Clinical trials: Intraosseous Vascular Access
Proximal Humerus Interosseous Venous Access, Anatomic Landmark
Ultrasonographic Identification of the Proximal Humerus Landmarks
Evaluate whether discrete landmarks of the proximal humerus can be identified using ultrasound in patients with various body habitus and BMI.
- Conditions
- Proximal Humerus Interosseous Venous Access, Anatomic Landmark, Ultrasonography
- Trial name
- NCT03121794
- Testing
- Ultrasonographic exam, ultrasound machine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
Difficult Peripheral IV Access
Intraosseous Access in the Emergency Department for Patients With Failed Attempts at Intravenous Access: A Randomized Trial Examining Resource Utilization and Patient Satisfaction
By doing this study, the investigators hope to learn whether patients with difficult to obtain IV access who are treated with IO access are more satisfied with their care and have better outcomes.
- Trial name
- NCT01676350
- Testing
- IO access using EZ-IO®
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- WellSpan Health
Intraosseous Vascular Access, Vascular Access
Follow-Up Study Validating a Blended Technique to Identify the Proximal Humerus Intraosseous Vascular Access Site
A Follow-up Study Validating a Blended Technique for Identifying the Proximal Humerus Intraosseous Vascular Access Insertion Site
- Trial name
- NCT01866501
- Testing
- Intraosseous Vascular Access
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Intraosseous Vascular Access
Proximal Humerus Site for Anesthesia
This will be a prospective, non-controlled study using healthy adult volunteers as subjects receiving bilateral proximal humerus intraosseous (IO) vascular access to evaluate the insertion technique and IO infusion flow rates.
- Trial name
- NCT01866514
- Testing
- intraosseous vascular access in the proximal humerus, EZ-IO
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Stroke, Intracranial Hypotension
Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access
Hypertonic saline is used to treat elevated intracranial pressure. Intraosseous vascular access has been used to administer fluids and medications. This study combines these to administer 3% hypertonic saline via IO.
- Conditions
- Stroke, Intracranial Hypotension, Cerebral Edema
- Trial name
- NCT03276494
- Testing
- Intraosseous, Hypertonic saline
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Ohio State University
Patients Requiring Urgent Vascular Access
Observation of Intraosseous Vascular Access in the Emergency Department
The purpose of this study is to evaluate the use of powered intraosseous vascular access (EZ-IO by Vidacare) in the emergency department for patients requiring urgent vascular access.
- Trial name
- NCT01235078
- Testing
- EZ-IO
- Where
- 6 sites in United States
- Volunteers
- 105 people
- Sponsor
- Vidacare Corporation
Cardiac Arrest
Intravenous Vs. Intraosseous Vascular Access During Out-of-Hospital
The "Intravenous vs. Intraosseous Vascular Access During Out-of-Hospital Cardiac Arrest (IVIO)"-trial is an investigator-initiated, randomized, parallel group, patient and outcome assessor-blinded, superiority trial of…
- Trial name
- IVIO (NCT05205031)
- Testing
- Intraosseous access, Intravenous
- Where
- 5 sites in Denmark
- Volunteers
- 1,479 people
- Sponsor
- Lars Wiuff Andersen
Emergency Medical Service, Out-of-Hospital Cardiac Arrest
Venous Injection Compared To intraOsseous Injection During Resuscitation of Patients With Out-of-hospital Cardiac Arrest
Overall survival of patients after out-of-hospital cardiac arrest (*OHCA*) is less than 10% worldwide and in Taiwan. Interventions provided by the emergency medical system (*EMS*) before arrival at the hospital are of paramount…
- Conditions
- Emergency Medical Service, Out-of-Hospital Cardiac Arrest, Vascular Access, Intraosseous Access
- Trial name
- VICTOR (NCT04135547)
- Testing
- intra-osseous access vs. intra-venous access
- Where
- Taiwan
- Volunteers
- 1,732 people
- Sponsor
- National Taiwan University Hospital
Cardiac Arrest
Intraosseous Versus Intravenous Vascular Access During Cardiac Arrest
The objective of this study will be to compare humeral and tibial IO needle insertions to peripheral IV access during cardiac arrest.
- Trial name
- NCT01119807
- Testing
- Intravenous access during OHCA, Humeral IO insertion, TIbial IO insertion
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Wake Forest University Health Sciences
Intraosseous Vascular Access
Healthy Adult Volunteer Study of Intraosseous Infusion Using the Sternum
This study is being done to evaluate intraosseous vascular access through the sternum.
