Clinical trials: Intraocular Lenses
Aphakia, Astigmatism
Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL)
The purpose of this Post-Market Clinical Follow-up (PMCF) study is to describe the long-term safety and performance of the AcrySof IQ PanOptix IOL toric and non-toric models in subjects bilaterally implanted with these IOLs for 3…
- Conditions
- Aphakia, Astigmatism, Presbyopia
- Trial name
- NCT06166901
- Testing
- AcrySof IQ PanOptix IOL Toric, AcrySof IQ PanOptix IOL Non-Toric
- Where
- 7 sites in Spain
- Volunteers
- 211 people
- Sponsor
- Alcon Research
Visual Acuity
Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence
The purpose of this study is to evaluate visual acuity in different lighting conditions (daylight and night time) and distances (distance, near and intermediate), and the independence of glasses, in patients who have had…
- Trial name
- NCT01191502
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Astigmatism, Cataract
Limbal Relaxing Incision Versus Toric Intraocular Lens for Corneal Astigmatism During Cataract Surgery.
This study will compare toric intra-ocular lens (IOL) with limbal relaxing incisions (LRI) in correcting astigmatism in patient undergoing standard cataract surgery.
- Trial name
- NCT02067429
- Testing
- Limbal Relaxing Incisions, Toric Intraocular Lens
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Christin Henein
Cataract
PMCF Study of Preloaded Trifocal IOL
This is a study to evaluate the safety, effectiveness and patient satisfaction of the Trifocal Intraocular Lens after implanted to replace the natural lens following cataract removal.
- Trial name
- NCT04884178
- Testing
- Trifocal Preloaded IOL Delivery System
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- ICARES Medicus, Inc.
Macular Holes, Epiretinal Membrane
Intraoperative OCT Guidance of Intraocular Surgery II
The overall five-year goals of the project are to develop novel technology to provide actionable new information through provision of live volumetric imaging during surgery, improving surgical practice and outcomes.
- Conditions
- Macular Holes, Epiretinal Membrane, Diabetic Retinopathy, Retinal Detachment
- Trial name
- MIOCT (NCT03713268)
- Testing
- Microscope integrated optical coherence tomography
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Duke University
Cataract
Clinical Results of Asqelio Trifocal Toric Diffractive Intraocular Lens
The goal of this observational prospective clinical study is to learn about the clinical outcomes three months after binocular implantation of Asqelio Trifocal Toric IOL in 30 patients submitted to cataract surgery following…
- Trial name
- NCT06190925
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AST Products, Inc.
Cataract Extraction
Exploratory Study of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction by Phacoemulsification.
This is an exploratory study to determine the safety and clinical benefit of OMS302 Injection in subjects undergoing Cataract Extraction with Lens Replacement (CELR) using a coaxial phacoemulsification process.
- Trial name
- NCT00721695
- Testing
- OMS302, OMS302-PE, Vehicle
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Omeros Corporation
High Myopia
Changes of the Corneal Endothelial Cell Count After Artisan Phakic Intraocular Lens Implantation
the investigator will evaluate the change in endothelial cell count in eyes implanted with the iris-claw phakic Artisan lens for treatment of moderate to high myopia using specular microscopy
- Trial name
- NCT03266354
- Testing
- specular microscopy before and after Artisan PIOL
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Assiut University
Aphakia
Evaluation of Clareon Vivity/Vivity Toric
This study seeks to generate clinical data from subjects previously implanted with the Clareon Vivity/Vivity Toric Intraocular Lenses (IOLs) or Clareon Monofocal/Clareon Toric IOLs.
- Trial name
- NCT05852470
- Testing
- Clareon Vivity/Vivity Toric Extended Vision IOL, Clareon Monofocal/Clareon Toric IOL
- Where
- 7 sites in United States
- Volunteers
- 155 people
- Sponsor
- Alcon Research
Age Related Cataracts
Evaluation of Physiological Responses at the Anterior Surface of Two (Hydrophobic Acrylic) Intraocular Lens Models
On the day of surgery, the the eye with astigmatism of at least 0.75dpt receives a Vivinex XY1A , HOYA Surgical Optics GmbH and the second eye to be operated receives an XY1, HOYA Surgical Optics GmbH.
- Trial name
- NCT04230629
- Testing
- Vivinex XY1, Vivinex XY1A
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Presbyopia, Refractive Errors
Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses
Primary objective of this study is to compare two presbyopia correction surgical techniques, specificaly premium monovision, in which the dominant eye is corrected with an extended depth of field intraocular lens and the…
- Conditions
- Presbyopia, Refractive Errors, Cataract
- Trial name
- NCT05494177
- Testing
- bUDVA, bUIRA, bUNRA, bUICPS, bUNCPS, Contrast sensitivity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Democritus University of Thrace
to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema
The Effect of a Blue Light Filtering IOL
To compare the effect on blood retinal barrier disruption 3 and 12 months after implantation of either a blue light filtering intraocular lens(blue-filtering IOL) or an ultraviolet light filtering intraocular lens(UV-filtering…
- Conditions
- to Compare the Effect of Two Types of IOLs, on the Incidence of Cystoid Macular Edema, After Cataract Surgery
- Trial name
- NCT00571831
- Testing
- intraocular lens implantation
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Showa University
Cataract
Post-Implant Performance of the EC-3 IOL
The purpose of this study is to obtain data on the performance of the EC-3 lens at an interval of two years (and beyond) from subjects who were implanted.
- Trial name
- NCT01333345
- Where
- 3 sites in United States, France
- Volunteers
- 100 people
- Sponsor
- Aaren Scientific Inc.
Cataract
A Clinical Investigation of MINIVISC® PLUS 14 mg/ml Fermented Ophthalmic Viscosurgical Device (OVD-F), Used for Cataract Surgery and Implantation of Intraocular Lenses, Glaucoma Surgery, Anterior Segment Surgery and Corneal Transplantation (CGAC)
A clinical investigation to confirm the clinical safety and performance of OVD-F device MINIVISC® PLUS 1.4 % for cataract surgery and implantation of intraocular lenses, glaucoma surgery, anterior segment surgery and corneal…
- Trial name
- Minivisc01 (NCT07184437)
- Testing
- OVD-F device Minivisc®PLUS 14 mg/ml
- Where
- 6 sites in Belgium, Sweden
- Volunteers
- 134 people
- Sponsor
- Bohus Biotech AB
Primary Open Angle Glaucoma, Pseudoexfoliative Glaucoma
Phacotrabeculotomy Versus CCI+Phaco in Patients With Borderline Control of Intraocular Pressure
The purpose of the study is to determine whether combined cataract and glaucoma surgery (phacotrabeculotomy)is more effective in lowering intraocular pressure than cataract surgery alone in patients with borderline control of…
- Trial name
- NCT00346931
- Testing
- Phacoemulsification, implantation of intraocular lens, Phacoemulsification, Implantation of IOL, trabeculotomy
- Volunteers
- 9 people
- Sponsor
- Medical University of Vienna
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia (Secondary) in Adults
This study will determine the safety and effectiveness of the Artisan Aphakia Lens when used as a secondary implant to correct aphakia in adults.
- Trial name
- NCT01547429
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 18 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Cataract
Comparison of a New EDOF-IOL With a Standard-EDOF-IOL
Comparison of the new extended depth of focus (EDOF) intraocular lens (IOL) ARTIS ACTIVE, which is designed as a twinset of IOLs, with the standard EDOF IOL AT Lara .
- Trial name
- NCT03921762
- Testing
- Cataract surgery with Artis Active IOLs, Cataract surgery with AT Lara IOLs
- Where
- Austria
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
VR-based Informed Consent, Cataract and Intraocular Lens Surgery
VR for Cataract Anxiety Lowering Management
Cataract is currently the leading cause of blindness globally, and surgery is the only effective treatment. With the advancement of medical technology, cataract surgery is usually performed under topical anesthesia, which means…
- Trial name
- VR-CALM (NCT07586280)
- Testing
- Virtual reality simulation of intraoperative audiovisual experience
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Cataract
Efficacy of Honan Balloon in Intraocular Pressure Reduction Before Phacoemulsification
-Does Honan balloon reduce intraocular pressure preoperatively?
- Trial name
- NCT00386438
- Testing
- Honan balloon application
- Where
- Thailand
- Sponsor
- Chulalongkorn University
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research