Clinical trials: Interventions
Gout, Hyperuricemia
Probiotics for Gout / Hyperuricemia: A Randomized, Intervention, Parallel Controlled, Multicenter Clinical Trial
Under the premise of double-blind and non-interference clinical treatment, to evaluate the clinical efficacy and safety of probiotic Lactobacillus Zhang combined with routine treatment for gout hyperuricemia.
- Trial name
- NCT04199325
- Testing
- Probiotics, uric-acid-lowering drug
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Affiliated Hospital of Inner Mongolia Medical University
Advanced Cancer
Pilot Trial of Spiritual Care Interventions for Patients With Cancer
This is a pilot trial of the effects of spiritual care interventions on spiritual well-being and readiness to engage in advance care planning (ACP) among black patients with advanced cancer recruited from outpatient settings to…
- Trial name
- NCT06811376
- Testing
- Spiritual Care Intervention #1, Spiritual Care Intervention #2
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Weill Medical College of Cornell University
Abuse Neglect Social, Deprivation, Maltreatment Syndrome (Infant or Child)
Nursing Led Interdisciplinary Intervention in Prevention of Girl Child Mortality and Maltreatment
In Northern India, skewed sex ratios, female feticide and higher child mortality rates for girls have become serious concern. The female child mortality as a result of son preference have increased during the last several…
- Trial name
- NCT02279368
- Testing
- Family Counselling and safeguarding
- Where
- 3 sites in India
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Adwin Life Care
The Focus is to Investigate Effect of an Educational Video on Fecundity Knowledge Among Young Adults
Young Adults' Fecundity Knowledge and Fertility Intentions and Reproductive Behavior
This RCT investigates the impact of an educational video on fecundity knowledge among young adults. The video discusses several risk factors associated with fecundity, such as age and smoking.
- Trial name
- NCT06631950
- Testing
- Educational intervention
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infertile Women Undergoing IVF or ICSI
Postbiotic Intervention on Vaginal Microbiota
This study investigates the effects of postbiotic intervention on vaginal microbiota in infertile patients. Using a pre-post test design, we will enroll 15 women aged 30-45 years with at least two IVF failures.
- Trial name
- NCT07278024
- Testing
- postbiotics
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Chronic Pain, Musculoskeletal Pain
Empowered Relief for Caregivers
This study is testing a new program called Empowered Relief for Caregivers (ER-CY), designed to support caregivers of children and teens who live with chronic pain. ER-CY is a single two-hour class delivered online.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Fibromyalgia, Neuropathic Pain
- Trial name
- ER-CY (NCT07636980)
- Testing
- Empowered Relief for Caregivers (ER-CY)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Grief
A Finding Balance Writing Intervention for Older Bereaved Caregivers
The overall purpose of this study is to develop and pilot-test a theory-based psychosocial supportive "finding balance" intervention for older, bereaved spousal caregivers of a palliative cancer patient.
- Trial name
- NCT01416779
- Testing
- Writing Intervention
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Chronic Kidney Disease, Diet Interventions
Dine and DASH Into Wellness Pilot Study
The purpose of this study is to determine the feasibility and acceptability of a16-week diet coaching program enhanced with cooking classes to improve adherence to the Dietary Approaches to Stop Hypertension (DASH) diet among…
- Conditions
- Chronic Kidney Disease, Diet Interventions, Disease Prevention
- Trial name
- NCT07175896
- Testing
- Immediate delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program, Delayed delivery of low-sodium DASH (Dietary Approaches to Stop Hypertension) diet group coaching plus hand-on cooking program
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
Pulmonary Embolism
Implementation of a Structured Post-pulmonary Embolism Follow-up Model
Venous thromboembolism (VTE), clinically presenting as deep vein thrombosis or pulmonary embolism (PE) is the third most frequent cardiovascular disease and is associated with substantial short- and long-term morbidity and…
- Trial name
- NCT06037096
- Testing
- Attend-PE model
- Where
- Denmark
- Volunteers
- 2,000 people
- Sponsor
- Aalborg University Hospital
Migraine Headache
Effectiveness of Education and Relaxation Program on Migraine Related Disability in Patients Attending Headache Clinic
Migraine causes severe impairment in quality of life (QOL) both during and between attacks. Migraine also increases absenteeism, reduces productivity at work as well as at home, disrupts social and family relationships, also is…
- Trial name
- NCT05039996
- Testing
- education and relaxation program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Metabolic Syndrome, Hypertriglyceridemia
Effects of Diet Interventions on Monocytes in Metabolic Syndrome
Subjects with hypertriglyceridemia and metabolic syndrome are being recruited and receive diet interventions with either a high-saturated fat diet or a low-fat high protein diet for 4 days (days 1-4) and a breakfast on day 5.
- Trial name
- NCT03591588
- Testing
- diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Chronic Heart Failure, Aging
Comparing the Effects of Combining Cognitive and Physical Exercise Training on Cognition, and Cerebral Blood Flow Regulation in Men and Women With Chronic Heart Failure
The objective of this project is to assess the effects of combined physical exercise and cognitive training interventions on cognitive and brain health in patients with heart failure (HF).
- Trial name
- ReCARDIO (NCT04970888)
- Testing
- Cognitive training, Exercise training, Usual care
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Montreal Heart Institute
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Procedural Pain, Heel Prick
ShotBlocker and Warm Gel Pack During Neonatal Heel Prick (HEAL)
This study evaluated the effects of ShotBlocker and a warm gel pack on pain, comfort, and physiological parameters during heel prick testing in healthy term newborns.
- Conditions
- Procedural Pain, Heel Prick, Newborn
- Trial name
- HEAL (NCT07686627)
- Testing
- ShotBlocker, Warm Gel Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Marmara University
HIV-1-infection
Observational PIC Destination Cohort
This study is being done to see if people who control HIV without antiretroviral therapy (ART) after receiving an intervention can remain off ART safely.
- Trial name
- NCT05985642
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
HIV, Opiate Dependence
Project FIRST - Financial Incentives to Reduce Substance Use and Improve Treatment
This study will test whether contingency management (monetary vouchers contingent on abstinence from drugs) that reinforces one behavior (achieving abstinence from drugs) leads to improved outcomes in other related behaviors…
- Trial name
- Project FIRST (NCT01376570)
- Testing
- Abstinence-reinforcing contingency management intervention, Performance Feedback intervention
- Where
- 3 sites in United States
- Volunteers
- 242 people
- Sponsor
- Albert Einstein College of Medicine
Depression
Cognitive Behavioural Couple Intervention Therapy for Chinese Couples With a Depressed Partner
Understanding depression from a relational perspective maybe more meaningful in Chinese culture due to the different values and beliefs among Chinese comparing to those of the Western cultures.
- Trial name
- NCT04590573
- Testing
- Cognitive behavioural couple therapy (CBCT), Emotion focused couple therapy (EFCT), Wait-list control (Control)
- Where
- Hong Kong
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Low Executive Function in Children
Modeling and Testing Change in Mental Abilities in Childhood
Children with low executive function, working memory and attention skills in childhood not only do poorly at school, but also go on to do poorly on social, health, and financial indicators in adulthood.
- Trial name
- NCT02459873
- Testing
- Computer games to assess change in executive function skills
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Major Depressive Disorder
Early Versus Delayed Switch in Medication in Patients With Major Depressive Disorder
This study investigates two different approaches to the change in antidepressant treatment when an initial treatment is not effective: early intervention or delayed intervention. Two hypothesis will be tested: 1.
- Trial name
- NCT00810069
- Testing
- Duloxetine Hydrochloride, Escitalopram
- Where
- 60 sites in Denmark, France and 9 more
- Volunteers
- 840 people
- Sponsor
- Eli Lilly and Company
Frailty, Sarcopenia
A Randomized Control Trial of an Intervention to Reverse Frailty and Enhance Resilience Through Exercise and Education
Resistance training done at home and protein supplementation may be the most effective and easiest to implement interventions to reverse frailty and build resilience.
- Trial name
- REFEREE (NCT04628754)
- Testing
- Exercise and protein
- Where
- Ireland
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University College Dublin
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