Clinical trials: Intraoperative Ventilation
Mechanical Ventilation
The Effect of Intraoperative Ventilation Mode on Hemodynamics and Lung Dynamics
In this study, it was aimed to compare the effects of pressure-controlled volume-guaranteed ventilation (PCV-VG) and volume-controlled ventilation (VCV) on lung dynamics and hemodynamics in patients undergoing vertebral surgery…
- Trial name
- NCT05776589
- Testing
- The mechanical ventilation mode
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Izmir Ataturk Training and Research Hospital
Ventral Hernia, Abdominal Wall Defect
Intraoperative Biomechanics in Complex Abdominal Wall Reconstruction
Background: A detailed study of the biomechanical changes before and after abdominal wall reconstruction (AWR) has not been performed.
- Trial name
- NCT03296475
- Testing
- Abdominal Wall Closure Force (N).
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University College, London
Postoperative Pulmonary Complications (PPCs), Feasibility Studies
PROtective Ventilation With FLOW-Controlled Ventilation
The investigators want to investigate in patients undergoing robot-assisted laparoscopic surgery (a minimally invasive procedure) how applicable flow-controlled ventilation is, and whether it might also be safer than the current…
- Conditions
- Postoperative Pulmonary Complications (PPCs), Feasibility Studies, Pilot Study
- Trial name
- PROFLOW (NCT06703814)
- Testing
- Intraoperative flow-controlled ventilation strategy, Intraoperative pressure-controlled ventilation strategy
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen
Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists
Effect of Glucagon-like Peptide-1 Receptor Agonists (GLP-1 RA) on Gastric Emptying
This study aims to assess the effect of using Glucagon-like peptide-1 receptor agonists (GLP-1) receptor agonists on gastric emptying on surgical patients and whether specific guidelines need to be established for these patients.
- Conditions
- Gastric Emptying, Glucagon-Like Peptide-1 Receptor Agonists, Intermittent Fasting, Intraoperative Complication Due to Anesthesia
- Trial name
- NCT07140289
- Testing
- Ultrasound of gastric contents
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wael Saasouh, MD
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Intraoperative Lung Protective Ventilation
Intraoperative Lung Protective Ventilation in Czech Republic
This questionnaire-based study aims to evaluate the adherence to and current clinical practices regarding intraoperative lung-protective ventilation (IOLPV) among anesthesiologists in the Czech Republic.
- Trial name
- IOLPVCZ (NCT07282899)
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.
Brain Tumor
Effect of Breathing Circuits on Intraoperative Body Temperature
To evaluate differences in intraoperative body temperature between heated huimid breathing circuit and conventional breathing circuit
- Trial name
- BT (NCT01831843)
- Testing
- Group C, Group E, Group M
- Where
- South Korea
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Sleep Apnea, Obstructive Sleep Apnea
Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea
The aim of this study is to substantially reduce overall postoperative morbidity and mortality associated with obstructive sleep apnea.
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Postoperative Complications
- Trial name
- NCT03109418
- Testing
- Ketamine, Control
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Temperature Change, Body
Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients
Our goal is to evaluate the efficacy of the Westmed system vs the Bair Hugger Blanket.
- Trial name
- ANAPOD (NCT03896867)
- Testing
- Anapod™ Humi-Therm Heated Humidification System Breathing Circuit, Bair Hugger™ Warming Blanket
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Blood Loss, Surgical
Effect of Equal Ratio Ventilation on Blood Loss During Posterior Lumbar Interbody Fusion Surgery
Ventilator mode change was associated with decrease in blood loss during posterior lumbar interbody fusion (PLIF) due to decrease in the peak inspiratory pressure (PIP).
- Trial name
- NCT03030963
- Testing
- Equal ratio ventilation(ERV), I:E Ratio "1:2
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Gangnam Severance Hospital
Anesthesia, Mechanical Ventilation
VC-AF vs FCV in Obese Patients Undergoing Laparoscopic Surgery
Obesity adversely affects respiratory physiology by reducing lung volumes and compliance and increasing airway resistance and alveolar collapse.
- Conditions
- Anesthesia, Mechanical Ventilation, Obesity
- Trial name
- NCT07875530
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Respiratory Failure, Acute Respiratory Failure Requiring Reintubation
Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)
Intraoperative intravenous fluid management practice varies greatly between anesthesiologists. Postoperative fluid based weight gain is associated with major morbidity.
- Conditions
- Respiratory Failure, Acute Respiratory Failure Requiring Reintubation, Pulmonary Edema, Pneumonia
- Trial name
- NCT02105298
- Where
- United States
- Volunteers
- 104,000 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital