Clinical trials: Intramedullary Nail, open to volunteers
Tibial Fractures, Fracture Infection
Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study
Primary objective of this study is to compare fracture related infection (FRI) rates of ZNN Bactiguard Tibia to conventional uncoated titanium-alloy nails 12 months after tibia fracture fixation.
- Trial name
- NCT05022485
- Testing
- ZNN Bactiguard tibia
- Where
- 16 sites in Austria, France and 6 more
- Volunteers
- 500 people
- Sponsor
- Zimmer Biomet
Femoral Fracture
ZNN Bactiguard Retrograde Femoral Nails PMCF Study
Post-market clinical follow-up (PMCF) study to confirm the safety, performance, and clinical benefits of the intra-medullary retrograde femoral nail Zimmer Natural Nail (ZNN) Bactiguard (implants and instrumentation) when used…
- Trial name
- NCT05276674
- Testing
- ZNN Bactiguard Retrograde Femoral Nail
- Where
- 4 sites in Spain, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Femur Fracture, Osteotomy
ZNN Bactiguard Antegrade Femoral Nails PMCF Study
This is a multicenter, prospective, Post-market Clinical Follow-up (PMCF) Study on the ZNN Bactiguard Antegrade Femoral Nails. The objective of this study is to collect data confirming the safety, performance, and clinical…
- Trial name
- NCT05339360
- Testing
- Femoral fixation with intramedullary nails
- Where
- 2 sites in Spain, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Zimmer Biomet
Bone Metastases
Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur
The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega.
- Trial name
- NCT06918860
- Testing
- Analysis
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Costantino Errani
Bone Metastases, Pathological Fracture
Short Versus Long Intramedullary Nails in the Treatment of Proximal Femur Metastasis.
The goal of this interventional randomized controlled trial is to compare the clinical outcomes in treating extremities pathological fractures (fractures of limbs caused by metastatic tumors) or impending pathological fractures…
- Conditions
- Bone Metastases, Pathological Fracture, Pathological Fracture, Left Femur, Pathological Fracture, Right Femur
- Trial name
- NCT05969470
- Testing
- Internal fixation with short intramedullary nails, Internal fixation with long intramedullary nails
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Bone Metastases, Lymphoma
Post-Op Pain Control for Prophylactic Intramedullary Nailing.
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing…
- Conditions
- Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use
- Trial name
- NCT03823534
- Testing
- Ketorolac, Normal saline, Acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Tibial Fracture
Tibial IMN Vs. Tibial Micromotion IMN
Our null hypothesis is that micromotion tibial intramedullary fixation (IMFN) does not impact union or complication rates when compared to standard of care treatment with non-micromotion tibial nail fixation.
- Trial name
- NCT06976801
- Testing
- Intramedullary tibial Nail, Intermedullary nail
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- University of Chicago
Tibia Fractures
Comparison of Knee Muscle Function After Suprapatellar and Infrapatellar Tibial Nailing in Patients With Tibial Shaft Fractures
The goal of this observational study is to compare the recovery of knee muscle strength and function in adults aged 18 to 65 years with a fracture in the middle part of the shinbone.
- Trial name
- NCT07862907
- Testing
- Infrapatellar Tibial Intramedullary Nailing, Suprapatellar Tibial Intramedullary Nailing
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Pathologic Fracture, Bone Metastases
Metastatic Pathologic Fractures, Short Term Results
This is a single center prospective study to compare the short term results of prosthesis, nail and plate-screw surgeries for metastatic pathologic fractures.
- Conditions
- Pathologic Fracture, Bone Metastases, Metastatic Cancer
- Trial name
- NCT05825456
- Testing
- endoprosthetic reconstruction, Intramedullary nailing, Open reduction internal fixation with plate and screws
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara University
Forearm Injuries, Radius Fractures
Time to Healing in Displaced Pediatric Diaphyseal Forearm Fractures Treated With Bioabsorbable Compared to Titanium Intramedullary Nails
This study looks at children with forearm fractures that need surgery. The standard treatment uses titanium nails, which usually need to be removed in a second operation later.
- Conditions
- Forearm Injuries, Radius Fractures, Ulna Fractures, Fractures, Bone
- Trial name
- FOREST (NCT07536581)
- Testing
- Bioabsorbable intramedullary nail, Titanium elastic intramedullary nail
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Children's Fractures Interest Group, Denmark
Shaft Femure Fracture in Adolescents
Fixation of Shaft Femure Fracrture by Ender Versus Plate
The aim of this study is to compare the functional outcomes, fracture healing time, rate of complications, and long-term growth outcomes between intramedullary nail and plating in adolescent.
- Trial name
- NCT07067333
- Testing
- intramedullary nails for group A, plate for group B
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Tibial Shaft Fracture, Intramedullary Nail
RCT - Suprapatellar Approach Versus Lateral Parapatellar Approach in Tibial Shaft Fracture
This study aims to compare 2 surgical techniques for tibial shaft nailing (suprapatellar approach vs extra-articular lateral parapatellar approach). following peri-operative and postoperative outcomes
- Trial name
- ELPP (NCT07657559)
- Testing
- suprapatellar approach, extra-articular lateral parapatellar approach
- Volunteers
- 40 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Leg Length Inequality
Study to Assess the Pain, Satisfaction, and Quality of Life of Patients With FITBONE® Lengthening Nail
This study is a prospective observational non-interventional multi-centre cohort study of patients, 12 years or older, initiating a lower limb lengthening procedure with FITBONE and who have a length discrepancy of 30mm or more…
- Trial name
- FitForFrance (NCT06156384)
- Testing
- FITBONE® Lengthening Nail
- Where
- 6 sites in France, Reunion
- Volunteers
- 45 people
- Sponsor
- Orthofix s.r.l.
Tibial Fracture, Femoral Fracture
Magnesium-Titanium Hybrid Intramedullary Nail System For Long Bone Fractures
This is a prospective, multicenter, randomized, controlled, non-inferiority clinical trial designed to evaluate the safety and effectiveness of the magnesium-titanium hybrid intramedullary nail system compared with the marketed…
- Conditions
- Tibial Fracture, Femoral Fracture, Humeral Fracture
- Trial name
- NCT07569575
- Testing
- Magnesium-Titanium Hybrid Intramedullary Nail System, Commercially Locked Metallic Intramedullary Nail
- Where
- 5 sites in China
- Volunteers
- 160 people
- Sponsor
- HuaMg Perfection Med Tech (Suzhou) Co., Ltd.
Tibia Fracture
Limb Injuries and Post Injury Rehabilitation Trials - Tibial Shaft Fracture
Aim of our study is to compare immediate full weight-bearing and partial weight-bearing for 6 weeks after a tibial shaft fracture treated with intramedullary nailing.
- Trial name
- LIMPER-TSF (NCT05151926)
- Testing
- Full weight-bearing, Partial weight-bearing, Intramedullary nailing
- Where
- 3 sites in Finland
- Volunteers
- 240 people
- Sponsor
- Tampere University Hospital
Distal Ulna Fracture
Evaluation of Dual Fixation of Distal Ulna Fractures by Flexible Intramedullary Nail and Mini Locked Plate 2.7 mm.
Although isolated fixation methods, such as intramedullary nails or plate fixation, are commonly employed, certain fracture patterns-particularly comminuted, osteoporotic, or unstable fractures- represent a challenge to achieve…
- Trial name
- NCT07440251
- Testing
- Dual fixation of distal ulna fractures by flexible intramedullary nail and mini locked plate 2.7 mm
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Sohag University
Hip Injuries and Disorders, Hip Fractures
Intramedullary Nail Versus Hip Arthroplasty in Unstable Trochanteric Hip Fractures
A hip fracture is a large burden to the patient with increased mortality, pain and increased need for daily assistance. Trochanteric fractures of the femur (FTF) represents about 35% of the hip fractures.
- Trial name
- TUFHIPRCT (NCT04868305)
- Testing
- Intramedullary nail, Hip arthroplasty
- Where
- Norway
- Volunteers
- 170 people
- Sponsor
- Helse Stavanger HF