Clinical trials: Intestinal Diseases, Parasitic
Ulcerative Colitis, Ulcerative Colitis Exacerbation
Role of Intestinal Protozoa and Helminths in the Course of Ulcerative Colitis
Ulcerative colitis (UC) is a chronic inflammatory disorder of the gastrointestinal tract of unknown etiology. UC is characterized by recurring episodes of inflammation limited to mucosal and submucosal layers of the colon.
- Conditions
- Ulcerative Colitis, Ulcerative Colitis Exacerbation, Protozoan Infections, Helminth Infection
- Trial name
- NCT03441893
- Testing
- parasitological diagnostics (coproscopy), Nitazoxanide 500Mg Oral Tablet, Mesalazine 250Mg Tablet and nitazoxanide 500Mg Oral Tablet
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Research Institute of Epidemiology, Microbiology and Infectious Diseases, Uzbekistan
Helminthiasis, Diarrhea
Spillover Effects of Water, Sanitation, and Hygiene Interventions on Child Health
The purpose of this study is to measure whether a combined water, sanitation, and hygiene intervention leads to improved health of children who did not receive the intervention themselves and who live within a close vicinity of…
- Conditions
- Helminthiasis, Diarrhea, Respiratory Infection
- Trial name
- NCT02396407
- Testing
- Combined water, sanitation, and hygiene
- Where
- Bangladesh
- Volunteers
- 1,789 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Acute Bacterial Infections, Acute Viral Infections
300 Antibody Diagnostic Test Kit
For the development of a Point of Care IVD test kit for acute phase disease detection against a variety of bacterial and viral infections.
- Trial name
- Antibody 300 (NCT01646411)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The Plasma Source
Schistosomiasis
A Phase Ib Study of the Safety, Reactogenicity, and Immunogenicity of Sm-TSP-2/Alhydrogel)(R) With or Without AP 10-701 for Intestinal Schistosomiasis in Healthy Exposed Adults
The study will be conducted as a randomized, controlled, double blind Phase 1b dose-escalating clinical trial in up to 60 healthy adult males and non-pregnant females living in the S.
- Trial name
- NCT03110757
- Testing
- GLA-AF, Hepatitis B Virus Vaccine (Recombinant), Sm-TSP-2/Alhydrogel
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Infections
Education Intervention to Reduce Helminth Infections and Absenteeism in Grade 5 School-children
To efficiently control soil-transmitted helminths (Ascaris, Trichuris, and hookworm), WHO, PAHO, and others recommend the inclusion of an education strategy in school-based deworming programs.
- Trial name
- NCT01085799
- Testing
- Health Education Intervention
- Where
- Peru
- Volunteers
- 1,101 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Intestinal Helminthiasis, Ascariasis
Impact of Repeated Anthelmintic Treatment on the Risk of Malaria in Kenyan School Children
Many school children in Kenya are infected with plasmodia and helminth species and are at risk of coinfection. It has been suggested that the immune response evoked by helminth infections may modify immune responses to plasmodia…
- Conditions
- Intestinal Helminthiasis, Ascariasis, Hookworm, Malaria
- Trial name
- NCT01658774
- Testing
- Albendazole, Vitamin C
- Where
- Kenya
- Volunteers
- 2,377 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Intestinal Helminthiasis, Diarrhea
The Impact of Anthelmintic Treatment on the Incidence of Diarrheal Disease in Vietnamese School Children
Cheap and effective drugs called 'anthelmintics' are routinely administered to children in developing countries to eliminate infections by parasitic helminths.
- Trial name
- NCT02597556
- Testing
- Albendazole
- Where
- Vietnam
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Schistosomiasis, Schistosoma Mansoni
Sm-TSP-2 Schistosomiasis Vaccine in Healthy Ugandan Adults
The study will recruit up to 290 healthy adult males and non-pregnant females into a two-part clinical trial of a vaccine to protect against schistosomiasis caused by infection with S. mansoni.
- Trial name
- NCT03910972
- Testing
- Sm-TSP-2/Alhydrogel® vaccine, Sm-TSP-2/Alhydrogel® vaccine plus AP 10-701, ENGERIX-B Hepatitis B Vaccine
- Where
- Uganda
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Blastocystis Infections
Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis
Blastocystis is an anaerobic unicellular protozoal parasite infecting the gastrointestinal tract of humans and a wide range of animals.
- Trial name
- NCT05580393
- Testing
- RFLP analysis of SSU rRNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
HIV Infections
Surveillance and Medical Help for HIV-infected Intravenous Drug Users in and Out of Prison
It is difficult to detect the intestinal protozoal infections among the HIV-infected persons or travelers diarrhea by using the traditional microscopy or staining methods.
- Trial name
- NCT00739258
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Concomitant Infection of Intestinal Parasites and Helicobacter Pylori
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in…
- Trial name
- NCT05360940
- Testing
- H.pylori stool antigen rapid test and stool parasitological examination
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Blastocystis Infections
Efficacy of Calprotectin as A Marker For the Pathogenicity of Blastocystis Infection
Blastocystis which is commonly found in the gastro-intestinal tract, has been recognized as a non-pathogenic organism for a few decades. It has a variable distribution.
- Trial name
- NCT05724368
- Testing
- Fecal Calprotectin ELISA kit
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Soil-transmitted Helminthiasis, Schistosomiasis
Diagnosis of Neglected Tropical Diseases Among Patients With Persistent Digestive Disorders
NIDIAG is an international collaboration on integrated diagnosis-treatment platforms, funded by the European Commission (EC). NIDIAG aims to develop an improved, patient-centred system for delivering primary health care in…
- Conditions
- Soil-transmitted Helminthiasis, Schistosomiasis, Strongyloidiasis, Shigellosis
- Trial name
- NIDIAGDigest (NCT02105714)
- Testing
- Stool culturing for pathogenic bacteria, Kato-Katz technique, Baermann technique
- Where
- 7 sites in Côte d’Ivoire, Indonesia and 2 more
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Diarrhea
Etiology of Diarrhea in Guinea-Bissau and in Finland
Diarrhoea is the leading cause of death in the world with 2.2 million deaths every year. The majority of deaths are among children in developing countries, but the travellers encounter the disease as well.
- Trial name
- NCT01269554
- Where
- 3 sites in Finland, Guinea-Bissau
- Volunteers
- 920 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Anemia, Intestinal Helminthiasis
A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes
In this study, it is hypothesized that helminth infections modulate immune responses against HIV-1 infection resulting into increased HIV-1 multiplication, faster progression to AIDS and increased episodes of AIDS-related…
- Conditions
- Anemia, Intestinal Helminthiasis, Intestinal Schistosomiasis, Human Immunodeficiency Virus I Infection
- Trial name
- NCT01541631
- Testing
- Praziquantel and Albendazole
- Where
- 2 sites in Tanzania
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Catholic University of Health and Allied Sciences
Vitamin A Deficiency in Children
The Effects of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia
Based on recent nutrition survey (SEANUTS Malaysia) on a total of 3542 Malaysian Children aged between 6 months to 12 years old, 4.4% of the children had vitamin A deficiency.
- Trial name
- NCT03256123
- Testing
- red palm shortening group, palm shortening group
- Where
- Malaysia
- Volunteers
- 651 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Malnutrition, Diarrhea
WASH Benefits Kenya
The purpose of this study is to measure the independent and combined effects of interventions that improve sanitation, water quality, handwashing, and nutrition on child health and development in the first years of life.
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- WASHB-Kenya (NCT01704105)
- Testing
- Water Quality, Sanitation, Handwashing
- Where
- Kenya
- Volunteers
- 8,246 people, healthy volunteers welcome
- Sponsor
- Innovations for Poverty Action
Stunting
Gut Microbiota Stunted Children NTT
NTT Province is on the list of priority areas of high prevalence of stunting, Southwest Sumba, South Middle East, and Kupang district have a stunting prevalence of 36.2%, 34.5% and 48.1% respectively in 2020.
- Trial name
- NCT05119218
- Testing
- No Intervention
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bina Nusantara University
Giardia Lamblia Infection
Vitamin D Estimation With Giardia Lamblia Infections
investigators will take stool and blood samples from two groups of humans :- 1-group A (healthy group negative Giardia or control group),2-group B (positive Giardia or case group)then investigators make estimation for vitamin D…
- Trial name
- NCT04778280
- Where
- 2 sites in Egypt
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Sohag University
HIV Infections, Protozoan Infections
Intestinal Protozoal Infections and Sexual Transmitted Diseases Among Targeted Cohorts
In this two-year study, we will target two high risk groups, including MSM of HIV-infected and those of non-HIV-infected. We will avail the serodiagnosis to detect the potential amebic carriers in both groups; and use microscopy…
- Trial name
- NCT00630162
- Testing
- amoeba
- Where
- Taiwan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital