Clinical trials: Intraoperative
Inhalation Anesthesia, Dexmedetomidine
The Impact of a Single Dexmedetomidine Bolus on Intraoperative Sevoflurane Consumption (DEXHALE)
Sevoflurane is a volatile agent easy to control thanks to the Minimum Alveolar Concentration (MAC) allowing its titration for an optimal depth of anesthesia.
- Conditions
- Inhalation Anesthesia, Dexmedetomidine, Sevoflurane, Laparoscopy
- Trial name
- NCT05615194
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Post-operative Pain
Intraoperative TAP Block After Repeat Cesarean
The aim of this study is to perform a randomized trial to investigate if intraoperative surgeon administered TAP block reduces pain and use of oral and parenteral pain medications after repeat cesarean delivery.
- Trial name
- NCT05393908
- Testing
- TAP Block Group
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Postoperative Atrial Fibrillation
Prevention of Postop Atrial Fibrillation Through Intraoperative Inducibility of Atrial Fibrillation and Amiodarone Treatment
Patients undergoing first time cardiac surgery will undergo rapid atrial pacing prior to initiation of cardiopulmonary bypass to screen for AF inducibility.
- Trial name
- NCT03868150
- Testing
- Amiodarone Injection, Intraoperative Rapid Atrial Pacing
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stanford University
Burns, Hand Injuries
Range of Motion Following Intraoperative Coban Dressing Application in Hand Burns
Participants of this study will include burns requiring skin graft to hand(s). After informed consent, an occupational therapy evaluation will be performed.
- Trial name
- NCT01027520
- Testing
- application of coban dressing
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Anesthesia, Local
Comparison Between Efficiency of Inferior Alveolar Nerve Block and Buccal Infiltration Techniques Using Articaine 4% 1:100000
This split mouth randomized control trial is designed as to compare the effectiveness of the buccal infiltration technique with the gold standard inferior alveolar nerve block in anesthetizing mandibular second primary molars to…
- Trial name
- NCT03130855
- Testing
- inferior alveolar nerve block with 4% articaine, buccal infiltration with 4% articaine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hypotension (MeSH: D007022)
Carotid Artery Blood Flow, Blood Pressure, and Cardiac Output During Anesthesia in Children Aged 0-5 Years
Blood pressure is routinely monitored during anesthesia in children, but blood pressure alone may not accurately reflect blood flow to vital organs.
- Trial name
- CARFLOW (NCT07847203)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Anesthesia, Anesthesia Awareness
Pediatric Validation of CONOX Monitor During Surgery
Pediatric Validation of CONOX Monitoring device (qCON and qNOX indices) for anesthesia depth during surgery
- Conditions
- Anesthesia, Anesthesia Awareness, Nociceptive Pain, Pediatric ALL
- Trial name
- NCT04826146
- Testing
- Validation of qCON versus BIS
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Patricio Gonzalez Pizarro
Ossification Posterior Longitudinal Ligament, Cervical Spondylotic Myelopathy
Comparison of IONM Between Remimazolam and Propofol
Inhalation anesthetics significantly can delay latency and reduce amplitude of cortical MEPs and SSEPs signals compared to intravenous anesthetics by acting on not only GABA (γ-aminobutyric acid) receptors but also NMDA…
- Trial name
- NCT04968054
- Testing
- Arm I (Propofol), Arm II (Remimazolam)
- Where
- South Korea
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Stress
Intraoperative Pauses in Relation to Stress Assessment Among Surgeons
Intraoperative stress among the surgical team can be a threat to patient safety and good teamwork. During surgery, surgeons often work under stressful conditions.
- Trial name
- SAFT (NCT04626648)
- Testing
- Pause with a sugar containing drink
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Sahlgrenska University Hospital
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Surgical Blood Loss
Assessment of Hematologic Parameters Before and After Bimaxillary Orthognathic Surgery
The purpose of the present study was to compare some hematologic parameters and operation time in patients who underwent esthetic bimaxillary surgery under hypotensive anesthesia.
- Trial name
- NCT02364765
- Testing
- Remifentanil
- Where
- Brazil
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Thyroid Cancer, Thyroid Nodule
Modified Cormack Lehane Scores Evaluated by Laryngoscopy During Awake Versus Under General Anesthesia
Nowadays, 5-step modified Cormack-Lehane scoring (MCL) system is frequently used in the observation of laryngeal structures by direct laryngoscopy.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Adenoma
- Trial name
- NCT03826680
- Testing
- Flexible fiberoptic laryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Dexmedetomidine, Craniotomy
Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block vs Bupivacaine Alone for Hemodynamics Stability in Craniotomy
The investigator tested the effect of dexmedetomidine as an adjuvant to bupivacaine compared to bupivacaine alone in mean arterial pressure stability in adult patients undergoing craniotomy
- Conditions
- Dexmedetomidine, Craniotomy, Regional Anesthesia, Mean Arterial Pressure Stability
- Trial name
- NCT06951256
- Testing
- Scalp block with bupivacaine alone, Scalp block by adding dexmedetomidine as an adjuvant to bupivacaine
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Music and Anesthesia
The Effects of Instrumental Music on Intraoperative Parameters and Postoperative Pain and Side Effects
The clinical study started after receiving ethical approval from the Clinical Research Ethics Committee of Van Yüzüncü Yıl University and obtaining patient consent.
- Trial name
- NCT05886231
- Testing
- music sound therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Post Operative Pain
The Effect of Platelet Rich Plasma (PRP) on Post Operative Pain in Anterior Cruciate Ligament Reconstruction
The purpose of this research study is to investigate whether or not platelet rich plasma (PRP) may help to improve tendon healing and decrease post operative pain in patients undergoing anterior cruciate ligament (ACL)…
- Trial name
- NCT01765712
- Testing
- Anterior Cruciate ligament reconstruction bone patellar tendon bone autograft, Platelet Rich Plasma
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Brian Walters
Ultrasonography, Gastrointestinal Disease
Role of Intraoperative Ultrasound in Gastrointestinal (GI) Malignancies
Currently available investigating modalities like CT scans, MRI etc although have a high accuracy in staging of gastrointestinal(GI) tract malignancies, are not correct in all cases .
- Conditions
- Ultrasonography, Gastrointestinal Disease, Malignancy
- Trial name
- NCT01143922
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Bowel; Ischemic, Acute
FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery
This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia.
- Trial name
- FLAMES (NCT06322862)
- Testing
- Indocyanine green
- Where
- 5 sites in Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Prewarming, Holmium Laser Prostate Surgery
Comparison of the Effect of Prewarming on Intraoperative Hypothermia in Patients Undergoing Holmium Laser Prostatectomy
This study aims to evaluate the effectiveness of prewarming methods in preventing intraoperative hypothermia in patients undergoing HoLEP surgery.
- Conditions
- Prewarming, Holmium Laser Prostate Surgery, Hypothermia Following Anesthesia
- Trial name
- NCT06847659
- Testing
- intraoperative body temperature
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Ureteral Injury, Surgery--Complications
Ureteral Jets and Patient Positioning Study
The objective of the study is to identify the relationship between patient position during surgery and time to confirmation of ureteral patency on cystoscopy.
- Trial name
- NCT04732403
- Testing
- Patient Position
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Arizona