Clinical trials: Intra-Abdominal Hypertension
Intra-Abdominal Hypertension, Respiratory Mechanics
Intra-Abdominal Pressure, Respiratory Mechanics, and Ventilator Liberation After Emergency Major Laparotomy
This prospective observational cohort study aims to investigate the relationship between intra-abdominal pressure (IAP), respiratory system mechanics, and successful liberation from invasive mechanical ventilation in adult…
- Conditions
- Intra-Abdominal Hypertension, Respiratory Mechanics, Mechanical Ventilation
- Trial name
- IAP-VENT (NCT07889609)
- Testing
- Serial Intra-Abdominal Pressure and Respiratory Mechanics Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Intra-Abdominal Hypertension, Critical Illness
Intra-Abdominal Pressure Changes During Continuous Renal Replacement Therapy in Critically Ill Patients
This prospective observational study will evaluate changes in intra-abdominal pressure in critically ill adult patients receiving continuous renal replacement therapy in the intensive care unit.
- Conditions
- Intra-Abdominal Hypertension, Critical Illness, Continuous Renal Replacement Therapy
- Trial name
- NCT07823387
- Testing
- Intravesical Intra-abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Intra-abdominal Hypertension, Acute Respiratory Distress Syndrome (ARDS)
End-expiratory Transpulmonary Pressure-guided vs Electrical Impedance Tomography-guided PEEP Titration Methods in Patients With Intra-abdominal Hypertension Combined With Acute Respiratory Distress Syndrome: a Randomized Crossover Controlled Study
This study aims to adopt a randomized crossover design to compare the effects of end-expiratory transpulmonary pressure-guided PEEP titration and EIT-guided PEEP titration on local lung ventilation, shunt, dead space, and…
- Trial name
- NCT06697717
- Testing
- Transpulmonary Pressure-Guided PEEP Titration in IAH and ARDS Patients, EIT-Guided PEEP Titration in IAH and ARDS Patients
- Where
- China
- Volunteers
- 15 people
- Sponsor
- XiaoJing Zou,MD
Intra-Abdominal Hypertension, Postoperative Complications
The Impact of Intra-Abdominal Pressure on Mortality and Morbidity in Patients Undergoing Open-Heart Surgery
This prospective observational study evaluated whether increased intra-abdominal pressure, meaning increased pressure inside the abdomen, is associated with postoperative complications and mortality in adults undergoing elective…
- Trial name
- NCT07752082
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Intraabdominal Hypertension, Abdominal Compartment Syndrome
Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants
The goal of this clinical trial is to learn more about intestinal regional oxygen saturation measurements made with near-infrared spectroscopy and bladder pressure measurements in infants without risk of intraabdominal…
- Trial name
- BPvsNIRS (NCT05971264)
- Testing
- Near infrared-spectroscopy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Lumbar Spinal Stenosis, Lumbar Degenerative Disease
Effect of Obesity Phenotype on Intraabdominal Pressure and Bleeding in Major Lumbar Spinal Surgery
Obesity is prevalent among patients with lumbar degenerative disease and is a known risk factor for perioperative complications in spinal surgery.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Degenerative Disease, Obesity, Intraabdominal Hypertension
- Trial name
- OBESPINE (NCT07688265)
- Testing
- Intraabdominal Pressure Measurement via Urinary Bladder Catheter, Total Intravenous Anesthesia (TIVA)
- Volunteers
- 90 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Abdominal Hypertension, Abdominal Compartment Syndrome
Updated Abdominal Compartment Society Consensus Definitions
An international team of experts is working on a project called updated WSACS consensus definitions. The goals of this study are to: 1. To generate expert consensus on the definitions and classification of IAH and ACS. 2.
