Clinical trials: Intraocular Lens Implant
Cataract, Corneal Astigmatism
A Prospective Clinical Investigation to Evaluate the Safety and Performance of 877PTY Toric IOL for Visual Correction of Corneal Astigmatism
Medicontur preloaded hydrophobic monofocal toric intraocular lenses (IOLs) are indicated to improve vision at far distance in adults with or without cataract and correction of pre-existing corneal astigmatism secondarily to…
- Trial name
- NCT06578884
- Testing
- 877PTY
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- Medicontur Medical Engineering Ltd
Aphakia
Comparison of Safety and Efficacy of Four-Point Scleral Intraocular Lens Fixation and Yamane Techniques
Comparison of safety and efficacy of two scleral fixation intraocular lens (IOL) methods of four-point scleral fixation ( Akreos AO60) and the Yamane technique (AcrySof MA60AC)
- Trial name
- NCT06389643
- Testing
- Four-point scleral fixation of Akreos AO60 IOL, Sutureless scleral fixation of AcrySof MA60AC IOL with Yamane technique
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Military Institute od Medicine National Research Institute
Cataract Surgeries
Comparison of the Concordance Between Digital Marking and Manual Marking for Toric Intraocular Lens Positioning
This cross-sectional comparative study evaluated patients from a single cataract center. In each eye, manual horizontal meridian axis line was marked on the cornea using the manual peripheral corneal marking technique (Horizontal…
- Trial name
- NCT07710963
- Testing
- Verion Digital Marking
- Volunteers
- 100 people
- Sponsor
- Thammasat University
Cataract, Age-related Cataract
Association Between Light Spectrum and Survival After Cataract Surgery
This study was a retrospective observational cohort analysis of subjects aged 65 years and older, who underwent bilateral cataract surgery within a single (15 hospital) healthcare system, to determine the association between type…
- Conditions
- Cataract, Age-related Cataract, Circadian Rhythm Disorders, Glaucoma
- Trial name
- NCT04187157
- Testing
- Blue-light filtering intraocular lens, Conventional intraocular lens
- Where
- United States
- Volunteers
- 10,192 people
- Sponsor
- University of Pittsburgh
Cataract
Evaluate the Safety and Effectiveness of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens
The objective of the study is to evaluate the safety and effectiveness of the enVista trifocal intraocular lens when implanted in the capsular bag.
- Trial name
- NCT03603600
- Testing
- enVista MX60E, enVista MX60EF
- Where
- 23 sites in United States
- Volunteers
- 501 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Refractive Errors
Comparison of Intraocular Lens Power Calculation Methods After Corneal Laser Refractive Surgery in Axial and Refractive Ammertropia
The study aims at determining the best biometry calculation formula to be used in IOL calculation of cataract patients how previously underwent laser refractive correction surgery
- Trial name
- NCT01979172
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- The National Eye Hospital, Cairo, Egypt
Cataract Senile
Evaluation of Glistening, Visual Outcomes and General Safety 24 Months Post-IOL Implantation
Main evaluation of glistening at least 24 Months post-IOL implantation
- Trial name
- NCT07297719
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA
This is a study to compare visual outcomes of subjects bilaterally implanted w/ReSTOR to subjects bilaterally implanted with the Tecnis Multifocal Intraocular Lens (IOL) or Acri.LISA IOL
- Trial name
- NCT00721253
- Testing
- ReSTOR, Tecnis, Acri.LISA
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataracts, Astigmatism
Investigation of Corneal Aberrations and Visual Outcomes in Patients Implanted With an AcrySof Toric Intraocular Lens (IOL)
A prospective evaluation of postoperative corneal aberrations and visual parameters (e.g. visual acuity) in patients implanted with an AcrySof Toric IOL.
- Trial name
- NCT00878839
- Testing
- Toric
- Sponsor
- Alcon Research
Cataract, Lens Opacities
Clinical Study to Compare Visual Performance of Two Trifocal IOLs
Prospective, randomised, controlled, single-surgeon, single-center post-market clinical follow up study to compare the clinical outcomes of two trifocal IOLs with different material
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- PHY1702 (NCT03347981)
- Testing
- IOL implantation experimental, IOL implantation active comparator
- Where
- Spain
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Lens Opacities
Comparison of ISOPURE and EYHANCE (Switzerland)
This is a prospective randomised open-label study with the aim to compare the visual performance of the premium monofocal Isopure IOL versus the extended depth of focus Eyhance® IOL after phaco-emulsification cataract surgery.
