Clinical trials: Intraperitoneal Pressure
Acute Appendicitis, Acute Appendicitis With Rupture
Modified Enhanced Recovery Program in Emergency Surgery (MERES)
Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay.
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis With Peritonitis, Acute Appendicitis Without Peritonitis
- Trial name
- MERES (NCT03754777)
- Testing
- Laparoscopic appendectomy
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- Pirogov Russian National Research Medical University
Intracranial Pressure Increase, Abdominal Pain
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries
The aim of this study is to investigate the effects of low and normal intraperitoneal pressures on intraoperative optic nerve sheath diameter in laparoscopic gyneco-oncologic surgeries.
- Conditions
- Intracranial Pressure Increase, Abdominal Pain, Head Pain
- Trial name
- NCT07155109
- Testing
- Low pressure group, Normal pressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Uterine Prolapse
Laparoscopic Surgery in Elderly Patients
The primary purpose is to evaluate the quality of post-operative recovery and post-operative pain in elderly patients (more than 75 years) who undergo laparoscopic surgery for uterine prolapse.
- Trial name
- NCT03095716
- Testing
- laparoscopic surgery
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Clermont-Ferrand
Intraperitoneal Pressure, Peritoneal Dialysis
Novel Equation for Estimating Intraperitoneal Pressure
Intraperitoneal Pressure is associated with the complications of increased intra-abdominal pressure in peritoneal dialysis patients.
- Conditions
- Intraperitoneal Pressure, Peritoneal Dialysis, Equation
- Trial name
- NCT05313841
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Acute Cholecystitis, Gangrenous Cholecystitis
Enhanced Recovery in Laparoscopic Cholecystectomy
The study assesses the impact of the modified enhanced recovery protocol on the results of surgical treatment of patients with acute cholecystitis.
- Trial name
- ERLAC (NCT03754751)
- Testing
- Laparoscopic cholecystectomy with the implementation of modified ERAS program, Laparoscopic cholecystectomy with standard perioperative treatment
- Where
- Russia
- Volunteers
- 189 people
- Sponsor
- Pirogov Russian National Research Medical University
Pain, Inflammatory, Pain Management
Reduced-pressure Pneumoperitoneum and Intraperitoneal Saline Washout to Alleviate Pain Following vNOTES Hysterectomy
vNOTES, initially employed for cholecystectomy, appendectomy, and nephrectomy, made its debut in the field of gynecologic surgery in 2012.
- Trial name
- Vnotes (NCT06944015)
- Testing
- normal saline
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Pediatric Renal Failure
Intraperitoneal Pressure Measurements Survey in Pediatric Centers
Intraperitoneal pressure (IPP) is an objective measurement used to assess tolerance to fluid volume. IPP has been shown to be strongly correlated with intraperitoneal dialysate volume as well as anthropometric parameters.
- Trial name
- IPP (NCT07339709)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Gynecologic Disease
Different Maneuvers for Reducing Post-laparoscopic Pain
Laparoscopic surgeries are becoming more attractive because of early recovery. However, post-laparoscopic shoulder and upper abdominal pain may cause more discomfort to the patient than the pain at the incision site Many…
- Trial name
- NCT04475809
- Testing
- group C, Group L, Group LR
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Zagazig University
Postoperative Pain, vNOTES
Does Intraperitoneal Washout Further Reduce Pain After Low-Pressure vNOTES Hysterectomy?
The evolution of minimally invasive gynecology has transitioned from traditional laparotomy to laparoscopy, and most recently, to vNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery).
- Trial name
- Low-Pressure (NCT07467577)
- Testing
- warm saline
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Erzincan Military Hospital
Laparoscopic Hysteretctomy With Promontofixation
Impacts of Intraperitoneal Pressure and CO2 Gas on Surgical Peritoneal Environment
Use lay language. The primary purpose is to compare the impacts of intraperitoneal pressure (8mmHg versus 12 mmHg) and CO2 gas (cool, dry CO2 gas versus warmed, humidified CO2 gas) on gene expression in peritoneal tissues during…
- Trial name
- NCT01887028
- Testing
- Fisher and Paykel Humidifier (MR860AEU)
- Where
- France
- Volunteers
- 82 people
- Sponsor
- University Hospital, Clermont-Ferrand
Peritoneal Neoplasms, Echocardiography Guided Fluid Management
Comparison of Traditional and Echocardiography Guided Fluid Management During Cytoreductive Surgery With HIPEC
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is performed in patients with peritoneal tumors. Classically, this procedure is prolonged in duration and involves significant fluid shifts.
- Trial name
- NCT01225757
- Testing
- Echocardiogram
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Primary Study Outcome: Sodium Clearance in Dialysis, Solute Removal
Proof of Concept of Adapted PD in Children (PC-AAPD)
The purpose of this study is to validate the concept of adapted automated PD a modified Peritoneal Equilibration Test (PET), will be performed in children on chronic PD.
- Conditions
- Primary Study Outcome: Sodium Clearance in Dialysis, Solute Removal, Ultrafiltration
- Trial name
- PC-AAPD (NCT02748733)
- Testing
- Adapted double mini PET, Standard double mini PET
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Heidelberg University
Peritoneal Dialysis
Intraperitoneal Pressure Measurements in Children
Pediatric peritoneal dialysis is prescribed according to the type of dialysis, the volume infused and the dialysis time. The measurement of intraperitoneal pressure (IPP) is an important and easy indicator to perform.
- Trial name
- IPM (NCT05149508)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Strasbourg, France
Peritoneal Dialysis, Kidney Failure, Chronic
Relating Abdominal Complications With Peritoneal Pressure Estimation and Reporting
This is a prospective observational study in people treated with peritoneal dialysis for kidney failure to investigate whether estimated intraperitoneal pressure (eIPP) is correlated with non-infectious PD-related complications…
- Conditions
- Peritoneal Dialysis, Kidney Failure, Chronic, Hernia, Abdominal
- Trial name
- RAPPER (NCT06060951)
- Testing
- Estimated intraperitoneal pressure
- Where
- 2 sites in United Kingdom
- Volunteers
- 300 people
- Sponsor
- Imperial College Healthcare NHS Trust
Recurrent Ovarian Cancer
Intraperitoneal Aerosol High-pressure Chemotherapy for Women With Recurrent Ovarian Cancer
This trial aims to assess efficacy and safety of an intraperitoneal, aerosol, high-pressure chemotherapy in women with recurrent ovarian cancer
- Trial name
- NCT01809379
- Testing
- chemotherapy with doxorubicin and cisplatin
- Where
- Germany
- Volunteers
- 69 people
- Sponsor
- Ruhr University of Bochum