Clinical trials: Interventions
Allergy
The Prolonged Effect of Consumption of a Partially Hydrolyzed Infant Formula During the First 6 Months of Life on the Development of Allergic Manifestations At 5 Years of Age
The present study is a 5-year follow-up of the Allergy Reduction Trial (A.R.T.) birth cohort study of 551 infants at high-risk for allergy. The A.R.T.
- Trial name
- NCT05418491
- Testing
- No intervention is used in the current study. Interventions were given in the original A.R.T. study
- Where
- 3 sites in Bulgaria, Cyprus and 1 more
- Volunteers
- 455 people
- Sponsor
- FrieslandCampina
Ischemic Stroke
Assess the Penumbra System in the Treatment of Acute Stroke
The purpose of this trial is to assess the safety and effectiveness of the Penumbra System as an adjunctive treatment to intravenous (IV) recombinant human tissue plasminogen activator (rtPA)in patients with acute ischemic stroke…
- Trial name
- THERAPY (NCT01429350)
- Testing
- intravenous (IV) recombinant human tissue plasminogen activator (rtPA), Penumbra System
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- Penumbra Inc.
Autism Spectrum Disorders
Neural and Behavioral Effects of Oxytocin in Autism Spectrum Disorders
The current trial aims to explore the neural and behavioral effects of oxytocin in autism spectrum disorders (ASD). Oxytocin is a nonapeptide produced by the paraventricular and supraoptic nuclei of the hypothalamus and is known…
- Trial name
- NCT02940574
- Testing
- Syntocinon (Oxytocin)
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Vascular Access, Coronary Interventions
Vascular Access Registry
The Vascular Access Registry (VARegistry) is a prospective patient registry that will be conducted at the Hemodynamic Laboratory of the Cardiology Clinic of the University General Hospital of Patras.
- Trial name
- VARegistry (NCT06942260)
- Where
- Greece
- Volunteers
- 1,157 people
- Sponsor
- University Hospital of Patras
Ischemic Stroke, Acute, Post-stroke Anxiety
Benson Relaxation for Anxiety, Depression, and Insomnia After Stroke
Stroke is a leading cause of disability worldwide. Many patients experience anxiety, depression, and sleep disturbances in the early recovery phase, which can slow rehabilitation.
- Conditions
- Ischemic Stroke, Acute, Post-stroke Anxiety, Post-stroke Depression, Sleep
- Trial name
- BRT-Stroke (NCT07731282)
- Testing
- Benson Relaxation Technique, Structured Health Education
- Where
- 2 sites in China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Changchun University of Traditional Chinese Medicine
Vitamin D Deficiency
OASIS Study: Vitamin D Deficiency Prevention Among Older Adults in Ireland
Vitamin D deficiency is common. It is caused by limited sun availability together with a low supply of vitamin D in the food system. There is a high prevalence of low vitamin D status around the world.
- Trial name
- OASIS (NCT06705582)
- Testing
- Fortified Bread, Unfortified bread
- Where
- 2 sites in Ireland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University College Cork
Alcohol Use, Underage
JUNTOS Familia Preventive Intervention
The primary objective of this study is to develop and pilot-test a family-based Latino youth alcohol use preventive intervention for Latino youth (ages 14-16) and one of their parents.
- Trial name
- Juntos (NCT05863182)
- Testing
- Juntos Familia Family based intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Substance Use Disorders
The Substance Use and Health Risk Intervention (SUHRI) for Justice-involved Youth
This investigation will adapt and pilot test an integrated health risk-reduction and motivational enhancement intervention for Juvenile Justice (JJ) youth that will ultimately be (after full testing through a subsequent…
- Trial name
- SUHRI (NCT06132282)
- Testing
- Substance Use and Health Risk Intervention (SUHRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Cerebral Palsy (CP)
Ayres Sensory Integration Intervention for Children With Cerebral Palsy
This study will examine whether a 12-week Ayres Sensory Integration (ASI)-based physiotherapy program can improve motor skills and daily functioning in young children with cerebral palsy.
- Trial name
- ASI-CP-PT (NCT07895485)
- Testing
- Ayres Sensory Integration-Based Physiotherapy, Usual Physiotherapy and Rehabilitation
- Volunteers
- 30 people
- Sponsor
- Izgi Miray Demirbag
Accidental Injuries, Global Child Health
The P-KIDs CARE Health Systems Intervention in Tanzania
The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g.
- Conditions
- Accidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System Research
- Trial name
- P-KIDs CARE (NCT06075108)
- Testing
- P-KIDs CARE
- Where
- Tanzania
- Volunteers
- 284 people
- Sponsor
- University of Utah
Down Syndrome, Down Syndrome (Trisomy 21)
Sleep Intervention and Quality of Life in Down Syndrome
Aim 1 of the proposed project will be to adapt the virtual Mindfulness-Based Therapy for Insomnia (MBTI) for individuals with Down syndrome (DS).
- Trial name
- SleepDS (NCT06783725)
- Testing
- Mindfulness-Based Therapy for Insomnia, Wait-list control
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Osteoarthritis Hand
Strategies for Patients With Osteoarthritis, by Using Assistive Technology and Exercises.
Introduction: Osteoarthritis is a disabling disease that can affect 6% to 12% of the adult population and more than a third of people over 65 years of age.
- Trial name
- NCT03173989
- Testing
- Orthosis Exercises Orientation, Orientation
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Early-stage Breast Cancer, Locally Advanced Breast Cancer
Breast Cancer Exercise Intervention Study
This is a 24-week exercise programme consisting of aerobic exercise and muscle strength training, 3 sessions per week. The first 9 sessions are supervised by physiotherapists in person, followed by 63 sessions monitored remotely…
- Trial name
- BREXINT (NCT05957068)
- Testing
- Exercise Programme, Control
- Where
- 3 sites in Singapore
- Volunteers
- 2,156 people
- Sponsor
- National Cancer Centre, Singapore
Chronic Kidney Diseases, Renal Disease
Pain Relief Intervention of Meditation in Renal Disease (PRIMER)
Kidney Disease subjects will be recruited to take part of a mindfulness-based stress reduction intervention for 8-10 sessions. All subjects will complete a baseline interview, one follow-up at 3 months and the close out interview…
- Conditions
- Chronic Kidney Diseases, Renal Disease, Chronic Kidney Failure, End Stage Renal Disease
- Trial name
- PRIMER (NCT03161197)
- Testing
- Mindfulness-Based Stress Reduction
- Volunteers
- 24 people
- Sponsor
- Weill Medical College of Cornell University
Hypertension
Early-warning Intervention for Heat and Cold in Older Hypertensive Patients: Impact on Blood Pressure and ECG
This cluster-randomized trial, conducted in Tianjin, China, aims to evaluate the effectiveness of integrating a digital health risk early warning tool for heat with self-monitoring.
- Trial name
- NCT06011213
- Testing
- Issuing health risk warning for a heat waves or cold spells, A digital heat or cold health risk early warning tool, Self-monitoring blood pressure and ECG device
- Where
- China
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- Tiantian Li
Anxiety, Depression
Anxiety With Cancer in the Elderly (ACE): A Cognitive-behavioral Intervention
The purpose of this study is to examine the feasibility and acceptability of and patient adherence to a telephone-administered cognitive-behavioral therapy intervention for anxiety in older adults (65 years and older) with cancer…
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT02747160
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Long-Term Care, Caregiver Burden
Holistic Self-Empowerment Care Intervention for Optimized Independent Living and Quality of Life: A Study Protocol
This protocol describes a pilot study evaluating the effectiveness of the Self-Empowerment Care Model in promoting independence and quality of life among frail older adults in Hong Kong.
- Trial name
- NCT06736782
- Testing
- Self-Empowerment Care Intervention Group, Control Group
- Where
- Hong Kong
- Volunteers
- 207 people
- Sponsor
- The University of Hong Kong
Obesity
Workplace Intervention: Activity Monitoring as a Tool for Corporate Wellness and Weight Loss
Is a one-year intervention with Treadmill Desks associated with increased employee daily physical activity and decreased sedentariness.
- Trial name
- NCT01461382
- Testing
- Treadmill Desks
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Diet, Healthy, Diet Habit
Healthy Eating Education for Latinos
This intervention aims to evaluate the efficacy of a pilot educational intervention with deep-structure cultural tailoring for Latino ethnic groups on diet quality compared to general, surface-level healthy-eating messages.
- Conditions
- Diet, Healthy, Diet Habit, Obesity, Blood Pressure
- Trial name
- NCT04724382
- Testing
- Culturally tailored healthy eating advice, Standard healthy eating advice
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
HIV/AIDS
Developing a Patient Navigation Intervention for PrEP Continuum of Care Among Young Latino MSM (PrEParate)
This study aims to help young Latino gay and bisexual men access sexual health information, including PrEP. Participants will be randomly assigned to either the patient navigation or the usual care condition and followed for 6…
- Trial name
- NCT04048382
- Testing
- Patient Navigation, Usual Care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- San Diego State University
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