- Trial name
- PHY2301 (NCT05875922)
- Testing
- IOL implantation experimental (ISOPURE 1.2.3.), IOL implantation active comparator (TECNIS Eyhance)
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Visual Acuity
To Evaluate the Visual Performance After Bilateral Implantation of Multifocal Intraocular Lenses
To evaluate the visual performance after bilateral implantation of multifocal intraocular lenses.
- Trial name
- NCT03223857
- Testing
- Femtosecond-laser-assisted lens exchange
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Clinic Frankfurt
Cataract
Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens
Cataract surgery presents an extremely high success rate in improving vision and quality of life and it is currently the most commonly performed ophthalmic surgery, especially considering its growing utility in the aging…
- Trial name
- NCT06093880
- Testing
- monofocal intraocular lens
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- SIFI SpA
Cataract
Predicting Lens Tilt Using Optical Coherence Tomography and Partial Least Squares Regression Modelling
Misalignment of IOLs can cause severe loss of visual quality. Different types of misalignment are known. Tilt is one type of misalignment that is thought to play a negative role for the optical performance in eyes with IOL…
- Trial name
- Tilt (NCT05915429)
- Where
- Austria
- Volunteers
- 110 people
- Sponsor
- Johannes Kepler University of Linz
Aphakia, Mydriasis
Sutureless Intrascleral Intraocular Lens Fixation and Modified Iris Cerclage Pupilloplasty
In this study, patients with various causes of pupillary dilatation were recruited, and medical records and ophthalmology examinations, including slit-lamp examination, visual acuity, best corrected visual acuity, intraocular…
- Trial name
- NCT05829122
- Testing
- Sutureless Intrascleral Intraocular Lens Fixation and Modified Iris Cerclage Pupilloplasty
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Changzhou Second People's Hospital affiliated with Nanjing Medical University
Cataract
Functional Vision With ACRYSOF® IQ IOLs Blue Light Filtration
The purpose of this study is to compare the reaction time (as measured by braking reaction time in seconds during simulated driving) under glare and no-glare conditions in subjects implanted with ACRYSOF® IQ intraocular lenses…
- Trial name
- NCT02219997
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses, ACRYSOF® IQ IOL
- Volunteers
- 90 people
- Sponsor
- Alcon Research
Cataract
Prospective Clinical Study of Unilateral or Bilateral Implantation of Intraocular Lens in Cataract Patients
This is to evaluate the satisfaction of patient and postoperative functional vision of unilateral or bilateral Implantation of intraocular lens（IOLs） in cataract patients.
- Trial name
- NCT04265820
- Testing
- unilateral implantation of IOL, bilateral implantation of IOL
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Cataract
Vivity Study in Taiwan
The aim of study is to evaluate the quality of vision after bilateral Vivity or Vivity toric EDOF IOLs implantation in Taiwan.
- Trial name
- NCT06719882
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Taipei Nobel Eye Clinic
Cataract, Aphakia - Lens Capsule Present
Visual Adaptation and Quality of Life After Different IOL Implantation Strategies
This longitudinal observational study aims to evaluate long-term visual adaptation trajectories, optical quality, and patient-reported outcomes in age-related cataract patients following bilateral implantation of multifocal or…
- Trial name
- MMAQ-IOL (NCT07740590)
- Testing
- Bilateral Bifocal IOL Implantation, Bifocal and EDOF IOL Mix-and-Match Implantation, Bifocal and Monofocal IOL Mix-and-Match Implantation
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Sichuan Academy of Medical Sciences
Angle Closure Glaucoma
Laser Iridotomy Versus Phacoemulsification in Acute Angle Closure
This is a randomised controlled clinical trial to compare laser peripheral iridotomy (LPI) and primary phacoemulsification with intra-ocular lens implantation (phaco/IOL) in the treatment of acute primary angle-closure glaucoma…
- Trial name
- NCT00350428
- Testing
- Laser Preipheral Iridotomy and phacoemulsification
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- Singapore National Eye Centre