- Trial name
- NCT01853215
- Testing
- T.A.L.O.N. Intraosseous System
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
PR-0164 First in Human Clinical Trial of the PAVmed PortIO Intraosseous Infusion System
The PortIO is intended to provide non-emergent vascular access in chronic kidney disease (CKD) patients where preservation of venous anatomy is desired and iatrogenic damage to the veins should be avoided and/or patients with…
- Conditions
- Chronic Kidney Disease stage3, Chronic Kidney Disease stage4, Chronic Kidney Disease Stage 5, Poor Vascular Access
- Trial name
- NCT06037265
- Testing
- PAVmed PortIO™ Intraosseous Infusion System
- Where
- 4 sites in Colombia
- Volunteers
- 15 people
- Sponsor
- PAVmed Inc.
Patients With Intraosseous Vascular Access Requiring Computed Tomography (CT) Exam
Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route
An observational study to determine the safety and effectiveness of Intraosseous (IO) vascular access for delivery of contrast dye for Computed Tomography (CT) examination.
- Trial name
- NCT01531686
- Testing
- Intraosseous delivery of CT contrast dye
- Where
- 4 sites in United States
- Volunteers
- 8 people
- Sponsor
- Vidacare Corporation
Intraosseous Vascular Access
Continuous Intraosseous Vascular Access Over 48 Hours
A prospective study to determine the safety of intraosseous (IO) access for a period up to 48 hours in healthy adult volunteers and volunteers with a history of mild to moderate renal disease and/or controlled diabetes.
- Trial name
- NCT01866475
- Testing
- EZ-IO
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Airway Control
Rapid Sequence Intubation Drug Delivery Using Intraosseous and IV Access in Pediatric Patients Observational Study
This study will evaluate using intraosseous vascular access and intravenous vascular access to give pediatric patients the necessary medications to perform rapid sequence intubation, for patients with airway difficulties.
- Trial name
- NCT01634867
- Where
- United States
- Sponsor
- Vidacare Corporation
Airway Control
Observational Study of Rapid Sequence Intubation Drug Delivery Using Intraosseous and Intravenous Access.
This study will evaluate using intraosseous vascular access and intravenous vascular access to give patients the necessary medications to perform rapid sequence intubation, for patients with airway difficulties.
- Trial name
- NCT01486407
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Vidacare Corporation
Vascular Access
Evaluation of Various Methods Used to Identify the Proximal Humerus Intraosseous Vascular Access Site
The purpose of this study is to determine if there is one method of identifying the proximal humerus intraosseous vascular access site that is easier for clinicians to use, out of the 4 methods being evaluated.
- Trial name
- NCT01742780
- Testing
- Intraosseous Vascular Access
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation
Cardiac Arrest
Cardiac Arrest and Intra Osseous Infusion
the international recommendations don't explain the place of the intraosseous infusion in the reanimation of adult cardiac arrest; the goal of this preliminary study is to inform the delay for obtaining a vascular access by…
- Trial name
- ACCIO (NCT01803971)
- Testing
- Obtention of vascular access in out-of-hospital cardiac arrest patients according to the current strategy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Bordeaux
Catheters, Indwelling, Central Venous Line
EZIO Compared to Central Venous Lines for Emergency Vascular Access
Multicenter randomized study to compare powered intraosseous access to standard central line access for the administration of fluids and drugs for patients in the Emergency Dept.
- Conditions
- Catheters, Indwelling, Central Venous Line, Intraosseous Needle
- Trial name
- NCT00785252
- Testing
- Powered Intraosseous device (EZIO), standard central line
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Out-of-Hospital Cardiac Arrest
Intraosseous Versus Intravenous Vascular Access During Resuscitation Following Out-of-Hospital Cardiac Arrest
1. Background: Intraosseous (IO) access is a new, fast, safe and efficient route of rescue of critically ill patients. Studies found drug pharmacokinetics and pharmacodynamics of IO are similar to IV route.
- Trial name
- NCT04130984
- Testing
- EZ-IO
- Where
- China
- Volunteers
- 2,356 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intraosseous Access, Infusion Rates
Infusion Flow Rates and Blood Sampling
To evaluate infusion flow rates attainable when using the proximal humerus and proximal tibia IO vascular access sites. To evaluate the intraosseous infusion physiology when using the proximal humerus and proximal tibia IO…
- Conditions
- Intraosseous Access, Infusion Rates, Intraosseous Blood, Venous Blood
- Trial name
- NCT02021617
- Testing
- Intraosseous access
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vidacare Corporation