Clinical trials: Intracranial Venous Pressures
Idiopathic Intracranial Hypertension
The Effects of MAP and EtCO2 on Venous Sinus Pressures
The purpose of this study is to further elaborate the role of both arterial blood pressure and end-tidal carbon dioxide concentration on measured venous pressures.
- Trial name
- NCT03867461
- Testing
- Venous Sinus Stenting, Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range), Adjustment to Mean Arterial Pressure (100-110 mmHg range)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation
Intracranial Pressure and a Potential Vicious Circle of Atrial Fibrillation in HFpEF
This study was designed to investigate predictors of atrial fibrillation (AF) in patients with heart failure with preserved ejection fraction (HFpEF), with a particular focus on the potential relationship between venous…
- Conditions
- Heart Failure With Preserved Ejection Fraction (HFpEF), Atrial Fibrillation, Optic Nerve Sheath Diameter, Intracranial Pressure
- Trial name
- heart failure (NCT07521293)
- Testing
- Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
End- Stage Renal Disease Patients
The Hemodynamic Effects During Sustained Low-efficiency Dialysis Versus Continuous Veno-venous Hemofiltration for Patients With Intracranial Hypertension in a Cross Over Study
Hemodynamic instability occurs frequently during dialysis treatment and still remains as significant cause of patient mobility and mortality.
- Trial name
- NSARF (NCT01781585)
- Testing
- hemodialysis
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Indication for CSF Dynamic Testing, Indication for CSF Infusion Test
Investigation of a New Window Into Intracranial Pressure: Venous Occlusion Pressure of the Isolated Periorbital Vein
Elevated intracranial pressure (ICP) occurs when pressure inside the skull rises above normal levels, potentially leading to brain damage or herniation.
- Trial name
- VOPxICP (NCT07053631)
- Testing
- venous occlusion pressure Measurement
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- University of Freiburg
Acute Brain Injury, Traumatic Brain Injury
Effect of Central Venous Catheterization on Brain Pressure in Acute Brain Injury Patients
Acute brain injury (ABI) is a serious condition that can cause a dangerous increase in pressure inside the skull (called intracranial pressure, or ICP), which can harm the brain.
- Conditions
- Acute Brain Injury, Traumatic Brain Injury, Intracerebral Hemorrhage, Aneurysmal Subarachnoid Hemorrhage (aSAH)
- Trial name
- CVC-ICP (NCT07704528)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Pressure, Critical Care
JUgular Gating for Upright Level Adjustment and Targeted Enhancement of Cerebral Perfusion
Investigators aim to demonstrate that the evolution of intracranial pressure (ICP) is nonlinear and may be influenced by jugular vein collapse.
- Trial name
- JUGULATE (NCT07665606)
- Testing
- Ultrasound assessment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bordeaux
Cerebral Venous Sinus Thrombosis, CSF Pressure Increased
Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales
This is a single-center, retrospective, open-label study. This study is planned to investigate the accuracy of mRS and NIHSS, comparing with the accuracy of CSF pressure and papilledema grade in assessing cerebral venous sinus…
- Conditions
- Cerebral Venous Sinus Thrombosis, CSF Pressure Increased, Papilledema
- Trial name
- NCT03273179
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Capital Medical University
Elevated Intracranial Pressure (ICP)
Optic Nerve Sheath Diameter (ONSD) With the Raised PCO2 and Internal Jugular Venous Occlusion
Monitoring the ICP is the most important aspect of the management of these patients. Recently, transorbital ultrasonography has gained popularity as a noninvasive bedside exam that has been shown to be useful in the diagnosis of…
- Trial name
- NCT02361658
- Testing
- Ultrasonographic of the optic nerve sheath diameter, RespirAct™, Neck collar
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lashmi Venkatraghavan
Pituitary Adenoma
Semi-sitting Versus Supine Position in Endoscopic Skull Base Surgery
This study is to prospectively compare the standard supine (control group) and the semi-sitting position (head elevation of 30°; intervention group) in endoscopic endonasal pituitary surgery.
- Trial name
- PosESS (NCT04584866)
- Testing
- Endonasal endoscopic pituitary surgery in semi-sitting position, Endonasal endoscopic pituitary surgery in supine position
- Where
- Switzerland
- Volunteers
- 54 people
- Sponsor
- University Hospital, Basel, Switzerland
Intracranial Stenosis, Venous Sinus Stenosis
This Prospective Observational Study Aims to Evaluate the Capability of Ultra-high-resolution Photon-counting CT Angiography (UHR PCD-CTA) for Noninvasive Evaluation of Intracranial Venous Sinus Stents. The Study Will Compare Image Quality, Stent Visualization, Metal-related Artifacts, and Diagnosti
This prospective observational study aims to evaluate the effectiveness of ultra-high-resolution photon-counting CT angiography (UHR PCD-CTA) for noninvasive assessment of intracranial venous sinus stents.
- Conditions
- Intracranial Stenosis, Venous Sinus Stenosis, Stent Implantation, Intracranial Venous Pressures
- Trial name
- NCT07762677
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xin Lou
Intracranial Venous Pressures
Prospective Measurement of Normal Venous Sinus Pressures
The purpose of this research is to document normal intracranial venous sinus pressures. Participants who need to have a cerebral angiogram to evaluate a medical problem not related to Idiopathic Intracranial Hypertension (IIH)…
- Trial name
- NCT03948971
- Testing
- Venogram
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Intracranial Pressure Measurement, Measurement of Optic Nerve Sheath Diameter
IJV Catheterization and Intracranial Pressure Via ONSD
The aim of this study is to evaluate the effect of internal jugular vein catheterization on intracranial pressure in intubated patients in the intensive care unit using optic nerve sheath diameter
- Trial name
- NCT07465419
- Testing
- Internal jugular vein catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Cumhuriyet University
Intracranial Pressure
Validation of Non-Invasive Intracranial Pressure Estimation Using CPMX3 in the Periorbital Vein: A Feasibility Study in Pediatric Patients
Intracranial pressure (ICP) monitoring is indicated in a wide range of neurological diseases. The combination of a linear ultrasound array with an integrated pressure sensor into a single handheld probe (ICP Probe) enables the…
- Trial name
- VENUS-ICPxP (NCT07550361)
- Testing
- CPMX3 measurement
- Where
- United States
- Sponsor
- Compremium AG
Brain Tumor Adult, Pulse Pressure Variation
Pulse Pressure Variation vs. Central Venous Pressure for Fluid Management in Intracranial Tumor Surgery
This study investigates the efficacy of pulse pressure variation (PPV) compared to central venous pressure (CVP) in guiding fluid management during intracranial tumor surgeries.
- Conditions
- Brain Tumor Adult, Pulse Pressure Variation, Central Venous Pressure, Fluid Management
- Trial name
- PPV-CVP-FLUID (NCT06776666)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Pamukkale University
Intracranial Pressure Increase
Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
This study will test the use of video ophthalmoscope to provide information about intracranial pressure without the use of invasive methods, anesthesia or contact with the eye.
- Trial name
- ICP Waveform (NCT04046523)
- Testing
- Video ophthalmoscope
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Head Injury
Effects of Head Elevation on Intracranial Pressure in Children
Head injury is the most common cause of mortality and acquired disability in childhood. It is common to elevate the head of patients at risk for increased intracranial pressure, although it is not clear if it is always…
- Trial name
- NCT00636376
- Testing
- Place HOB in alternate positions from 0-50 degrees.
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Children's Hospital of Philadelphia
IIH - Idiopathic Intracranial Hypertension
IIH Intervention: A Clinical Trial Comparing 2 Treatments (Shunts and Stents) Evaluation Of Clinical Effectiveness And Cost Effectiveness
Background and study aims Idiopathic intracranial hypertension (IIH) is a neurological condition characterised by increased pressure inside the skull, called intracranial pressure (ICP).
- Trial name
- Intervention (NCT07440277)
- Testing
- CSF shunt, DVSS
- Where
- 15 sites in United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Birmingham
Intracranial Pressure, Ultrasonography
Effect of Internal Jugular Vein Catheterization on Intracranial Pressure and Intracranial Blood Flow
This prospective observational study aims to evaluate the effect of internal jugular vein catheterization on intracranial pressure using optic nerve sheath diameter (ONSD) measurements and carotid artery Doppler ultrasonography…
- Trial name
- NCT07540481
- Testing
- Internal Jugular Vein Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Brachial Plexus Block, Intracranial Pressure Increase
The Effect of Interscalene Block on Intracranial Pressure
The study aims to show the effects of interscalene brachial plexus (ISBP) block on intracranial pressure by measuring optic nerve sheath diameter (ONSD) and internal vein collapsibility index (IJV-CI).
- Trial name
- NCT05434975
- Testing
- Interscalene brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cumhuriyet University
Cerebral Vein Thrombosis
Rivaroxaban vs. Warfarin in CVT Treatment
Cerebral venous thrombosis (CVT) is an uncommon venous-type of stroke tends to affect younger patients with somewhat different risk factors and much better outcome compared to arterial strokes.
- Trial name
- RWCVT (NCT04569279)
- Testing
- Rivaroxaban, Warfarin
- Where
- Syria
- Volunteers
- 71 people
- Sponsor
- Damascus University