- Trial name
- WSACS (NCT07563842)
- Testing
- Delphi study
- Where
- Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Intracranial Pressure Increase, Abdominal Compartment Syndrome
Vasopressin in Intraabdominal Pressure Elevation
The aim of this study is to investigate any direct correlation between increased intrathoracic pressure, intraabdominal pressure and intracranial pressure, following a controlled elevation in intraabdominal pressure and…
- Trial name
- NCT03707054
- Testing
- Study Arm
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Intra-Abdominal Hypertension, Inguinal Hernia
Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output
This study serves as a pilot study with the intention to to measure intraabdominal pressure, lactic acid, and urine output in obese individuals undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT05070572
- Testing
- Accuryn Monitoring System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Antonios Likourezos
Intra-Abdominal Hypertension
Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter
The purpose of this study is to investigate the intra-abdominal pressure utilizing the Accuryn monitoring system during pulsed field ablation procedures in the electrophysiology lab compared to the type of anesthetic utilized.
- Trial name
- IAP (NCT06876896)
- Testing
- Accuryn Foley catheter device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Intra Abdominal Pressure, Intra-Abdominal Hypertension
Intra-gastrointestinal Monitoring Device (PressureDOT®) and Centurion IAP Monitoring Device Comparison Study: Pivotal Study of Safety and Performance.
The proposed clinical study protocol is intended to establish the safety, utility, and reliability of using a pressure-sensing capsule present in a patient's gastrointestinal tract for monitoring intraabdominal pressure (IAP).
- Trial name
- NCT07400666
- Testing
- digital capsule
- Volunteers
- 26 people
- Sponsor
- Dotspace Inc.
Abdominal Compartment Syndrome
Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication
An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti…
- Trial name
- NCT06291389
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Acute Heart Failure, Congestive Heart Failure
The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure
Systemic venous congestion is the primary therapeutic target of intravenous loop diuretics in patients admitted for acute heart failure (AHF).
- Conditions
- Acute Heart Failure, Congestive Heart Failure, Intraabdominal Hypertension, Cardio-Renal Syndrome
- Trial name
- ABDOPOCUS-HF (NCT07008365)
- Testing
- Furosemide 20 Milligrams
- Where
- 2 sites in Spain
- Volunteers
- 168 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Acute Respiratory Distress Syndrome, Acute Kidney Injury
Prone Position and Renal Resistive Index
Patients suffering from Acute Respiratory Distress Syndrome (ARDS) with a prone position (PP) indication will benefit from measurements of renal resistive index, intra-abdominal pressure (IAP), urinary oxygen tension (uPO2) and…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Kidney Injury, Prone Position, Intra-Abdominal Hypertension
- Trial name
- PRO-KIDNEY (NCT04286490)
- Testing
- Prone position
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Intraabdominal Hypertension, Multi-Organ Disorder
Correlation Between Intra-abdominal Pressure, Biomarkers of Bacterial Translocation and Intestinal Wall Damage
Main scientific hypotheses of the project: 1. The level of intestinal microflora translocation markers and biomarkers of intestinal wall damage the in the blood serum correlates with the level of intra-abdominal pressure…
- Conditions
- Intraabdominal Hypertension, Multi-Organ Disorder, Translocation Syndrome
- Trial name
- NCT06221293
- Testing
- immunoenzyme analysis
- Where
- 5 sites in Kazakhstan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Intra-Abdominal Hypertension
First-In-Human Study of PDT to Detect IAH
PDT is a continuous pressure monitoring for Intra-Abdominal hypertension (IAH) designed to be less invasive than pan-endoscopic evaluation, more tolerable than abdominal tapping, and more effective than intravesical pressure…
- Trial name
- NCT06333366
- Testing
- Intra-gastrointestinal monitoring device (PDT)
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Intra-Abdominal Hypertension, Venous Congestion
Correlation of Ultrasonography Indices of Venous Congestion With Intra-abdominal Pressure in ICU Patients.
The goal of this prospective observational study is to examine the potential association between intra-abdominal pressure and venous congestion as assessed by abdominal ultrasound, in critically ill patients in the Intensive Care…
- Trial name
- NCT06160856
- Testing
- Abdominal ultrasound
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens