Clinical trials: Intraocular Lens
Intraocular Lens
Long-term Comparative Analysis of Visual Outcomes With 3 Intraocular Lenses: Monofocal, Trifocal and Accommodating
To compare visual outcomes, contrast sensitivity, glare occurrence, incidence of posterior capsule opacification (PCO) and subjective satisfaction in patients implanted with trifocal, accommodating and monofocal lens in long term…
- Trial name
- NCT05041881
- Testing
- Trifocal lens AT LISA TRI, Zeiss, Accommodating Tetraflex HD lens, Lenstec inc., Monofocal lens, Softec HD
- Where
- 2 sites in Czechia, Slovakia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Cataract
Comparison of Functional Vision Provided by AMO Tecnis Z9000 and Alcon SA60AT Acrysof
This study is to compare intraindividually the functional vision provided by two different posterior chamber intraocular lenses: AMO Tecnis Z9000 and Alcon SA60AT Acrysoft.
- Trial name
- NCT00459303
- Testing
- aspherical intraocular lens, spherical intraocular lens
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cataract, Lens Opacity
Comparison of Visual Outcomes After Implantation of the POD AY GF F (PhysIOL) and the POD AY 26P F (PhysIOL)
The study is a prospective randomised controlled study. The patients get monolateral IOL implantation of POD F GF and POD F in the contralateral eye. Both IOLs are trifocal IOLs consisting of the same optical design.
- Trial name
- NCT02981186
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Comparison of Visual Outcomes After Implantation of the POD FT and the POD F
There is no difference of the photic phenomena in the two groups. The study will be a prospective non-randomised controlled study. The target is then to determine the equivalence in the glare.
- Trial name
- PoyPODF/FT (NCT04943809)
- Testing
- POD 26P AY FT, POD 26P AY F
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Dry Eye Disease (DED), Cataract
Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.
This study looks at how dry eye disease can affect important eye measurements needed before cataract surgery. These measurements guide us in choosing the right artificial lens to implant, which is essential for achieving clear…
- Trial name
- NCT06989827
- Testing
- Preservative free artificial tear
- Where
- Croatia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Sestre Milosrdnice
To Collect Information About Visual Outcomes and Participant Satisfaction
Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)
The study is being conducted to collect information about visual outcomes and participant satisfaction with the Tecnis One-Piece Multifocal (MF) Intraocular Lenses (IOLs) compared with participants previously implanted with…
- Trial name
- NCT01191229
- Testing
- Tecnis one-piece MF IOL, Crystalens AO
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Myopia, Hyperopia
A Clinical Evaluation of a Phakic Intraocular Lens
The objective of this study is to evaluate the clinical performance of the STAAR EVO+ Visian™ Implantable Collamer® Lens with Aspheric (EDOF) Optic as refractive elements to correct or reduce myopia or hyperopia with presbyopia…
- Conditions
- Myopia, Hyperopia, Astigmatism, Presbyopia
- Trial name
- NCT07291739
- Testing
- Implantable Collamer Lens (ICL)
- Where
- Philippines
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Staar Surgical Company
Cataract, Presbyopia
A Clinical Evaluation of the LensGen Intraocular Lens
A multi-center, open-label, non-comparative clinical trial to assess the safety and efficacy of the LensGen IOL (Juvene IOL) for the treatment of aphakia and presbyopia after removal of the natural crystalline lens due to…
- Trial name
- Grail (NCT05364658)
- Testing
- Juvene IOL
- Where
- 2 sites in Mexico
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Cataract
Visual Performance With a Trifocal Intraocular Lens
The purpose of this study is to evaluate the visual performance of a trifocal intraocular lens at distance, near and intermediate viewing, by way of visual acuity measurement, contrast sensitivity.
- Trial name
- NCT01605058
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BMI Southend Hospital
Corneal Endothelial Cell Loss, Secondary Intraocular Lens
Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes
This is a prospective comparative non-randomized cohort study to understand the long-term vision outcomes, safety, and stability of anterior chamber intraocular lenses (AC IOLs) vs. scleral-fixated intraocular lenses (SF IOLs).
- Trial name
- NCT04072978
- Testing
- Intraocular lens implantation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Cataract, Lens Opacities
A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses
This is a prospective randomised open-label study with the aim to compare the visual performance of the trifocal FineVision® IOL versus the extended range of vision Symfony® IOL after phaco-emulsification cataract surgery.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03974451
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Visual Acuity
To Evaluate the Visual Performance After Bilateral Implantation of Multifocal Intraocular Lenses
To evaluate the visual performance after bilateral implantation of multifocal intraocular lenses.
- Trial name
- NCT03223857
- Testing
- Femtosecond-laser-assisted lens exchange
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract
Clinical Investigation of the Next-Generation Intraocular Lenses
This study is a 6-month, prospective, multicenter, subject/evaluator-masked, bilateral, randomized clinical investigation of the TECNIS Next-Generation Model ZFR00 and Model ZYR00 IOLs versus the TECNIS Multifocal Model ZLB00…
- Trial name
- NCT03372434
- Testing
- Investigational Intraocular Lens Device #1: Model ZFR00, Investigational Intraocular Lens Device #1: Model ZYR00, TECNIS Multifocal Intraocular Lens: Model ZLB00
- Where
- 12 sites in United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Lens Opacities
Multicentric Clinical Study on Isatis TF Trifocal Intraocular Lens
The study will be a multicentric, prospective open-label ethics committee approved clinical study to investigate safety, visual outcomes, contrast sensitivity and rotational stability after bilateral implantation of Isatis TF IOL…
- Trial name
- NCT04465344
- Testing
- Implantation of trifocal IOL, Isatis TF (device under investigation), Implantation of monofocal IOL, Isatis (control device)
- Where
- 7 sites in Czechia, Spain
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Cutting Edge SAS
Lenses, Intraocular, Contrast Sensitivity
A Pilot Study Simulating Multifocal Intraocular Lenses in Healthy Subjects
Age related cataracts are responsible for about 51 percent of blindness worldwide and according to the WHO affect about 20 million people, according to the WH .
- Conditions
- Lenses, Intraocular, Contrast Sensitivity, Visual Acuity
- Trial name
- NCT01873781
- Testing
- Cyclopentolatehydrochloride
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Cataract
Safety and Effectiveness of a Multifocal Intraocular Lens (IOL)
To evaluate the safety and effectiveness of the ZM900 Tecnis Multifocal lens. Results from two studies (an original study with 125 multifocal and 123 monofocal subjects, protocol DIOL-101-TCNS, and an expansion study with 222…
- Trial name
- NCT00747565
- Testing
- Tecnis ZM900 Multifocal Intraocular Lens, CeeOn 911A monofocal IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Pseudophakia
Wavefront Analisys and Contrast Sensitivity of Spherical and Aspherical Intraocular Lenses
Purpose:To compare visual performance, total and high order wavefront aberrations (coma, spherical aberration and other terms) and contrast sensitivity in eyes implanted with one monofocal aspheric intraocular lens (IOL) and two…
- Trial name
- NCT00347243
- Testing
- phacoemulsification (cataract surgery)
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical