Clinical trials: Interventions
Arthritis Knee, Arthritis Hip
Developing an Opioid Taper Intervention Before Total Joint Arthroplasty
The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery.
- Conditions
- Arthritis Knee, Arthritis Hip, Chronic Pain
- Trial name
- NCT05788016
- Testing
- opioid taper
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Colorectal Cancer Metastatic
Feasibility of 2 Interventions to Reduce Fatigue in Patients With Chemotherapy for Metastatic Colorectal Cancer
In patients with colorectal cancer, fatigue ranks as the number one chemotherapy-related adverse event, with 75% of patients experiencing grade 3-4 physical and psychological consequences.
- Trial name
- COLOFIGHT (NCT04999306)
- Testing
- Hypnosis, CBT
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Institut du Cancer de Montpellier - Val d'Aurelle
Healthy
YouTube-Delivered Physical Activity Intervention
This study will be an 8-week randomized controlled trial examining the effects of a YouTube-delivered aerobic and muscle strengthening physical activity intervention on university students' physical activity, fitness, sleep…
- Trial name
- NCT04499547
- Testing
- YouTube-delivered aerobic and muscle-strengthening physical activity intervention
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Functional Neurological Disorder
Psychoeducation Group Intervention for FND
This study aims to assess the feasibility of running a brief psychoeducation group intervention in an outpatient setting to assess the practicalities and benefits of offering this type of intervention for both clinicians and…
- Trial name
- NCT03857347
- Testing
- Psychoeducation Group for FND
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Edinburgh
COVID-19
Educational Interventions for Surgeons During COVID-19 Pandemic: Cross-sectional, E-survey
The coronavirus disease 2019 (COVID-19) pandemic required a rapid surge of healthcare capacity to face a growing number of critically ill patients.
- Trial name
- EDUCOVID (NCT04732858)
- Testing
- Cross sectional e-Survey on surgeons exposed to any educational intervention
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
End Stage Renal Disease on Dialysis
Nutritional Interventions in Peritoneal Dialysis Patients with Hypoalbuminemia
Inadequate dietary protein intake is well-known cause of hypoalbuminemia in dialysis population. Protein loss into dialysate and increased catabolic state due to uremic milieu or inflammation worsened hypoalbuminemia, hence high…
- Trial name
- NCT04546958
- Testing
- Whey protein supplements, Nutritional counseling
- Where
- Taiwan
- Volunteers
- 33 people
- Sponsor
- Far Eastern Memorial Hospital
Axial Spondyloarthritis (AxSpA), Aerobic Exercise
Effect of Aerobic Exercises on Axial Spondyloarthropathy
This study aimed to examine whether aerobic exercises, in addition to home exercises, have anti-inflammatory effects, which are evaluated by disease activity, acute phase reactants, and cytokine levels in axial spondyloarthropathy
- Conditions
- Axial Spondyloarthritis (AxSpA), Aerobic Exercise, Disease Activity
- Trial name
- NCT06699238
- Testing
- Home Exercise, Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Yeşim Ozge Gunduz Gul
Kidney Transplant
Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure
A study to determine the effect on renal function in renal transplant patients with biopsy proven Chronic allograft nephropathy (CAN) nephropathy who are switched from a Calcinerin inhibitor (CI) triple drug regimen to a…
- Trial name
- NCT00223678
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanderbilt University Medical Center
HIV
The Treatment Ambassador Program: A Pilot Intervention to Increase Treatment Initiation
This study will evaluate the feasibility and acceptability of the Treatment Ambassador program - a peer-supported intervention targeting individuals living with HIV who have not started on treatment within at least 3 months of…
- Trial name
- NCT03099707
- Testing
- Treatment Ambassador
- Where
- South Africa
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Pregnancy Related, Sexually Transmitted Diseases
Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth
This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program.
- Conditions
- Pregnancy Related, Sexually Transmitted Diseases, Adolescent Behavior
- Trial name
- Yes and Know (NCT06581536)
- Testing
- Yes and Know curriculum, Nutrition Education for Adolescents
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- ETR Associates
HIV, Hepatitis C
Intervention to Improve HCV Treatment Uptake and Adherence in HIV/HCV Coinfection
End-stage liver disease, predominantly due to hepatitis C virus (HCV) infection, is one of the leading causes of death in person living with HIV infection.
- Conditions
- HIV, Hepatitis C, Co-Infection
- Trial name
- NCT02294136
- Testing
- Prep-C, Educational Control
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV
HIV Prevention and Care Interventions for Youth in Uganda
Several studies show that Adolescents and Young Adults (AYA) have poor outcomes along the entire Human Immunodeficiency Virus (HIV) prevention and care cascades compared to adults.
- Trial name
- HIPCY (NCT06474364)
- Testing
- Long-acting Cabotegravir injection, SEARCH-YOUTH
- Where
- Uganda
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- MU-JHU CARE
Neurodegenerative Diseases
Single Arm Clinical Trial of Small Molecule Natural Flavonoid Compounds for Intervention in Neurodegenerative Diseases
1. Explore the effects of natural plant flavonoids on the positive intervention mechanism of neurotransmitter transmission physiological indicators changes (EEG) in the brain of the study subjects; 2.
- Trial name
- NCT05947409
- Testing
- SMARTO ONE
- Volunteers
- 30 people
- Sponsor
- Mei Han
Obesity
On-Line Intervention For Promoting Healthy Habits And Weight Loss In Hypertensive Patients
Efficacy of an Internet-based self-guided intervention for promoting healthy habits and weight loss in hypertensive people with overweight and obesity: A Randomized Controlled Trial
- Trial name
- VIVIR-MEJOR (NCT02445833)
- Testing
- Lifestyle on-line intervention
- Volunteers
- 106 people
- Sponsor
- Universitat Jaume I
Mild Traumatic Brain Injury, Concussion, Mild
Feasibility of a Cognitive Intervention for Youth Post Concussion
The purpose of this study is to evaluate the feasibility and effects of a cognitive intervention for youth following concussion
- Trial name
- NCT03195738
- Testing
- Cognitive Orientation to Occupational Performance (CO-OP)
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Developmental Coordination Disorder (DCD)
Therapeutic Climbing for Children With DCD
This study looks at whether therapeutic climbing - indoor climbing activities guided by therapists - can help children with Developmental Coordination Disorder (DCD).
- Trial name
- Climbing TDC (NCT07609563)
- Testing
- CO-OP-based group therapeutic climbing intervention
- Volunteers
- 16 people
- Sponsor
- Université de Sherbrooke
Percutaneous Coronary Intervention, Virtual Reality
Pain During Femoral Sheath Removal in Patients Undergoing Percutaneous Coronary Intervenion
It is to examine the effect of virtual reality and ice application on the pain level due to femoral sheath extraction.
- Conditions
- Percutaneous Coronary Intervention, Virtual Reality, Nursing Caries, Cryotherapy
- Trial name
- NCT06445387
- Testing
- Virtual Reality Glasses, Ice Application Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Amasya University
Autism
T-ABA Group Based Early Intervention For Parents of Children With ASD
This study is a 10-week, randomized, parallel groups design which will evaluate the efficacy of T-ABA with combined parent training and individual child sessions versus T-ABA with individual sessions alone.
- Trial name
- T-ABA (NCT02202421)
- Testing
- Targeted Applied Behavior Analysis (T-ABA)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The Cleveland Clinic
Parenting, Parent-Child Relations
Parenting Young Children Study
Opioid use is rising at unprecedented levels and has reached epidemic proportions in some areas of the country, particularly rural areas.
- Conditions
- Parenting, Parent-Child Relations, Opioid Misuse, Opioid Use Disorder
- Trial name
- NCT05180487
- Testing
- Family Check-Up
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Nursing, Students
Effectiveness of Web-based Genomic Nursing Education Intervention
There is a research gap of integrating genomics into nursing practice, education and research. Nursing students seldom use genetic-genomic data for understanding the individuality of patients and utilize this in delivering…
- Trial name
- NCT03963687
- Testing
- Standard Nursing Education Intervention, New Nursing Education Intervention
- Where
- Finland
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
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