Clinical trials: Intraocular Pressure, open to volunteers
Intracranial Pressure Increase
Non-Invasive and Non-Contact Intracranial Pressure Waveform Recording Using Dynamic Video Ophthalmoscopy
This study will test the use of video ophthalmoscope to provide information about intracranial pressure without the use of invasive methods, anesthesia or contact with the eye.
- Trial name
- ICP Waveform (NCT04046523)
- Testing
- Video ophthalmoscope
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Intraocular Pressure
Effect of Raised End-Tidal pCo2 on Choroidal Volume
This study is to investigate the relationship between arterial carbon dioxide (CO2) concentration and vitreous pressure on the choroidal volume by integrated intraoperative OCT imaging under eye exams under anesthesia.
- Trial name
- NCT06275308
- Testing
- Ventilation manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Intraocular Pressure
External Influences Upon Ocular Homeostasis
Our experiments are designed to test the overall hypothesis that position-dependent or water-dependent intra-ocular pressure (IOP) spikes occur in humans, and that these challenge ocular homeostasis.
- Trial name
- NCT00338065
- Testing
- Postural change, Water drinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Glaucoma
Glaucoma Screening to Enhance At-Risk Californians' Health
The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and…
- Trial name
- G-SEARCH (NCT06854198)
- Testing
- Glaucoma screening with optical coherence tomography (OCT), color fundus photography, and tonometry, Educational Brochure
- Where
- 3 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Glaucoma, Hypertension
Know Your Pressures NYC
Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed "Know Your Pressures NYC" to conduct blood pressure (BP)/glaucoma screenings in adults age 40+ to identify undiagnosed and/or uncontrolled…
- Conditions
- Glaucoma, Hypertension, Glaucoma, Suspect, Elevated Blood Pressure
- Trial name
- NCT05992415
- Testing
- Virtual Automated Navigator Intervention with Health Education, Usual Care
- Where
- United States
- Volunteers
- 7,085 people, healthy volunteers welcome
- Sponsor
- Columbia University
Glaucoma
Functional and Structural Imaging for Glaucoma
The specific aims of the clinical studies are to: Develop a directional high-resolution OCT and OCT angiography prototype to improve imaging of structure and perfusion.
- Trial name
- FSOCT (NCT01957267)
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Intraocular Pressure
IOP Elevation Study
The purpose of this study is to improve understanding of the pathophysiologic process that leads to the development of glaucamotous damage.
- Trial name
- NCT03400137
- Testing
- Increasing of intraocular pressure (IC)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Glaucoma
Comparison of Intraocular Pressure Measurement With the Novel TonoVera Device With Other Commonly Used Devices
We are testing the accuracy of Reichert's Tono-Vera tonometer by comparing measurements of IOP with this device and measurements with other commonly-used tonometers, including Goldmann Applanation and iCare.
- Trial name
- NCT05523622
- Testing
- Tono-Vera tonometer, Goldman Applanation Tonometry
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Intraocular Pressure
Safety, Tolerability, and Accuracy of a Hydrogel-Based Wearable Dynamic Intraocular Pressure Sensor in Healthy Adults
The occurrence and progression of eye diseases like glaucoma are closely related to intraocular pressure fluctuations. Traditional single-point intraocular pressure measurement methods cannot reflect daily dynamic changes and are…
- Trial name
- NCT07770178
- Testing
- Hydrogel-Based Wearable Dynamic Intraocular Pressure Sensor
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Glaucoma
Efficacy and Safety of iStent in Reducing Intraocular Pressure in Open-angle Glaucoma
To evaluate the efficacy and safety of istent inject W in reducing intraocular pressure in Chinese adult patients with open-angle glaucoma complicated with cataract.
- Trial name
- NCT07354009
- Testing
- PHACO+PC-IOL+iStent, PHACO+PC-IOL
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intraocular Pressure (IOP), Healthy Adult
Eplerenone and IOP in Healthy Adults
The goal of this clinical trial is to determine whether eplerenone lowers eye pressure in healthy adults. Eplerenone is a medication approved by the U.S. Food and Drug Administration for other medical conditions.
- Trial name
- NCT07795762
- Testing
- Eplerenone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Keratoconus, Intraocular Pressure
Measuring the Changes of the Intraocular Pressure After Corneal Cross Linking Using Corvis CT
To evaluate the changes that occur in the intraocular pressure before and after corneal cross linking using Corvis CT.
- Trial name
- NCT07599020
- Testing
- Corvis Machine
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Tanta University
Glaucoma
Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery
The goal of this clinical trial is to determine if the intraoperative application of Mitomycin-C can enhance the outcomes of Ahmed Glaucoma Valve (AGV) implantation in treating refractory glaucoma.
- Trial name
- MMC (NCT06680245)
- Testing
- Mitomycin c
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Healthy Participants
The Effects of Strength Training Volume, Intensity, and Breathing Techniques on Intraocular Pressure and Retinal Blood Vessels
This study aims to determine the effects of different breathing patterns on ocular vasculature and intraocular pressure (IOP) during isokinetic and isometric strength exercises.
- Trial name
- NCT07326462
- Testing
- Normal Breathing, Valsalva maneuver
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Glaucoma
Smart Soft Contact Lenses for Monitoring Glaucoma
This study is exploring the effectiveness and safety of soft contact lenses with embedded sensors, called smart contact lenses. Smart contact lenses are used to measure the pressure inside the eye.
- Trial name
- NCT07224542
- Testing
- Bare Contact Lens, Experimental Smart Contact Lens, Commercially available smart contact lens
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Indiana University
Intraocular Pressure, Delivery
The Effect of Labor on Intraocular Pressure Fluctuation in Healthy Eyes
Glaucoma is a multifactorial disease, an important risk factor of which is increased intraocular pressure. Fluctuations in intraocular pressure are often associated with vaginal birth, although intraocular pressure during active…
- Trial name
- ELIPFHE (NCT06016712)
- Testing
- SENSIMED Triggerfish Eye Lenses
- Where
- Czechia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady