Clinical trials: Intraoperative Pain Control
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Post Operative Pain, Acute
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia
Pregabalin is a structural analogue of gamma amino butyric acid (GABA). It binds to presynaptic alpha-2-delta subunit of voltage gated calcium channels in the brain and the spinal cord.
- Trial name
- NCT05150795
- Testing
- Pregabalin 150mg, Fentanyl 100 micrograms ampoule
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia, Local
Comparison Between Efficiency of Inferior Alveolar Nerve Block and Buccal Infiltration Techniques Using Articaine 4% 1:100000
This split mouth randomized control trial is designed as to compare the effectiveness of the buccal infiltration technique with the gold standard inferior alveolar nerve block in anesthetizing mandibular second primary molars to…
- Trial name
- NCT03130855
- Testing
- inferior alveolar nerve block with 4% articaine, buccal infiltration with 4% articaine
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Cairo University
Perioperative Pain Management
The Efficacy of Music on Perioperative Pain Management
The goal of this clinical trial is to learn if intraoperative music stimulation works to alleviate perioperative pain in surgical patients undergoing general anesthesia.
- Trial name
- NCT06467747
- Testing
- Music, Mute
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taichung Tzu Chi Hospital
Analgesia, Obstetrical, Postpartum Hemorrhage
Prospective Effect of Intravenous Ketorolac on Opioid Use, EBL and Complications Following Cesarean Delivery
In this randomized, double-blind control trial to evaluate the effect of ketorolac given at the time of cord clamp has on estimated blood loss and postcesarean pain control.
- Conditions
- Analgesia, Obstetrical, Postpartum Hemorrhage, Opioid Use, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT02509312
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Endometriosis, Postoperative Pain
Intraoperative Clonidine for Postoperative Pain Management in Patients Undergoing Surgical Treatment for Endometriosis
The role of a single dose of intraoperative clonidine on postoperative opioid requirements, pain intensity and opioid-related side effects in patients undergoing surgical treatment for endometriosis remains scarcely explored.
- Conditions
- Endometriosis, Postoperative Pain, Pain, Acute, Pain, Acute Postoperative
- Trial name
- CLONIPAIN (NCT05560230)
- Testing
- Clonidine, Isotonic saline
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Collapse of Thoracic Vertebra, Collapse of Lumbar Vertebrae
Study of Dexmedetomidine in Spine Surgery
The investigators will conduct a prospective randomized double blind study comparing methadone plus methadone and intraoperative dexmedetomidine in multi-level spine surgery in two randomized groups.
- Trial name
- NCT01850017
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Superior Hypogastric Plexus Block
Intraoperative Superior Hypogastric Plexus Block For Pain Relief During Cesarean-Section
PURPOSE: to evaluate the efficacy of superior hypogastric plexus block for pain relief after cesarean section
- Trial name
- NCT03460093
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Cesarean Section, Intraoperative Blood Loss
Scalpel Versus Diathermy for Transverse Abdominal Incision in First Elective Caesarean Section
The objective of this study will be to compare two methods of skin incisions during the first caesarean section (CS), that is scalpel and diathermy, assessing differences in blood loss during incision, incisional time, total…
- Conditions
- Cesarean Section, Intraoperative Blood Loss, Postoperative Pain, Wound Heal
- Trial name
- NCT05905861
- Testing
- Skin incision with scalpel., Skin incision with a diathermy.
- Where
- Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
No Disease or Condition is Being Studied
ANI-Guided Fentanyl Infusion During Living Donor Liver Resections
Thу goal of this study was to learn whether intraoperative analgesia nociception monitoring (ANI) could be beneficial during intraoperative monitoring for patients undergoing living donor liver resections.
- Trial name
- NCT06619977
- Testing
- Analgesia nociception monitoring (ANI)
- Where
- Ukraine
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Bogomolets National Medical University
Operative Incision
Effect of Intraoperative Ankle Nerve Blocks on Postoperative Discharge in Patients Undergoing Orthopaedic Foot Surgery
Postoperative pain is an important clinical issue which negatively affects patient's satisfaction, delays discharge and repeated admission after discharge in orthopedic surgery.
- Trial name
- NCT03550677
- Testing
- general anesthesia, ankle block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Topical Heat Application for Intraoperative Abortion Pain Management
Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl
Paracervical blocks are routinely used in first trimester surgical abortions and are a proven method for decreasing procedural pain.
- Trial name
- HAPPE (NCT02536235)
- Testing
- heat
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Cesarean Section (MeSH: D002585), Anesthesia
Evaluation of Consciousness Depth (qCON) and Analgesia Depth (qNOX) Indices in General Anesthesia
Objective: This prospective, single-center, observational clinical study aims to evaluate changes in qCON (hypnotic depth), qNOX (nociception/analgesia depth), EMG, and other parameters in patients undergoing elective cesarean…
- Conditions
- Cesarean Section (MeSH: D002585), Anesthesia, Intraoperative Awareness, Analgesia
- Trial name
- NCT07887919
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Kudret Dogru
Cesarean Section Complications, Postpartum Hemorrhage
The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT03967171
- Testing
- before uterine incision oxytocin, after clamping the umbilical cord oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Distal Radius Fracture
Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
The study is designed to assess the use of intraoperative dexamethasone on postoperative analgesia and stiffness after open reduction and internal fixation of distal radius fractures.
- Trial name
- NCT04889547
- Testing
- Dexamethasone, No dexamethasone
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Post Operative Pain, Acute, Laparoscopic Appendectomy
Intraoperative Intravenous Lidocaine for Pain After Laparoscopic Appendectomy
This randomized, double-blind, placebo-controlled clinical trial evaluated whether intraoperative intravenous lidocaine infusion improves postoperative analgesia and recovery in patients undergoing laparoscopic appendectomy.
- Trial name
- LIDO-APP (NCT07678385)
- Testing
- Lidocaine (drug)
- Where
- Venezuela
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario de Caracas
Anesthesia
Magnesium for Shivering in Epidural Lidocaine Deliveries
Magnesium has been shown to decrease the shivering experienced from neuraxial anesthesia. This study aims to investigate whether magnesium decreases the shivering experienced in parturients undergoing labor epidural anesthesia…
- Trial name
- Mag-SHIELD (NCT03439358)
- Testing
- Magnesium Sulfate, Normal Saline
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Analgesia, Surgical Procedure, Unspecified
TLIP Block Versus Modified TLIP Block for Posterior Decompression and Stabilization Surgery
This study aimed to compare the analgesia effectivity of TLIP and modified TLIP block in Posterior Lumbar Decompression and Stabilization Surgery Perioperatively.
- Trial name
- NCT05104203
- Testing
- Thoracolumbar Interfascial Plane block, Modified Thorcolumbar Interfascial Plane block
- Where
- Indonesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia