Clinical trials: Intraoperative Outcomes
Cesarean Delivery, Postpartum Hemorrhage (PPH)
Topical Tranexamic Acid to Reduce Blood Loss During Cesarean Delivery
The goal of this clinical trial is to learn whether applying topical tranexamic acid (TXA) directly to the uterine incision during cesarean delivery can reduce surgical bleeding compared to placebo.
- Conditions
- Cesarean Delivery, Postpartum Hemorrhage (PPH), Intraoperative Blood Loss, Hemostasis
- Trial name
- NCT07362992
- Testing
- Tranexamic Acid (Topical)
- Where
- 4 sites in Israel
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Intraoperative Outcomes, Postoperative Outcomes
Lateral Window Versus Intralift™ Sinus Floor Elevation
Several approaches have been used in order to regenerate bone in the upper jaw in case of insufficient alveolar bone height for implant placement.
- Trial name
- NCT04499625
- Testing
- Sinus floor elevation, Sinus floor elevation using an ultrasonic device
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Liege
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Postoperative Pain, Carpal Tunnel Release
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
The purpose of this study is to determine the efficacy of intra-operative administration of IV tylenol and/or IV toradol in minimizing post-operative pain for carpal tunnel patients and distal radius fracture patients.
- Conditions
- Postoperative Pain, Carpal Tunnel Release, Distal Radius Fracture
- Trial name
- NCT02313675
- Testing
- Acetaminophen, Ketorolac Tromethamine, Saline
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- John Fowler
Analgesia, Analgesia, Epidural
Postoperative Analgesia in Major Gynecological Cancer Surgeries
The aim of this study is to compare the effectiveness of epidural block or erector spinae plane block applied for postoperative analgesia in gynecological cancer surgeries.
- Conditions
- Analgesia, Analgesia, Epidural, ERAS
- Trial name
- NCT06424938
- Testing
- Patients who underwent epidural block, Patients who underwent erector spina plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Duygu Akyol
Pain, Postoperative
Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion
The following is a double blinded, randomized controlled clinical trial to test the hypothesis that a single epidural injection of Ropivaciane® intra operatively will:1) Single intra-operative epidural injection of Ropivaciane®…
- Trial name
- NCT03035656
- Testing
- Ropivacaine, Saline
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
Chronic Otitis Media Tympanic Membrane Perforation
Effect of Platelet-Rich Plasma on Eardrum Healing and Hearing After Tympanoplasty in Adults
This single-center controlled trial evaluated whether intraoperative application of autologous platelet-rich plasma (PRP)-impregnated absorbable gelatin sponge improves graft take rates and audiological outcomes in adults…
- Trial name
- NCT07664319
- Testing
- Autologous platelet-rich plasma (PRP)-impregnated Spongostan, Dry Spongostan (absorbable gelatin sponge)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ebubekir Toprak
Benign Prostatic Hyperplasia
Thulium Laser Versus Bipolar Enucleation of the Prostate
Comparing the peri-operative outcomes in patients with benign prostatic hyperplasia (BPH) who will undergo bipolar enucleation of the prostate versus thulium laser enucleation.
- Trial name
- NCT05200065
- Testing
- Thulium laser enucleation of the prostate, Bipolar enucleation of the prostate
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blood Loss, Surgical
Arista Hemostatic Powder for Total Knee Post Operative Outcomes Study
To examine in Arista hemostatic powder results in less post-total knee arthroplasty blood loss, hematoma formation, and improved range of motion when compared to patients who did not receive the product.
- Trial name
- NCT05522153
- Testing
- Arista
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Virtua Health, Inc.
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis
Prospective Clinical Study Evaluating Tibiofemoral Rotational Alignment Using Intraoperative Sensing During Total Knee Arthroplasty (TKA)
The objectives of the study are twofold: 1) Evaluate how intra-operative sensing may assist the surgeon with tibiofemoral rotational alignment by testing the precision and variability of setting tray rotation to the mid-third of…
- Trial name
- NCT02286739
- Testing
- TKA with "Verasense", TKA without "Verasense"
- Where
- 6 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Orthosensor, Inc.
Breast Cancer
Breast Cancer With Intraoperative Radiotherapy Followed by Hypofractionated External Beam Radiotherapy
To evaluate cosmetic outcomes after conservative surgery for breast cancer with INTRABEAM followed by hypofractionated external beam radiotherapy
- Trial name
- IORT_BREAST (NCT05498311)
- Testing
- Intraoperative Radiotherapy (IORT), Breast conservative surgery, External Beam Hypofractionated Radiotherapy (EBRT)
- Where
- Spain
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Institut Català d'Oncologia
Robotic Hysterectomy (Benign Indications/Early-stage Cancer)
Effect of Preoperative Simulator Warmup on Intraoperative Robotic Surgical Skills
Surgical residents and fellows acquire operative knowledge and skills by assisting attending surgeons in the operating room. Previous research has shown that practising technical skills prior to operating on patients can improve…
- Trial name
- NCT01969487
- Testing
- Preoperative warm-up on simulator
- Where
- 2 sites in United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Intraocular Lens Implantation, Cataract
Intraoperative Aberrometry vs Conventional Intraocular Lens Calculation, a Prospective Study.
the goal of this intervention study is to compare prospectively the accuracy of the power calculation between both groups, the intraoperative aberrometry (ORA) vs barrett universal II preoperative calculation (control group) .
- Conditions
- Intraocular Lens Implantation, Cataract, Humans, Ocular, Refraction
- Trial name
- ORAVSCTRL (NCT06219252)
- Testing
- Intraoperative aberrometer, Preoperative intraocular lens calculation
- Where
- Mexico
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Humans, Urinary Incontinence
Intraoperative Nerve Monitoring During Robotic-assisted Radical Prostatectomy
The purpose of this study is to evaluate whether the use of intraoperative nerve monitoring during robotic-assisted radical prostatectomy (RARP) can predict and improve post-surgery urinary continence and erectile function.
- Conditions
- Humans, Urinary Incontinence, Male Urogenital Diseases, Prostatectomy
- Trial name
- NCT03721029
- Testing
- Intraoperative nerve monitoring,, standard of care robotic-assisted radical prostatectomy
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Herlev and Gentofte Hospital
Rotator Cuff Tears, Hemorrhage, Surgical
Effect of Intravenous Tranexamic Acid on Visual Clarity During Shoulder Arthroscopy in the Beach Chair Position
Shoulder arthroscopy offers numerous advantages and has led to a continuous increase in procedural complexity. Adequate intraoperative visual clarity is essential for successful performance of the procedure and is primarily…
- Conditions
- Rotator Cuff Tears, Hemorrhage, Surgical, Shoulder Injuries
- Trial name
- NCT05397652
- Testing
- Tranexamic Acid Injectable Product
- Where
- Croatia
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Nikola Matejcic
Cataract
Outcomes of Phacoemulsification With Torsional Ultrasound
To determine the differences in intra-operative complications, surgical duration, fluid usage, corneal thickness and endothelium cell density in eyes undergoing microcoaxial phacoemulsification (MCP) either with Torsional or…
- Trial name
- NCT01010490
- Testing
- Torsional ultrasound (INFINITI, Alcon, USA), Longitudinal U/S (Infiniti system, Alcon, USA), Longitudinal U/S (LEGACY 20000, Alcon, USA)
- Where
- India
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Iladevi Cataract and IOL Research Center
Arthroscopic Shoulder Surgery, Intra-articular Debridement
Intra-Operative Corticosteroid Injection During Arthroscopic Shoulder Surgery
The purpose of this study is to assess the efficacy of intra-operative subacromial corticosteroid injections in patients undergoing arthroscopic shoulder surgery on quality of life scores and activity level when compared to a…
- Conditions
- Arthroscopic Shoulder Surgery, Intra-articular Debridement, Subacromial Decompression, Acromioplasty
- Trial name
- NCT02867904
- Testing
- Methylprednisolone (40 mg depomedrol, 1ml, injection), Marcaine (4ml 0.5%, injection)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Peter Chang
Periprosthetic Joint Infection
Intraoperative Microbial Contamination
This is a randomized, controlled study which aims to show whether iodine impregnated incisional foil (IobanTM) has a place in the prevention of prosthetic joint infection (PJI).
- Trial name
- ICON (NCT03139539)
- Testing
- Ioban
- Where
- 3 sites in Denmark
- Volunteers
- 1,661 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Cataract Senile, Endophthalmitis
Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus Levofloxacin
Comparative safety study of intracameral levofloxacin versus moxifloxacin for postoperative infection prophylaxis
- Conditions
- Cataract Senile, Endophthalmitis, Antibiotic Side Effect, Safety Issues
- Trial name
- NCT04403334
- Testing
- Levofloxacin Ophthalmic, Moxifloxacin Ophthalmic
- Where
- Philippines
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Peregrine Eye and Laser Institute