Clinical trials: Interventions
PostPartum Depression
The Effect of Exercise on Preventing PostPartum Depression
The purpose of this study is to examine the feasibility and efficacy of an exercise intervention for the prevention of postpartum depression.
- Trial name
- NCT00961402
- Testing
- Wellness Control, Exercise Intervention
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Stress, Psychological, Loneliness
Ecological Momentary Assessment and Text Message Intervention for Stress Management
Feasibility and acceptability of an Ecological Momentary Assessment (EMA) compared with an EMA plus automated text message intervention for stress management
- Conditions
- Stress, Psychological, Loneliness, Covid19, Stress
- Trial name
- NCT04907942
- Testing
- EMA + EMA and FACE Stress, EMA Alone
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Click Therapeutics, Inc.
Type 1 Diabetes Mellitus
PRISM for Adolescents With Type 1 Diabetes
It is well-known that adolescents with type 1 diabetes are at high risk for elevated diabetes-specific distress and poor glycemic control.
- Trial name
- NCT03847194
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 2 sites in United States
- Volunteers
- 172 people
- Sponsor
- Seattle Children's Hospital
Chronic Obstructive Pulmonary Disease
Smart Telehealth Exercise Intervention to Reduce COPD Readmissions
This is a prospective randomized controlled study to test the hypothesis that neuromuscular electrical stimulation (NMES) and remote pulmonary rehabilitation at home offered via a smart technology, called Smart TeleHealth…
- Trial name
- NCT03089853
- Testing
- Neuromuscular electrical stimulation (NMES)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Alabama at Birmingham
Kidney Failure, End Stage Renal Disease
Enhancing the Cardiovascular Safety of Hemodialysis Care (Dialysafe)
The purpose of this study is reduce episodes of intradialytic hypotension, low blood pressure during a hemodialysis session, in patients with End Stage Renal Disease (ESRD).
- Conditions
- Kidney Failure, End Stage Renal Disease, Hypotension, Cardiovascular Diseases
- Trial name
- Dialysafe (NCT03171545)
- Testing
- Patient Activation, Provider Education
- Where
- United States
- Volunteers
- 1,431 people
- Sponsor
- University of Michigan
Type 2 Diabetes
Dynamically Tailored Behavioral Interventions in Diabetes
In this project, the investigators will evaluate the efficacy of a novel approach to personalizing behavioral interventions for self-management of type 2 diabetes (T2DM) to individuals' behavioral and glycemic profiles discovered…
- Trial name
- NCT04226027
- Testing
- T2.coach
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Columbia University
ST Elevation Myocardial Infarction
CArdiac Brief INtervention: A Feasibility Study to Promote Engagement With Cardiac Rehabilitation
Background: An ST-elevation myocardial infarction (STEMI) is a specific type of heart attack. In a previous study, patients requested more mental and emotional support after a STEMI.
- Trial name
- CABIN (NCT05848674)
- Testing
- CArdiac Brief INtervention (CABIN), Refined version of CABIN
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Queen's University, Belfast
Drug Overdose, Opioid-Related Disorders
A Tailored, Peer-delivered Intervention to Reduce Recurring Opioid Overdoses
This project will further develop and test the Tailored Telephone Intervention delivered by Peers to Prevent Recurring Opioid Overdoses (TTIP-PRO), a promising, low-cost, intervention to facilitate entry into medication assisted…
- Conditions
- Drug Overdose, Opioid-Related Disorders, Drug Addiction, Drug Abuse
- Trial name
- TTIP-PRO (NCT02922959)
- Testing
- Peer Intervention, naloxone nasal spray kit, Personally-tailored opioid overdose prevention education (information packet)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Cincinnati
Peripheral Neuropathy
Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients
The purpose of this study is to better understand whether or not children with ALL can complete an exercise program during treatment and whether or not that program may impact peripheral neuropathy.
- Trial name
- Exercise (NCT03430674)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Indiana University
HIV Infection, Alcohol Consumption
Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use
This study is being conducted to assess the acceptability and feasibility of a randomized trial of a 10 week virtual intervention to reduce fall risk in people with HIV who consume alcohol.
