients) in a way that does not interfere with the desired life-style for persons in these facilities and…
- Trial name
- DERAIL_MRSA (NCT01302210)
- Testing
- Decolonization
- Where
- United States
- Volunteers
- 22,302 people
- Sponsor
- Endeavor Health
Stroke
A Psychoeducational Intervention for Stroke Family Caregivers
This is a randomized controlled trial with a 3-month psychoeducational program as intervention, followed by a 3 month observational period.
- Trial name
- NCT02080910
- Testing
- Psychoeducation
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Chinese University of Hong Kong
Stable Angina, Unstable Angina
International Collaboration of Comprehensive Physiologic Assessment
The current study evaluated prognostic implication of comprehensive physiologic assessment using fractional flow reserve, coronary flow reserve (CFR) and index of microcirculatory resistance (IMR).
- Conditions
- Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction, ST-segment Elevation Myocardial Infarction
- Trial name
- NCT03690713
- Testing
- Fractional flow reserve, coronary flow reserve, and index of microcirculatory resistance
- Where
- 4 sites in Japan, South Korea and 1 more
- Volunteers
- 1,397 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Intravascular Ultrasound Guided Drug Eluting Stents Implantation in "All-comers" Coronary Lesions （ULTIMATE Trial）
A number of 1448 patients scheduled for elective percutaneous coronary intervention (PCI) with a native coronary stenosis suitable for DES implantation and IVUS imaging are openly randomized 1:1 to either IVUS guidance or…
- Trial name
- ULTIMATE (NCT02215915)
- Testing
- Angiography, IVUS, DES implantation
- Where
- China
- Volunteers
- 1,448 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Postoperative Delirium
Pilot and Feasibility Study of a Mirrors Intervention for Reducing Delirium in Older Cardiac Surgical Patients
This pilot cluster-randomised controlled trial aims to determine whether the use of bedside mirrors, as a clearly defined part of patients' postsurgical ICU care, can reduce delirium and improve outcomes in the older cardiac…
- Trial name
- NCT01599689
- Testing
- Mirrors Intervention
- Where
- United Kingdom
- Volunteers
- 223 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Coronary Arterial Disease (CAD), Distal Raidal Artery
Hand Dysfunction in Coronary Diagnosis and Intervention Via Distal Radial Access
Randomized controlled trial for comparison of the hand dysfunction in coronary diagnosis and intervention via distal vs conventional radial access
- Conditions
- Coronary Arterial Disease (CAD), Distal Raidal Artery, Hand Functions
- Trial name
- CONFINE (NCT06986889)
- Testing
- Conventional radial artery access, Distal radial artery access
- Volunteers
- 640 people
- Sponsor
- Wujin People's Hospital
Decision Making, Bipolar Disorder
Cognitive De-Biasing and the Assessment of Pediatric Bipolar Disorder
The primary aim is to test the efficacy of a new intervention to improve clinical judgment. The investigators focus on the assessment of pediatric bipolar disorder (PBD), a controversial diagnosis with frequent diagnostic errors…
- Trial name
- NCT01799291
- Testing
- Decision Making Tutorial
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
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