Clinical trials: Intrarenal Pressure
Kidney Stones
Comparison of Smart Pressure-Controlled Flexible Ureteroscopy and Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy for 2-3 cm Renal Stones
This prospective, multicenter, randomized, non-inferiority controlled trial aims to compare the efficacy and safety of smart pressure-controlled flexible ureteroscopy and flexible ureteroscopy assisted by a distal flexible…
- Trial name
- NCT07909577
- Testing
- Smart Pressure-Controlled Flexible Ureteroscopy, Distal Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy
- Volunteers
- 750 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urolithiasis, Calcium Oxalate, Ureteroscopy
Clinical Trial of VISOR vs fURS for Upper Urinary Tract Stone
This prospective randomized controlled clinical study aims to evaluate the safety and efficacy of a novel Vortex Intelligence Stone Optimized Removal (VISOR,The experimental group) system compared to a single-use ureterorenoscope…
- Conditions
- Urolithiasis, Calcium Oxalate, Ureteroscopy, Therapeutic Irrigation, Intraoperative Complications
- Trial name
- VISOR (NCT07181759)
- Testing
- VISOR, fURS
- Volunteers
- 100 people
- Sponsor
- Ningbo No. 1 Hospital
Urolithiasis
The Effect of Different Body Positions and Channel Sheaths on RIRS
Retrograde flexible ureteroscopy (RIRS) is currently the first-line treatment for renal stones < 2cm. Lower pole renal stones(LPS) are a difficult problem for urologists.
- Trial name
- NCT06438497
- Testing
- RIRS with f-UAS, lateral position, RIRS with f-UAS, lithotomy position, RIRS with traditional UAS, lateral position
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Nephrolithiasis, Kidney Calculi
Ureteral Access Strategies in Retrograde Intrarenal Surgery
Retrograde intrarenal surgery (RIRS) is a standard minimally invasive treatment for kidney stones up to 20 mm. During the procedure, irrigation fluid raises the pressure inside the kidney and laser energy raises the fluid…
- Conditions
- Nephrolithiasis, Kidney Calculi, Retrograde Intrarenal Surgery, Flexible Ureteroscopy
- Trial name
- NCT07898020
- Testing
- Flexible and navigable suction ureteral access sheath, Conventional ureteral access sheath, Sheathless flexible ureteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 129 people
- Sponsor
- Ondokuz Mayıs University
Renal Stone Disease
Intrarenal Pressure Monitoring During Pediatric Percutaneous Nephrolithotomy, and Its Impact on Post Operative Infectious Complications.
Monitoring of intrarenal pressure during pediatric percutaneous nephrolithotomy and its impact on post operative infectious complications.
- Trial name
- NCT07800546
- Testing
- Intrarenal pressure
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Nephrolithiasis
Intrarenal Pressure in Suctioning vs. Non-suctioning Sheaths
Interest in monitoring intrarenal pressure (IRP) during flexible ureteroscopy (fURS) has grown, especially due to its potential association with improved postoperative efficiency and safety.
- Trial name
- NCT07619456
- Testing
- Suctioning-UAS, Non-suctioning-UAS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Urolithiasis, Intrarenal Pressure
Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging Study
Introduction and objectives Saline irrigation and instrumentation during Retrograde Intrarenal Surgery (RIRS) causes elevation of intrarenal pressure (IRP) inducing intrarenal backflow (IRB).
- Conditions
- Urolithiasis, Intrarenal Pressure, MRI Scans, Scintigraphy Quantification
- Trial name
- BackFlow2 (NCT07913178)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Region of Southern Denmark
Kidney Stone
RIRS With Tip Flexible Pressure-controlling Ureteral Access Sheath Versus Mini PCNLfor Kidney Stones
The goal of this observational study is to compare the safety and efficacy between RIRS with tip flexible pressure-controlling ureteral access sheath and mini percutaneous nephrolithotripsy（PCNL） for the treatment of 2-3-cm…
- Trial name
- NCT06209931
- Testing
- RIRS
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Urinary Tract Infections, Ureteric Injury
Safety and Efficacy of Different Irrigation System in Retrograde Intrarenal Surgery
Urolithiasis is one of the most prevalent urological diseases affecting general population across the world. The available treatment modalities for renal stones are Shock wave lithotripsy (SWL), Percutaneous Nephrolithotomy…
- Conditions
- Urinary Tract Infections, Ureteric Injury, Sepsis
- Trial name
- RIRS (NCT05018546)
- Testing
- Irrigation force
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Kidney Stone, Unexplained Haematuria
Pharmacological Modulation of the Intrarenal Pressure During Endourological Procedures in the Upper Urinary Tract
The purpose of the study is to examine the effect of endoluminally administrated isoproterenol on pelvic pressure increase during flexible ureterorenoscopy in 14 humans.
- Conditions
- Kidney Stone, Unexplained Haematuria, Benignant Tumour Mass in the Upper Urinary Tract
- Trial name
- NCT00428428
- Testing
- Isoproterenol
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Fredericia Hosptial
Kidney Stone, Nephrolithiasis
Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of Surgeon Behavior and Post-operative Outcomes
The goal of this study is to evaluate the influence of real-time intrarenal pressure measurement availability on surgeons' behavior during ureteroscopy while using the ureteroscope LithoVue Elite.
- Trial name
- ELITE (NCT06576661)
- Testing
- INTRARENAL PRESSURE MONITORING VISIBLE
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Kidney Stone, Ureteroscopy
Retrograde Intrarenal Stone Surgery - A Method of Treating the ESWL Resistant Kidney Stone
Is it possible to decrease the intrarenal pressure in the kidney during endoscopic management of kidney stone by topical administration of drugs? In order to secure fewer complications in ureteroscopic operations the…
- Trial name
- NCT00323843
- Testing
- Isoproterenol
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Fredericia Hosptial
Kidney Stone
Intrarenal Pressure Monitoring Via Flexible and Navigable Suction Ureteral Access Sheath in Retrograde Intrarenal Surgery
This study evaluates the use of a novel intrarenal pressure (IRP)-monitoring flexible and navigable suction ureteral access sheath (FANS) in retrograde intrarenal surgery (RIRS) for renal stones.
- Trial name
- NCT06729801
- Testing
- IRP-Monitoring Flexible and Navigable Suction Ureteral Access Sheath (FANS), Conventional FANS
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stones, Nephrolithiasis
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney stones are a common health problem and may recur frequently, which can affect quality of life and kidney function. Retrograde intrarenal surgery (RIRS) is a minimally invasive treatment used for renal stones, but treatment…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07516535
- Testing
- Direct In-Scope Suction, Flexible and Navigable Suction Ureteric Access Sheath
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Ain Shams University
Optic Nerve Cup, Intracranial Pressure Increase
Effect of Lithotomy Position on Optic Nerve Sheath Diameter
In this study, the effect of increased venous return and increased intra-abdominal pressure on intracranial pressure in the lithotomy position was evaluated.
- Trial name
- NCT06464419
- Testing
- ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Hypertension
Febuxostat, Blood Pressure and the Intrarenal Renin-Angiotensin System (RAS)
In this study the investigators will recruit hypertensive subjects with higher than average uric acid levels to test the effect of lowering uric acid with febuxostat on several measures as listed below.
- Trial name
- NCT01328769
- Testing
- Febuxostat
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Paul N. Hopkins