- Conditions
- HIV Infection, Alcohol Consumption, Falls, Accidental, Falls
- Trial name
- NCT04804579
- Testing
- Fall Prevention Intervention
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Boston University
Stigmatization, Obesity
Psychological Intervention to Reduce Weight Bias Internalization
This is a randomized controlled trial to test the effects on WBI of a novel psychological intervention combined with standard behavioral weight loss (BWL) treatment, as compared to BWL alone.
- Conditions
- Stigmatization, Obesity, Weight Loss
- Trial name
- NCT03572218
- Testing
- BWL, BIAS
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Pennsylvania
Dysphagia, Oropharyngeal
AspiRATE: Novel Intervention to Acoustically Detect Silent Aspiration in Acquired Dysphagia.
This study will investigate whether silent aspiration during swallowing can reliably be detected using acoustic signal processing plus pulse oximetry.
- Trial name
- AspiRATE (NCT03676582)
- Testing
- Acoustic analysis plus pulse oximetry
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Severe Obstructive Sleep Apnea (Apnea Hypopnea Index > 30 Events/Hour), Hypertension
Study of Cardiovascular Disease and Obstructive Sleep Apnea
The purpose of this study is to determine if two medicines (allopurinol and losartan) can influence heart and blood vessel health compared to placebo in patients with sleep apnea who are using continuous positive airway pressure…
- Trial name
- CVD/OSA (NCT01637623)
- Testing
- Losartan, Allopurinol
- Where
- 4 sites in United States
- Volunteers
- 87 people
- Sponsor
- University of Wisconsin, Madison
Stress-related Changes in Inflammation
Academic Stress and Proinflammatory Cytokines: Omega-3 Intervention
This study is designed to examine the effects of fish oil on immune function and mood in medical students.
- Trial name
- NCT00519779
- Testing
- omega-3 supplementation
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Multiple Sclerosis
Cognitive Behavioral Therapy, Modafinil, or Both for Multiple Sclerosis Fatigue
This clinical trial will compare the effectiveness of 3 treatments for fatigue in Multiple Sclerosis: 1) a commonly used behavioral treatment strategy (telephone-based cognitive behavioral therapy), 2) a commonly used medication…
- Trial name
- COMBO-MS (NCT03621761)
- Testing
- Telephone-based Cognitive Behavioral Therapy, Modafinil
- Where
- 2 sites in United States
- Volunteers
- 343 people
- Sponsor
- University of Michigan
Acute Myocardial Infarction
COOL AMI EU Pivotal Trial to Assess Cooling as an Adjunctive Therapy to PCI In Patients With Acute MI (Phase A)
The objective of this trial is to evaluate the safety and effectiveness of therapeutic hypothermia, using the ZOLL Proteus IVTM System, as an adjunctive therapy for patients presenting with acute anterior myocardial infarction…
- Trial name
- NCT03173313
- Testing
- Intravascular permissive hypothermia as an adjunct to PCI
- Where
- Slovenia
- Volunteers
- 111 people
- Sponsor
- ZOLL Circulation, Inc., USA
Urinary Incontinence, Urge
Slow Paced-Respiration Intervention to Reduce Incontinence Trial (SPIRIT)
Urgency incontinence is a common and burdensome problem in women. Current treatments for this condition, while effective, are associated with potentially disabling side effects and high rates of discontinuation.
- Trial name
- SPIRIT (NCT01048424)
- Testing
- RESPeRATE, Urinary Incontinence Pamphlet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Research Awareness
Awareness Enhancing Interventions
The purpose of this study is to determine if increasing awareness and, thus, enhancing positive attitudes about research, prior to recruitment attempts, will increase participation in cancer clinical research among African…
- Trial name
- AWEI (NCT04683510)
- Testing
- Navigation - Study Specific - Researcher Voice, Navigation - Study Specific - Cancer Survivor Voice, Navigation - Research General - Researcher Voice
- Where
- 2 sites in United States
- Volunteers
- 4,451 people
- Sponsor
- University of Tennessee
Type2 Diabetes
A Mobile Health Intervention to Reduce Diabetes Disparities in Chinese Americans
Chinese Americans are one of the fastest growing immigrant groups in the US, who suffer disproportionately high type 2 diabetes (T2D) burden and have poorly controlled T2D.
- Trial name
- NCT03557697
- Testing
- Standard of Care, SMS Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
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