Clinical trials: Intestinal Neoplasm
Acute Lymphoblastic Leukemia, Pediatric
Physical Exercise and Dairy Probiotics in Childhood Cancer Survivors
The goal of this clinical trial is to to compare the structure of the intestinal microbiome between children shortly after treatment for acute lymphoblastic leukemia (1-3 years after cancer treatment) and healthy controls.
- Trial name
- Exerbioall (NCT05939791)
- Testing
- Lacticaseibacillus paracasei subsp. Paracasei CNCMI-1518, Physical exercise
- Where
- Slovakia
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Comenius University
Colorectal Neoplasms
Unprepped CT Colonography
It is our objective to improve the performance of CTC in the prepared colon, and to validate CTC in the unprepared colon for the detection of colorectal neoplasia.
- Trial name
- NCT00586053
- Where
- United States
- Volunteers
- 1,255 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer, Advanced Adenocarcinoma
Colorectal Cancer and Pre-Cancerous Adenoma Non-Invasive Detection Test Study
This study was a prospective analysis conducted by Geneoscopy Inc. to evaluate the ColoSense test, which is a multi-target stool RNA test for colorectal cancer screening.
- Conditions
- Colorectal Cancer, Advanced Adenocarcinoma, Serrated Polyp
- Trial name
- CRC-PREVENT (NCT04739722)
- Testing
- ColoSense
- Where
- 2 sites in United States
- Volunteers
- 14,263 people, healthy volunteers welcome
- Sponsor
- Geneoscopy, Inc.
Stoma Ileostomy, Stoma Colostomy
The Effect of Education on Self-Efficacy and Adaptation to Stoma of Individuals With Stoma
The aim of this study is to determine the effect of stoma care training given at home via videoconferencing after discharge on the self-efficacy and compliance with stoma of individuals with stoma.
- Conditions
- Stoma Ileostomy, Stoma Colostomy, Self Efficacy, Adjustment
- Trial name
- NCT05531331
- Testing
- At home education via video conferencing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Colorectal Cancer
Maximizing Yield of the Fecal Immunochemical Test for Colorectal Cancer Screening
Colorectal cancer (CRC) is a leading cause of cancer death in the United States. Screening for CRC reduces CRC mortality, yet rates of screening in the United States remain low.
- Trial name
- MY-FIT (NCT01634126)
- Testing
- 1 FIT kit, 2 FIT kit
- Where
- United States
- Volunteers
- 2,761 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Hepatocellular Cancer, Non-small Cell Lung Cancer
Profile of Soluble and Cellular Biomarkers and of Functional Imaging During Antiangiogenic Therapies in Cancer Patients
Tumour angiogenesis has been identified to play a critical role in tumour growth and this knowledge has led to the identification of new targets for cancer therapy.
- Conditions
- Hepatocellular Cancer, Non-small Cell Lung Cancer, Renal Cell Cancer, Colorectal Cancer
- Trial name
- NCT01507740
- Testing
- Avastin, Suntent, Nexavar
- Where
- Austria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Gastrointestinal Disease, Colorectal Cancer
Randomized Controlled Study Comparing Colon Evaluation With The Pure-Vu System To A Standard Colonoscopy In Patients Who Are High Risk For Inadequate Bowel Preparation
The primary objective of this multi-center, prospective, randomized controlled trial is to evaluate the bowel cleansing after Pure-Vu use in outpatient subjects at high risk for inadequate colon preparation as compare to standard…
- Trial name
- RESCue (NCT04285008)
- Testing
- Pure-Vu System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Motus GI Medical Technologies Ltd
Lung Neoplasms, Neoplasm Metastasis
Mediastinal Lymph Node Dissection in Conjunction With Pulmonary Metastasectomy From Colorectal Cancer
To study whether or not total mediastinal lymph node dissection in conjunction with pulmonary metastasectomy from colorectal cancer is associated with improved survival compared to pulmonary metastasectomy only.
- Conditions
- Lung Neoplasms, Neoplasm Metastasis, Colorectal Cancer
- Trial name
- NCT03113318
- Testing
- Total mediastinal lymph node dissection and pulmonary metastasectomy, Only pulmonary metastasectomy
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Colorectal Cancer, Inflammatory Bowel Diseases
Microbiota-anastomotic Leak Among Colorectal Surgery Patients : Pilot Study
The study is based on the hypothesis that patients with postoperative anastomotic leakage have a different bacterial profile contributing to poor tissue healing, and that patients operated for colon cancer presumably have a…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Microbiota, Anastomotic Leak
- Trial name
- NCT03496441
- Testing
- Fecal sample collection for analysis
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colorectal Carcinoma
Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial
This clinical trial compares the impact of the Smart Symptom Tracking ALEX application (app) to standard symptom-tracking practices in tracking and monitoring gastrointestinal (GI) symptoms in young adults.
- Trial name
- NCT07618273
- Testing
- Artificial Intelligence-based Intervention, Best Practice, Communication Intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Colorectal Cancer
¡Salud! Por la Vida (SPLV) A Colorectal Screening Promotion Program
The overall goal of this educational program was to increase colorectal cancer screening (CRCS) in men and women who attend Federally Qualified Health Centers (FQHC) in Puerto Rico.
- Trial name
- SPLV (NCT05502666)
- Testing
- ¡Salud! Por la Vida
- Where
- Puerto Rico
- Volunteers
- 445 people, healthy volunteers welcome
- Sponsor
- University of Puerto Rico
Colorectal Cancer
Colorectal Cancer Screening in Chinese Rural Communities
Colorectal cancer (CRC) is one of the most common malignant neoplasms significantly impacting population health and longevity. With the transformation of lifestyle and dietary patterns among Chinese residents, coupled with an…
- Trial name
- SMART-CRC (NCT07180303)
- Testing
- Remote training courses covering the latest CRC screening guidelines, identification of high-risk individuals and their standard of care, and dietary intervention strategies. Ongoing support services,, Continuation of routine healthcare services without any additional training interventions.
- Where
- China
- Volunteers
- 20,026 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Hepatocellular Carcinoma, Glioblastoma
NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors
The primary objective of this study is to evaluate the safety and clinical activity of NKG2D-based CAR-T cells infusion in the treatment of relapsed/refractory NKG2DL+ solid tumors.
- Conditions
- Hepatocellular Carcinoma, Glioblastoma, Medulloblastoma, Colon Cancer
- Trial name
- NCT04270461
- Testing
- NKG2D-based CAR T-cells
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jiujiang University Affiliated Hospital
Anal Cancer
ASSESSING THE GAY MALE EXPERIENCE WITH ANAL CANCER PREVENTION STRATEGIES
The purpose of this study is to describe current knowledge and opinions about anal cancer screening among men who have sex with men (MSM), as well as their experience receiving guideline-compliant care aimed at anal cancer risk…
- Trial name
- NCT05628194
- Testing
- Observational/Survery
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Colorectal Cancer
A Program for Improved Family Screening for Colorectal Cancer
A first- degree family history of colorectal cancer (CRC) or adenoma before age 65 is associated with a high risk of CRC. For these high-risk subjects, the French 2013 recommendations advise colonoscopy screening, but…
- Trial name
- COLOR3 (NCT03620877)
- Testing
- Personalized intervention
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Colorectal Cancer
Scope Pilot Research Study
Colorectal cancer is a major public health concern in Alberta. Colorectal Cancer is the fourth most common diagnosed cancer and second overall in terms of cancer deaths in Canada.
- Trial name
- SCOPE (NCT00893503)
- Testing
- colonoscopy
- Where
- 2 sites in Canada
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Colonic Carcinoma, Laparoscopic Right Hemicolectomy
Standardizing Right Hemicolectomy for Colon Cancer
A surgical intervention might be highly variable amongst surgeons and centers. This variability has a potential relevance concerning clinical outcomes.
- Conditions
- Colonic Carcinoma, Laparoscopic Right Hemicolectomy, Standardisation, Training
- Trial name
- Right (NCT04889456)
- Testing
- Implementation standardised laparoscopic right hemicolectomy with proctoring, Implementation standardised laparoscopic right hemicolectomy without proctoring
- Where
- Netherlands
- Volunteers
- 930 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Colorectal Cancer
Veteran Primers for CRC Screening
This is a prospective, randomized controlled trial that will evaluate the effectiveness of primer postcards sent two weeks prior to the mailing of a FIT kit in improving adherence to annual CRC screening.
- Trial name
- NCT04923646
- Testing
- Primer
- Where
- United States
- Volunteers
- 2,404 people, healthy volunteers welcome
- Sponsor
- VA Puget Sound Health Care System
Colorectal Cancer
Magnesium Treatment on Vitamin D Metabolism in Participants Completed Personalized Prevention of Colorectal Cancer Trial
One striking observation is that a large portion of the inter-person variation in serum 25-hydroxyvitamin D (25(OH)D) levels is unexplained.
- Trial name
- NCT03265483
- Testing
- Magnesium glycinate
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
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