Clinical trials: Interventions
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
The goal of this clinical trial is to determine the effectiveness of using a freeze-dried wild blueberry powder on cardiometabolic health, cognitive function, and gut microbiota composition in adult women with prediabetes.
- Conditions
- Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Female, Adult, Endothelial Function (Reactive Hyperemia)
- Trial name
- NCT06735651
- Testing
- Wild Blueberry
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Georgia State University
Blood Pressure, Sleep
Multidimensional Sleep Health Intervention for Couples
The goal of this pilot dyadic study is to adapt a multidimensional sleep health (MDSH) intervention, previously disseminated at the individual level, for relationship partners, determine whether it improves sleep health and…
- Conditions
- Blood Pressure, Sleep, Cardiovascular Health
- Trial name
- DREAM-COUPLES (NCT07603245)
- Testing
- Multidimensional Sleep Health Promotion Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Columbia University
Surgical Release of Ai Pulley Trigger Finger
Ultrasound Guided A1 Pulley Release For The Treatment of Trigger Finger
In this randomized, prospective clinical trial, patients with trigger finger or trigger thumb, will be treated with two different methods; ultrasound-guided release of the first annular pulley or open surgical release of A1…
- Trial name
- NCT02830672
- Testing
- Surgical release A1 pulley for Trigger finger of the hand
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI
FFR Driven Complete Revascularization Versus Usual Care in NSTEMI Patients and Multivessel Disease
To compare FFR guided complete revascularization during the index procedure with usual care in non-STEMI patients with multivessel disease.
- Conditions
- Coronary Artery Disease, NSTEMI - Non-ST Segment Elevation MI, Fractional Flow Reserve, Myocardial, Myocardial Revascularization
- Trial name
- SLIM (NCT03562572)
- Testing
- Ischemia driven revascularization, Usual care group
- Where
- 9 sites in Czechia, Hungary and 1 more
- Volunteers
- 476 people
- Sponsor
- Zuyderland Medisch Centrum
Stroke
Effects of Three Types of Dual-task Interventions on Dual-task Walking Performance of Stroke Patients
The objective of this study is to investigate psychometric properties of dual-task walking assessments and compare effects of three types of dual-task balance interventions on dual-task walking for stroke patients.
- Trial name
- NCT03614195
- Testing
- MCDTT, MDTT, CDTT
- Where
- Taiwan
- Volunteers
- 54 people
- Sponsor
- Chang Gung University
Cerebral Small Vessel Diseases, Cognitive Impairment
Lacunar Intervention Trial 1 (LACI-1)
Phase II pilot randomised, factorial, short term dose escalation, open label, blinded intermediary endpoint trial, in two hospital centres in the UK, of tolerability and safety of cilostazol, isosorbide mononitrate, both or…
- Conditions
- Cerebral Small Vessel Diseases, Cognitive Impairment, Stroke
- Trial name
- Prevent-SVD (NCT02481323)
- Testing
- isosorbide mononitrate, cilostazol
- Where
- 2 sites in United Kingdom
- Volunteers
- 57 people
- Sponsor
- University of Edinburgh
Psychological Distress, Malnutrition, Child
Transforming Health and Resilience in Vulnerable Environments: Mental Health, Psychosocial Support, and Climate-Smart Farming in Nakivale
The study aims to evaluate if enhancing the mental health of refugee mothers can make them better able to implement new farming methods that are meant to improve food security in the face of climate change.
- Conditions
- Psychological Distress, Malnutrition, Child, Dietary Deficiency, Mental Health
- Trial name
- THRIVE (NCT06425523)
- Testing
- Home Gardening Intervention (HGI), Self-Help Plus (SH+), Enhanced Usual Care (EUC)
- Where
- Uganda
- Volunteers
- 904 people
- Sponsor
- Uppsala University
Physical Activity, Behavior
A Walking Intervention Through Text Messaging
The purpose of this study is to develop and evaluate adaptive goal setting and feedback interventions (Adaptive Interventions) to promote physical activity behaviors and compare it to static physical activity interventions…
- Conditions
- Physical Activity, Behavior, Overweight, Motor Activity
- Trial name
- WalkIT (NCT02053259)
- Testing
- Adaptive Goals, Reinforcement, Static Goals
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Coronary Artery Disease
Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.
Femoral artery approach to perform coronary procedures is considered the standard technique for vascular access due to optimal catheter control, lower thromboembolic complications and immediate access due to the large diameter of…
- Trial name
- NITRAD-Sub (NCT03304496)
- Testing
- Nitroglycerin 100 MCG/ML Injectable Solution, Saline Solution
- Where
- Mexico
- Volunteers
- 1,400 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Chronic Pain
Singing for Chronic Pain, a New Intervention for the Management of Chronic Pain
The aim of the project is to determine the feasibility of delivering a Singing for Chronic Pain (SCP) programme to patients with chronic pain attending a pain clinic.
- Trial name
- NCT04111861
- Testing
- Singing
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Royal Cornwall Hospitals Trust
Depression, Anxiety, Mental Health Issue
Clinical Outcomes of a Digital Mental Health Intervention for Moderate/Severe Depression and Anxiety
A digital mental health intervention (BetterHelp, Mountain View, CA) provides users with access to online therapy care for treatment of depression and anxiety.
- Conditions
- Depression, Anxiety, Mental Health Issue, Mental Health Wellness 2
- Trial name
- NCT07081061
- Testing
- BetterHelp
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Teladoc Health
Traumatic Brain Injury
Acute Cognitive and Neurobehavioral Intervention: Efficacy Evaluation
To learn more about behavior and everyday functioning after brain injury, and to learn if behavior and functioning gets better with more education about changes after brain injury.
- Trial name
- NCT00205569
- Testing
- First Steps Educational Curriculum
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Virginia Commonwealth University
Melanoma
Melanoma Perception and Health Literacy in People of Color
This study will examine the effectiveness of a targeted, health literate educational intervention for people of color compared to a standard melanoma education pamphlet for increasing knowledge and promoting early melanoma…
- Trial name
- NCT02437305
- Testing
- ABCDEs of Melanoma Skin Cancer, ABCDEs of Melanoma
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Smoking Cessation, Thoracic Surgery
Smoking Cessation in the Surgical Pathway Before Major Lung Surgery
This is a feasibility study of a personalised, integrated smoking cessation in the surgical pathway in patients undergoing major elective thoracic surgery when compared to usual care of standard community/hospital based NHS…
- Trial name
- MURRAY (NCT04190966)
- Testing
- Integrated Behavioural therapy, Integrated Pharmacotherapy, Integrated Web-based application
- Volunteers
- 120 people
- Sponsor
- University of Birmingham
Non-Small Cell Lung Cancer (NSCLC)
Digital Lifestyle Intervention for Lung Cancer Survivors
The aim of this study is to assess the efficacy of a digital lifestyle intervention in non-small cell lung cancer (NSCLC) survivors on health-related quality of life (HRQoL) over three months.
- Trial name
- QUALUCA (NCT05819346)
- Testing
- Lifestyle
- Where
- 4 sites in Switzerland
- Volunteers
- 21 people
- Sponsor
- Kai-Uwe Schmitt, PhD, MEng, ICID
Rumination, Stress, Psychological
Testing a Digital Intervention for Adolescents
Teen participants (ages 13-17) will be randomly assigned to either an experimental (the Happify Teens digital platform), or a waitlist control group. The study includes an 8-week intervention period and a 1-month follow up period.
- Trial name
- NCT04567888
- Testing
- Happify Teens
- Where
- United States
- Volunteers
- 353 people
- Sponsor
- Happify Inc.
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Emotional Distress
Mechanisms of Mindfulness Intervention：Rumination Behavioral Experiments
This study hopes to explore whether the changes in rumination exhibited in behavioral experiments mediates the effects of mindfulness intervention on alleviating emotional distress
- Trial name
- NCT06722573
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)-normal version
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Peking University
Child Abuse
A Medical Home-Based Intervention to Prevent Child Neglect in High-Risk Families
Child maltreatment, particularly neglect, disproportionally affects low-income children with special health care needs (CSHCN) and has serious short and long-term consequences.
- Trial name
- NCT02857673
- Testing
- Child Abuse Prevention Problem Solving, Active Control Group
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Infant Sleep Problem
The Role of Circadian Rhythm in the Effect of Sleep Intervention on Obesity Prevention in Early Childhood
Over the last 40 years, obesity has increased dramatically among all age groups, especially in infants and young children, and became an important global public health challenge, thus early prevention is the highest priority.
- Trial name
- NCT05159141
- Testing
- Behavioral sleep intervention
- Where
- China
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.