Clinical trials: Intra-Articular Fractures
Distal Femur Fracture, Tibial Plateau Fracture
Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
The overall objective of this study is to compare outcomes following early advanced weight bearing (EAWB) using the AlterG antigravity treadmill versus standard of care physical therapy for adult patients with lower extremity…
- Conditions
- Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
- Trial name
- AlterG (NCT03562364)
- Testing
- AlterG anti-gravity treadmill
- Where
- 10 sites in United States
- Volunteers
- 81 people
- Sponsor
- Major Extremity Trauma Research Consortium
Distal Radius Fracture, Osteoarthritis
Intra-Articular Dexamethasone to Prevent Post-Traumatic Osteoarthritis: A Pilot Study
The primary aim of the study is to see if a single wrist injection (intra-articular) of dexamethasone at the time of treatment will reduce the incidence of early-onset of post traumatic osteoarthritis.
- Trial name
- NCT02318433
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Mayo Clinic
Femoral Neck Fractures
Topical (Intra-Articular) Tranexamic Acid and Transfusion Rates Following Hip Hemiarthroplasty
This study is a double-blinded placebo-controlled clinical trial evaluating the efficacy of 1 gram of topically applied tranexamic acid vs. saline placebo for the reduction of transfusion following hip hemiarthroplasty surgery.
- Trial name
- NCT02664909
- Testing
- Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- UConn Health
Ankle Fractures, Intra-Articular Fractures
Prevention of Posttraumatic Osteoarthritis After Acute Intraarticular Fractures
Intra-articular fracture is a very common fracture. The only method to treat these fractures is surgery with plate and screws followed by rehabilitation.
- Conditions
- Ankle Fractures, Intra-Articular Fractures, Osteoarthritis
- Trial name
- NCT03769909
- Where
- Denmark
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Calcaneus Fractures
Comparative Study Between Internal Fixtion And Primary Subtalar Arthrodesis In Comminuted Intra-Articular Calcaneal Fracture
This study is to compare clinical outcome of Sanders type III or IV intra-articular calcaneal fracture treated with open reduction and internal fixation (ORIF) versus ORIF and primary subtalar arthrodesis (PSTA).
- Trial name
- NCT07423507
- Testing
- Primary Subtalar Arthrodesis, Open reduction and internal fixation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ahmed Gamal Ibrahim Saleh
Articular Fracture
Volar Locking Plate Comparison With External Fixator
Local data has shown conflicting results regarding the outcomes of volar locking plates versus external fixators in distal intra-articular radius fractures.
- Trial name
- NCT07576075
- Testing
- Volar locking plates, External Fixator
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Muhammad Aamir Latif
Radius Fracture Distal
A Study Examining The Effect Of Wrist Joint Haematoma Washout As An Adjunct Procedure To Plating Of The Distal Radius In Fractures Of The Distal Radius Involving The Wrist Joint
Intra-articular fractures of the distal radius are common in urban populations and result in significant morbidity in terms of time away from work.
- Trial name
- JWDRF (NCT04135768)
- Testing
- Wrist joint haematoma washout, Volar locking plate insertion of the distal radius
- Where
- Malaysia
- Sponsor
- University of Malaya
Radius Fractures
External Fixation Vs. Volar Plate for Distal Radius Fractures: Functional Outcomes
The goal of this prospective comparative clinical trial is to evaluate the effectiveness of external fixation versus volar locking plates in the management of unstable intra-articular distal radius fractures in adults over 18…
- Trial name
- NCT06738693
- Testing
- External Fixation, Open Reduction and Internal Fixation (ORIF) with Volar Locking Plate
- Where
- Nepal
- Volunteers
- 42 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Ankle Fractures
AORIF Complex Ankle Fractures
The aim of this study is to evaluate the intraarticular lesions, to identify fractures specifically at risk for these, and to assess the results following arthroscopically assisted open reduction and internal fixation of complex…
- Trial name
- NCT04033848
- Testing
- Arthroscopic assisted ankle fracture treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Fractures, Bone
Comparing Efficacy of Bone Marrow Aspirate Concentrate (BMAC) Combined With Allograft in Treatment of Calcaneus Fractures
The purpose of this study is to evaluate the efficacy of BMAC when used in conjunction with viable allograft bone for treating displaced intra-articular calcaneal fractures, in terms of rate of allograft incorporation into the…
- Trial name
- BMAC (NCT05017961)
- Testing
- Autograft, Allograft only, Allograft combined with BMAC
- Sponsor
- University of Alabama at Birmingham
Elbow Joint Destruction, Post-traumatic Lesions
Clinical Outcomes Study of the Nexel Total Elbow
The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
- Conditions
- Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis
- Trial name
- NCT02469662
- Testing
- Nexel Total Elbow
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 134 people
- Sponsor
- Zimmer Biomet
Distal Radius Fracture
Paper- vs Digital Application-based Exercises to Support Rehabilitation After Osteosynthesis of Distal Radius Fracture
The aim of this study is to evaluate the difference between the use of paper- versus application-based (smartphone application) exercises in the rehabilitation of intra-articular fractures of the distal radius at the Cantonal…
- Trial name
- NCT06005857
- Testing
- Standard hand therapy + home digital application-based exercises, standard hand therapy + home paper-based exercises
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Hôpital Fribourgeois
Intraarticular Fracture and Post-traumatic Osteoarthritis
Inflammatory Response Following Intraarticular Fracture
The purpose of the study is to investigate a relationship between the inflammatory response following intraarticular fracture and post-traumatic osteoarthritis.
- Trial name
- PTOA (NCT01514643)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Distal Radius Fracture, 3D Printing
Effects of Preoperative 3D Printing of Distal Intra-articular Radius Fractures on Quality of Fracture Reduction
The investigators aim to evaluate the effect of a preoperative 3D printed Model (3PAS) of distal intraarticular radius fractures on quality of fracture reduction.
- Trial name
- 3PAS (NCT05739240)
- Testing
- Osteosynthesis
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vilijam Zdravkovic
Pilon Fracture
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
High energy intra-articular fractures of the distal tibia, or Pilon fracture, is a devastating injury with multiple short and long term complications.
- Trial name
- NCT03652753
- Testing
- N-acetylcysteine, Saline
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Missouri-Columbia
Tibial Fractures
Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques
Comminuted intra-articular distal tibia fractures (OTA 43-C) typically are the result of high-energy trauma such as motor vehicle collisions or fall from a height.
- Trial name
- CIDUCT (NCT02845245)
- Testing
- 3D printed plastic model prototype, 3D CT scan, Plain film radiographs
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Inova Health Care Services
Wrist Fractures, Intraarticular Injection
Efficacy of Intra-Articular Corticosteroid Injections on Clinical Outcomes in Patients With Operative Distal Radius Fractures
The randomized controlled study which compare clinical outcomes (functional score) in patients with distal radius fractures who underwent open reduction with internal fixation and received intra-articular steroid injections to…
- Trial name
- NCT06407180
- Testing
- Triamcinolone Acetonide, Normal saline
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Teeradon Waewworawit
Intraarticular Fracture, Extraarticular Fracture
Prospective Post-market Clinical Follow-up Study of the HBS 2 Resorb Mg in Patients With Intra- and Extraarticular Fractures, Pseudarthroses and Arthrodesis of Small Bones and Bone Fragments.
This study is a multi-centre, prospective, clinical observational study to evaluate the CE-marked HBS 2 Resorb Mg screws under routine conditions. The device will be used according to its intended use.
- Conditions
- Intraarticular Fracture, Extraarticular Fracture, Pseudarthrosis, Arthrosis
- Trial name
- NCT05483387
- Testing
- Treatment with HBS 2 Resorb Mg
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KLS Martin
Radius Fracture
Magnesium Sulfate and Bupivacaine for Rehabilitation After Distal Radius Fractures
This study evaluates the effect of 10% magnesium sulfate in the rehabilitation of the wrist mobility in patients with distal radius fracture treated with percutaneous pinning and plaster
- Trial name
- NCT02514343
- Testing
- Magnesium Sulfate, Bupivacaine
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Elbow Fracture
Steroid Administration for Articular Fractures of the Elbow (SAFE Trial)
The primary purpose of this study is to determine if perioperative glucocorticoid administration (IV intra-operative followed by a post-operative oral taper course) improves post-operative range of motion in a patient population…
- Trial name
- SAFE (NCT04738318)
- Testing
- Glucocorticoids, Saline
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center