Clinical trials: Intestine
Reflux Oesophagitis
Effect of Single Doses of YF476 on Stomach Acidity Compared With Ranitidine and Placebo in Fasted and Fed States
The objectives of the study were: To compare a single dose of YF476 at 3 dose levels, placebo and ranitidine with respect to their effects on basal- and food- stimulated gastric pH in healthy volunteers.
- Trial name
- NCT01538797
- Testing
- YF476, Ranitidine
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Hypertension, Essential
Single Dose Bioequivalence Study Comparing Nifedipine/Candesartan FDC (Fixed Dose Combination) With Loose Combination of Nifedipine GITS (Gastro-intestinal Therapeutic System) Plus Candesartan and Single Components Under Fasting Conditions
Randomized, open label, single dose, 4-way crossover study to investigate the bioequivalence of a new fixed dose combination tablet of nifedipine GITS and candesartan with the corresponding loose combination and to compare it…
- Trial name
- NCT01227603
- Testing
- Nifedipine-candesartan FDC (BAY 98-7106), Nifedipine GITS (Adalat LA, BAYA1040), Candesartan (Atacand)
- Where
- Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Bayer
Human Microbiome
Oral Probiotics on the Shift in Gut Microbiome and Skin Carotenoid Levels
The purpose of this study is to determine how probiotics affects circulating carotenoid levels.
- Trial name
- NCT04841694
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Quality of Life, Anal Fistula
Changes in Patients' Quality of Life With Differences in Seton Application
Investigators aim to investigate the changes in patients' quality of life with different type of seton application.
- Trial name
- NCT05348473
- Testing
- Alpha type, Beta type, Comfort type
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ankara University
Anal Cancer
ASSESSING THE GAY MALE EXPERIENCE WITH ANAL CANCER PREVENTION STRATEGIES
The purpose of this study is to describe current knowledge and opinions about anal cancer screening among men who have sex with men (MSM), as well as their experience receiving guideline-compliant care aimed at anal cancer risk…
- Trial name
- NCT05628194
- Testing
- Observational/Survery
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Colon Polyps
Prospective Study of Colonoscopic Resection of Large Polyps and Flat Lesions
With this study, the investigators plan to review the performance of colonoscopic resection of large (> 1 cm) and flat lesions in the colon.
- Trial name
- NCT02332772
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Cancer
A Program for Improved Family Screening for Colorectal Cancer
A first- degree family history of colorectal cancer (CRC) or adenoma before age 65 is associated with a high risk of CRC. For these high-risk subjects, the French 2013 recommendations advise colonoscopy screening, but…
- Trial name
- COLOR3 (NCT03620877)
- Testing
- Personalized intervention
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
IBS - Irritable Bowel Syndrome
The Prevalence of Irritable Bowel Syndrome Using Rome IV Criteria in Medical Student and The Related Factors
A cross-sectional study of 350 medical student Universitas Indonesia from first grade until fifth grade was done during November-December 2016. This study used stratified randomized sampling.
- Trial name
- IBS (NCT03178877)
- Testing
- No intervention
- Where
- Indonesia
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
GERD, Reflux
Role of ARMA in Selective Subset of Refractory GERD Patients.
To study the role of a novel endoscopic treatment technique (ARMA) in GERD patients who doesn't respond to PPI therapy (Proton Pump Inhibitor).
- Conditions
- GERD, Reflux, Reflux Esophagitis
- Trial name
- NCT05899491
- Testing
- ARMA, UGI Endoscopy
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Overweight, Obesity
The Effects of Quinoa and Buckwheat on Weight Management and Gut Microbiome
This study aims to compare the effects of quinoa, buckwheat, rice, and bulgur consumption on dietary intake, anthropometric measurements, glycemic response, lipid profile, inflammatory markers, blood pressure, and intestinal…
- Trial name
- NCT07513610
- Testing
- quinoa, Buckwheat, Rice
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Modulation of the Gut-brain Axis by Cranberries: Impact on University Students' Mental Wellbeing
In this work, the investigators will assess whether cranberry (poly)phenols improve mood disorders including stress, anxiety and depression via the gut-brain axis in university students.
- Trial name
- CM (NCT05260346)
- Testing
- Cranberry juice
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- King's College London
Long COVID
Evaluating the Effects of a Fermented Diet on Microbiome Diversity in Individuals With Long COVID
The purpose of this study is to evaluate the effects of fermented foods on bacterial gut microbiome diversity of long-COVID subjects.
- Trial name
- NCT06560554
- Testing
- Fermented foods, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Crohn's Disease
A Prospective, Placebo Controlled, Double-Blind, Cross-over Study on the Effects of a Probiotic Preparation (VSL#3) on Metabolic Profile, Intestinal Permeability, Microbiota, Cytokines and Chemokines Expression and Other Inflammatory Markers in Pediatric Patients With Crohn's Disease
Background VSL#3 has been reported as an effective adjuvant therapy both in inducing and maintaining remission in pediatric patients affected by Ulcerative Colitis.
- Trial name
- NCT01632462
- Testing
- VSL#3
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federico II University
Colorectal Cancer
Scope Pilot Research Study
Colorectal cancer is a major public health concern in Alberta. Colorectal Cancer is the fourth most common diagnosed cancer and second overall in terms of cancer deaths in Canada.
- Trial name
- SCOPE (NCT00893503)
- Testing
- colonoscopy
- Where
- 2 sites in Canada
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Inflammatory Bowel Disease
Psychobiology in Inflammatory Bowel Disease(IBD)
Patients with ulcerous colitis and Crohn's disease, age 18-60, with a relapse within the last 18 months and an activity index ≥4, with a long time stress level ≥60 on the perceived stress questionnaire (PSQ) were randomized to a…
- Trial name
- INSPIRE (NCT00248742)
- Testing
- Psychological behavioral intervention
- Where
- Norway
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Colonoscopy, Bowel Preparation
Acid-base Balance in Patients Undergoing Colonoscopy
The purpose of this study is to determine whether fluid administration in patients undergoing colonoscopy should affect acid-base disorder in term of the strong ion differences.
- Trial name
- NCT01250886
- Testing
- Lactated Ringer's solution, Normal saline solution, Acetate Ringer's solution
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Crohn Disease, Spondyloarthritis
Identification of Fecal Microbiota Biomarkers of Spondyloarthritis in Patients Suffering From Crohn's Disease.
The MICROSPA project aims to compare gut microbiota, serum cytokines, and PBMC of patients suffering from Crohn's disease (CD) associated or not to spondylarthritis (SpA).
- Trial name
- MICROSPA (NCT03983473)
- Testing
- Microbiota Sequencing
- Where
- 2 sites in France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Short Bowel Syndrome
Mechanisms of Adaptation in Human Short Bowel Syndrome
This is an observational, natural history trial of mechanisms of gut adaptation in adult short bowel syndrome (SBS). Patients with SBS (< 200 cm small bowel ± colon) will be studied initially 2-9 months after the last small bowel…
- Trial name
- NCT00248573
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Emory University
Peptic Ulcer, Dyspepsia
HEP-FYN 12-Years Follow-up
Aims: 1. Evaluate the long-term effect of screening and eradication of Helicobacter Pylori on the prevalence of dyspepsia, and, as secondary outcomes, to assess the effect on dyspepsia related health-care consumption and quality…
- Conditions
- Peptic Ulcer, Dyspepsia, Reflux
- Trial name
- NCT02001727
- Testing
- 13C-Urea breath test for Helicobacter Pylori, Questionaire
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Insomnia, Sleep Disturbance
Exploration of Relationships Between Sleep, Gut Health and Cognition
Our study aims to build on emerging evidence showing relationships between gut health, sleep and brain functions. To achieve this, our study aims to test the feasibility of using non-pharmacological interventions: a…
- Trial name
- NCT05315986
- Testing
- Saffr'Inside; 30mg, Enhanced Sleep Education
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of East Anglia
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