Clinical trials: Interventions
Heart Disease
Vet-Harts Pilot Intervention for Veterans With Coronary Heart Disease
The purpose of this research study is to survey patients to learn about their beliefs and behaviors related to the management of heart disease and to discuss options for making healthy lifestyle changes.
- Trial name
- VHPI (NCT01566214)
- Testing
- Motivational Interview
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- VA Office of Research and Development
Dementia, Family Caregiver
German Adaptation of REACH II
The purpose of the present study is to adapt, to implement and to evaluate an support program for family caregivers of patients suffering from Alzheimers'Disease (AD).
- Trial name
- GE-REACH (NCT01690117)
- Testing
- GE-REACH-program
- Where
- Germany
- Volunteers
- 92 people
- Sponsor
- University of Leipzig
Smoking Cessation
Extended Treatment for Smoking Cessation
Adult smokers (21-65) and adolescent smokers (18 - 21) years of age residing in Alameda and Santa Clara counties will serve as the target population for this study.
- Trial name
- NCT01330043
- Testing
- Bupropion, Nicotine patch, Varenicline
- Where
- United States
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sleep, Pain
A Personalized Behavioral Intervention for Older Adults With Musculoskeletal Pain and Sleep Complaints
It is well recognized that physical activity/exercise is an effective intervention to improve sleep, reduce pain and improve function in a variety of pain conditions.
- Trial name
- NCT03921840
- Testing
- ELDERFITNESS, Control
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Opioid-use Disorder
Disclosure Intervention for People in Recovery From Opioid Use Disorder
Many people with substance use disorders struggle with decisions regarding whether to disclose to others that they have a history of substance use and/or are in recovery.
- Trial name
- NCT04836247
- Testing
- Disclosing Recovery: A Decision Aid and Toolkit, Mindfulness
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Delaware
Malaria,Falciparum, Gametocytes
Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2
This is a single-center, open label study. The primary aim of this project is to develop a controlled human malaria infection transmission model ("CHMI-trans") or "challenge model" to evaluate the capacity of vaccines, biologics…
- Conditions
- Malaria,Falciparum, Gametocytes, Controlled Human Malaria Infection, Transmission
- Trial name
- CHMI-trans2 (NCT03454048)
- Testing
- Piperaquine (low dose), Piperaquine (high dose), Sulfadoxine pyrimethamine
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Caregiver Burnout
CuidaTXT: a Text Message Dementia-caregiver Intervention for Latinos
Latino families with dementia experience substantial disparities in access to caregiver support compared to their non-Latino white peers, putting them at an increased risk for negative emotional, physical and financial outcomes.
- Trial name
- CuidaTXT (NCT04316104)
- Testing
- CuidaTXT
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Hematologic Malignancy, Hematopoietic/Lymphoid Cancer
A Proof-of-Concept Trial of a Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients
The goal of this research study is to find out if a novel phone-based positive psychology intervention that focuses on improving health behaviors and positive emotions can help improve mood, health related quality of life, and…
- Conditions
- Hematologic Malignancy, Hematopoietic/Lymphoid Cancer, Blood Cancer
- Trial name
- NCT03654404
- Testing
- Positive Psychology Intervention
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Brigham and Women's Hospital
Behavior Problem, Parenting
Adapting a Parenting Intervention to Promote Healthy Screen Time Habits in Young Children With Behavior Problems
This project is a study funded by the National Institute of Child Health and Human Development to develop and pilot test an adapted parenting intervention to decrease excessive/inappropriate screen media use in young children…
- Trial name
- NCT05287685
- Testing
- Screen media adapted School Readiness Parenting Program, School Readiness Parenting Program
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Florida International University
Coronavirus
COVID-19 Risk Reduction Among African American Parishioners
African American adults, specifically those managing chronic disease and social isolation, are one of the most vulnerable groups susceptible to COVID-19.
- Trial name
- NCT04542343
- Testing
- Change in knowledge, motivation, skills, resources
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Coronary Artery Disease
The Dual Antiplatelet Therapy Study (DAPT Study)
The DAPT Study is a double blind randomized controlled trial intended to determine the appropriate duration for dual antiplatelet therapy (the combination of aspirin and a second anti-clotting medication) as well as the safety…
- Trial name
- NCT00977938
- Testing
- Clopidogrel & Aspirin, Prasugrel & Aspirin
- Where
- 256 sites in United States, Australia and 8 more
- Volunteers
- 25,682 people
- Sponsor
- Baim Institute for Clinical Research
Retinopathy of Prematurity
Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)
Phase 2, open-label, randomized, multi-center studies in infants and premature infants are necessary to determine treatment and preventative strategies for ROP.
- Trial name
- SPIPROP (NCT02344225)
- Testing
- Caffeine citrate, Ibuprofen, Ketorolac
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
Risk Behavior, HIV/AIDS
Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and…
- Conditions
- Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
- Trial name
- CHRP-BB (NCT03282890)
- Testing
- CHRP-BB
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Connecticut
COVID-19 Vaccines, COVID-19 Pandemic
Getting to Yes, Michigan! (G2YMI)
This study entitled Community-Centered Interventions for Improved Vaccine Uptake for COVID-19 (CIVIC): Getting to Yes, Michigan!, is designed to increase vaccine uptake among populations that experience COVID-19 related…
- Trial name
- G2YMI (NCT05096260)
- Testing
- Motivational Interviewing based SMS/MMS and web content
- Where
- United States
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Falls (Accidents) in Old Age
Evaluating Technology-Based Fall Prevention Interventions
Approximately one in three older adults fall annually and it is the primary cause of traumatic injury in older adults. While exercise and balance programs have been shown to be effective in reducing fall risk, maintaining…
- Trial name
- FaCT2 (NCT03190460)
- Testing
- Cognitive Training, Technology-based Education
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Washington
Contraception, Sexually Transmitted Infections
Connecting Healthy Women: Examining the Effect of an Intervention From the Effect of Being Reachable
The investigators propose to test a community-developed and targeted intervention that employs community health workers (CHWs) as aides to newly Medicaid-insured women.
- Conditions
- Contraception, Sexually Transmitted Infections, Cervical Cancer
- Trial name
- NCT02157168
- Testing
- Community health worker
- Where
- United States
- Volunteers
- 2,267 people, healthy volunteers welcome
- Sponsor
- University of Arizona
HIV Infections, Sexually Transmitted Diseases
Multi-component Intervention to Train Providers to Promote PrEP for Girls and Women in the Deep South
The goal of this study is to adapt evidence-based curriculum on HIV epidemiology and PrEP prescription to train family medicine physician trainees to take a thorough sexual history and discuss HIV/STI prevention and PrEP options…
- Trial name
- PrEP Pro (NCT06487390)
- Testing
- PrEP Pro training intervention
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama at Birmingham
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Loneliness
Modifiers and Mechanisms of Loneliness Interventions
A specific aim of this research is to identify the role of emotion regulation in response to social threat in caregivers' response to a behavioral coaching intervention for loneliness.
- Trial name
- NCT05812989
- Testing
- Social Engage Coaching, Connect for Caregivers
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Rochester
HIV
Online Social Networking for HIV Prevention
In this randomized controlled trial, we will identify social networks on Facebook, an randomly assign each network to control or intervention status.
- Trial name
- NCT00725959
- Testing
- Online social networking HIV prevention
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- Colorado School of Public Health
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