Clinical trials: Intestinal Microbiota
Endotoxemia, Metabolic Syndrome
Effect of Cranberry and Agaves Extract on Microbiota and Intestinal Health
The growing prevalence of obesity and type 2 diabetes (T2D) is a major public health problem. Recent studies have clearly established that the gut microbiota plays a key role in the investigator's propensity to develop obesity…
- Conditions
- Endotoxemia, Metabolic Syndrome, Glucose Metabolism Disorders, Insulin Resistance
- Trial name
- Phenulin (NCT03800277)
- Testing
- Cranberry, Agaves
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Laval University
Temperament, Sleep
GUTLINK4KIDS Intervention
This study aims to investigate the chronic effects of prebiotic consumption on cognitive, behavioural and gut microbiome outcomes in children aged 3-5 years.
- Conditions
- Temperament, Sleep, Cognition, Emotion Regulation
- Trial name
- GUTLINK4KIDS (NCT07401212)
- Testing
- Prebiotic powder
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Reading
Depression, Anxiety Disorder
Effect of Lactobacillus Plantarum 299v Supplementation on Major Depression Treatment
The aim of the study is to determine the influence of supplementation of probiotic Lactobacillus Plantarum 299V vs. placebo of probiotic during antidepressant monotherapy with SSRI (Selective Serotonin Reuptake Inhibitor) in…
- Trial name
- NCT02469545
- Testing
- Lactobacillus Plantarum 299v, Crystalline cellulose powder, Escitalopram
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Bialystok
Functional Constipation, Irritable Bowel Syndrome Characterized by Constipation
Mode of Action of Moviprep
The University of Nottingham have been developing new, non-invasive magnetic resonance imaging (MRI) techniques to image the bowel.
- Trial name
- NCT01622972
- Testing
- Polyethyleneglycol
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Postbiotics Supplementation
Postbiotics Supplementation, Gut Microbiota Composition, and Exercise-induced Inflammation
This study will investigate the effect of postbiotics supplementation on gut microbiota (GM) composition, exercise-induced oxidative stress and performance following eccentrically biased exercise.
- Trial name
- PostBioExIn (NCT06428656)
- Testing
- Postbiotics supplementation
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Crohn Disease
Effect of Acupuncture on the Microbiota-gut-brain Axis in Crohn's Disease
Multidisciplinary techniques such as multimodal neuroimaging, microbiology, and bioinformatics were applied to study the differences in correlation characteristics between gut microbes, functional brain networks, and peripheral…
- Trial name
- NCT06364722
- Testing
- Acupuncture treatment
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Dietary Habits, Bowel Dysfunction
Fiber and Water Improve Bowel Habit in Humans
Twenty healthy volunteers had their baseline parameters (symptoms, bowel habit, quality of life, fecal characteristics and microbiota) measured during a week of monitoring followed by randomization to a 14 days course of…
- Trial name
- NCT02838849
- Testing
- Fiber, Fiber and Water
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidade de Passo Fundo
Gut Microbiota, Metabolic Syndrome
Effect of Mango on Gut Microbiota and Metabolic Health
Mango is rich in bioactive compounds such as dietary polyphenols and carotenoids, which may explain its beneficial effect on health. Polyphenols accumulate in the gut where they can positively modulate the microbiota.
- Trial name
- NCT03825276
- Testing
- Mango consumption
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Laval University
Irritable Bowel Syndrome
Fructo-oligosaccharides and Irritable Bowel Syndrome
Fructo-oligosaccharides are known as prebiotic ingredients to modulate the composition of the intestinal microbiota and particularly to stimulate the growth of Bifidobacteria.
- Trial name
- NCT00806104
- Testing
- Fructo-oligosaccharides, Maltodextrins
- Where
- 2 sites in France, Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beghin-Meiji
Clinical Infection, Microbial Colonization
Effect of Gut Microbiota and Fecal Inflammatory Marker on Childhood Gastroenteritis
Childhood gastroenteritis establishes gastrointestinal disease and increase the economic burden, and the pediatric population is especially vulnerable to these gastrointestinal infections.
- Conditions
- Clinical Infection, Microbial Colonization, Gastroenteritis, Inflammatory Response
- Trial name
- NCT03856138
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obesity
Long-term Effects of Green Tea on Gut Flora, Fat Absorption, Body Composition and Resting Energy Expenditure
Green tea may have positive effects for weight control and on body composition via several approaches such as a positive effect on the gut flora, a decrease in fat absorption from the intestines and an increase in resting energy…
- Trial name
- NCT01556321
- Testing
- green tea (757 mg/capsule [84.5 mg EGCG + 2.1 mg caffeine ]
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Systemic Lupus Erythematosus (SLE)
Mediterranean Diet and Gut Microbiota in Children With Systemic Lupus Erythematosus
The goal of this clinical trial is to learn if a Mediterranean diet can improve gut microbiota, disease activity, and nutrition in children with systemic lupus erythematosus (SLE).
- Trial name
- NCT07555626
- Testing
- Mediterranean Diet-Based Individual Nutrition Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Gut Microbiota
Westlake Gut Microbiome Study
The Westlake Gut Microbiome study is a prospective cohort study. This project aims to characterize the gut microbiome among Chinese populations from different regions of China, and explore the relationships between gut microbiota…
- Trial name
- NCT04435548
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Westlake University
Healthy
Chronic Cardiovascular and Gut-bacteria Effects of Phenolic Rich Oats in Adults With Above Average Blood Pressure
In this proposed human trial, the investigators aim to establish whether 4 weeks of daily consumption of beta-glucan matched meals providing either a high dose or a moderate dose of oat avenanthramides and phenolic acids leads to…
- Trial name
- NCT02847312
- Testing
- High avenanthramide, phenolic acid, Low avenanthramide, medium phenolic acid, Control
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Reading
Ischemic Stroke, Atherosclerosis
The Gut and Oral Bacteria, Atherosclerosis and Ischemic Stroke Study
The main aim of this project is to demonstrate an association between gut and oral microbiota and their metabolites to carotid atherosclerosis and risk of ischemic stroke.
- Conditions
- Ischemic Stroke, Atherosclerosis, Microbiota
- Trial name
- NCT04803838
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Metabolic Syndrome
Effect of Functional Foods on Gut Microbiota in Metabolic Syndrome
Aim: To study the effect of a combination of functional foods on gut microbiota in subjects with metabolic syndrome. Subjects that met the metabolic syndrome criteria were enrolled in a double-blind, parallel-arm, placebo-control…
- Trial name
- MetS (NCT03611140)
- Testing
- DP
- Where
- Mexico
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Diet Habit
Chestnut Consumption on Modulation of Gut Microbiota and Metabolic Parameters
The chestnut tree (Castanea sativa Mill.) is a species widely cultivated in Portugal, which is a major producer of chestnuts. Nuts are nutritionally interesting, not only because of their content of vitamins, minerals, and…
- Trial name
- CULTIVAR (NCT05705960)
- Testing
- Chestnut
- Where
- Portugal
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Inflammatory Bowel Disease, Colorectal Cancer
Intestinal Microbiota and Colorectal Cancer in Inflammatory Bowel Disease
Build a collection of fecal microbiota in order to determine the characteristics of gut microbiota associated with colorectal cancer in Inflammatory bowel disease (IBD).
- Trial name
- DYSCOLIC (NCT02726243)
- Where
- France
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiometabolic Risk, Abdominal Obesity
Characterization of Gut Microbiota Composition and Activity After a Daily Supplementation of 4.5 g/Day of ChitinGlucan Fibre During 3 Weeks in At-cardiometabolic Risk Volunteers
The aim of this study is to demonstrate the beneficial effects on gut microbiota composition and activity of the diary intake of insoluble fiber (extract from Aspergillus Niger) for three weeks.
- Trial name
- FITACHITIN (NCT03773900)
- Testing
- Kiotransine (chitin-glucan from aspergillus niger)
- Where
- France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Metabolic Disease, Injury of Gastrointestinal Tract
The Effect of Whole Grain on Gut Microbiome and Metabolic Health
Objective: To identify how specific changes of the whole grain content in the diet affect the host-gut microbiome interactions with implications for metabolic health .
- Trial name
- 3G (NCT01731366)
- Testing
- Whole grain, Refined grain
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
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