Clinical trials: Intrathecal Dexmedetomidine
Pain Management in Adult Females in Child Bearing Period Aging From 20 to 45 Years Who Are Scheduled for Elective Cesarean Section
Intrathecal Dexmedetomidine Versus Transversus Abdominus Plane Block (TAP) for Postoperative Analgesia After Cesarean Section.
Spinal anesthesia is the most commonly used technique for lower abdominal surgeries as it is very economical and easy to administer.
- Trial name
- NCT04969705
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Nausea and Vomiting, Postoperative
Impact of Intrathecal vs Intravenous Dexmedetomidine
The purpose of this research is to evaluate the impact of intrathecal dexmedetomidine in comparison with intravenous route in patients undergoing cesarean section.
- Trial name
- NCT06410365
- Testing
- Dexmedetomidine injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muhammad Ilyas
Spinal Anesthesia, Postoperative Complications
D-FAB-POUR Trial: Dexmedetomidine vs Fentanyl as Adjuvants to Bupivacaine on Postoperative Urinary Retention
This study aims to compare two medications, dexmedetomidine and fentanyl, when used alongside a commonly used spinal anesthetic called bupivacaine in patients undergoing lower limb surgery.
- Conditions
- Spinal Anesthesia, Postoperative Complications, Dexmedetomidine, Fentanyl
- Trial name
- D-FAB-POUR (NCT07117565)
- Testing
- Intervention 1: Intrathecal Dexmedetomidine with Bupivacaine, Intervention 2: Intrathecal Fentanyl with Bupivacaine
- Where
- Nepal
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Post Operative Pain
Effects of Intrathecal Dexmedetomidine as an Adjuvant to Low Dose Hyperbaric 0.5% Bupivacaine
Patients will be enrolled in one of the two groups using a computer-generated random number table: Group I will receive 1.5 ml of 0.5% hyperbaric bupivacaine (7.5 mg).
- Trial name
- NCT05993975
- Testing
- Bupivacain 0.5%, Dexmedetomidine Hydrochloride
- Where
- Pakistan
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Dexmedetomidine, Transurethral Resection of Prostate
Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
This study is to evaluate The analgesic effect of intrathecal versus intravenous dexmeditomedine in transurethral resection of the prostate
- Conditions
- Dexmedetomidine, Transurethral Resection of Prostate, Intravenous, Intrathecal
- Trial name
- NCT04618965
- Testing
- control group, Intrathecal dexmedetomidine, Intravenous dexmedetomidine
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tanta University
Postoperative Pain, Pain
Comparison of Analgesic Efficacy of Intrathecal Bupivacaine Versus Bupivacaine Plus Dexmedetomidine in Patients Undergoing Orthopedic Surgeries.
Clinical Trial Overview: Intrathecal Bupivacaine vs. Bupivacaine + Dexmedetomidine Primary Objective Duration of Analgesia:** To compare the mean duration of postoperative pain relief between hyperbaric bupivacaine alone versus…
- Conditions
- Postoperative Pain, Pain, Orthopaedic Surgery, Anesthesia, Spinal
- Trial name
- NCT07866508
- Testing
- Dexmedetomidine plus Hyperbaric Bupivacaine, Hyperbaric bupivacaine % 0.5
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sheikh Khalifa Bin Zayed Al Nahyan Combined Military Hospital Muzaffarabad
Post-Op Complication
Comparison of Intrathecal Dexmedetomidine Versus Fentanyl as Adjuvants to Bupivacaine on Post-operative Urinary Retention in Knee Joint Arthroscopic Surgeries
The aim of this study was to assess the effect of intrathecally injected 5 µg dexmedetomidine or 25 µg fentanyl as adjuvants to bupivacaine in low dose spinal anesthesia for unilateral arthroscopic knee surgeries, on…
- Trial name
- NCT05596552
- Testing
- hyperbaric bupivacaine and dexmedetomidine, Bupivacaine-Fentanyl group
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Anesthesia Evaluation
The Prolonging Effect of Dexmedetomidine on Spinal Anesthesia Through Different Routes if Administrations
This prospective, double-blinded, randomized clinical trial aims to examine the effects of combining isobaric bupivacaine with dexmedetomidine administered intrathecally (IT), compared to the combination of isobaric bupivacaine…
- Trial name
- NCT06769737
- Testing
- Interventional group#1, Interventional group#2
- Where
- Saudi Arabia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Shivering, Spinal Anesthesia
Prevention of Shivering Associated With Spinal Anesthesia
The aim of the study is to compare the effectiveness of prophylactic use of intravenous (IV) dexmedetomidine VS ketamine and meperidine(as a control group) in prevention of shivering associated with intrathecal anesthesia in…
- Trial name
- NCT06082076
- Testing
- Dexmedetomidine, Ketamine, Meperidine
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anesthesia, Spinal
Intrathecal Dexmedetomidine With Bupivacaine for Spinal Anesthesia in Cesarean Section
A Randomized, Controlled, Double blind study aiming to evaluate the analgesic potentials and side effect profile of different dose levels of Dexmedetomidine added to subarachnoid bupivacaine in full-term pregnant women undergoing…
- Trial name
- NCT02365857
- Testing
- Dexmedetomidine & Bupivacaine., Bupivacaine Only.
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dexmedetomidine
Bupivacaine Alone vs Bupivacaine and Dexmed in Cesarean Deliveries
The purpose of the study is to compare the onset and duration of sensory and motor block after spinal anesthesia between intrathecal bupivacaine alone vs intrathecal bupivacaine and dexmedetomidine combination.
- Trial name
- NCT05469529
- Testing
- Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- KRL Hospital, Islamabad
Post Spinal Shivering
Dexmedetomidine in Spinal Anesthesia Decreasing Post Spinal Shivering in Caesarean Section
The investigators will test the effects of intrathecal dexmedetomidine as adjuvant to intrathecal bupivacaine and it's direct effect in decreasing incidence of post spinal shivering in Parturients Undergoing Caesarean section
- Trial name
- NCT06318546
- Testing
- Dexmedetomidine Injection [Precedex],,,, Fentanyl
- Where
- Egypt
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vaginal Delivery, Normal Labor
Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and…
- Trial name
- SSSA (NCT06823349)
- Testing
- Dexmedetomidine, fentanyl, Saline 0.9%
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Jehan George Sadek
Intrathecal Morphine, Intrathecal Morphine-dexmedetomidine Combination
Intrathecal Morphine Versus Morphine-dexmedetomidine Combination for Postoperative Pain Control After Total Knee Replacement
Total knee replacement is one of the most painful orthopedic surgical procedures. Patients who undergo total knee replacement are usually older and have limited cardiac and pulmonary reserves.
- Conditions
- Intrathecal Morphine, Intrathecal Morphine-dexmedetomidine Combination, Postoperative Pain Control, Total Knee Replacement
- Trial name
- NCT05439564
- Testing
- Dexmedetomidine, Morphine
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tanta University
Transurethral Resection of Prostate
Effect of Two Different Doses of Intrathecal Dexmedetomidine as Adjuvant in Elderly Patients Undergoing HoLEP
Transurethral resection of the prostate (TURP) is the most common Surgical intervention for elderly patients with benign prostatic hyperplasia.
- Trial name
- NCT05351489
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cesarean Section
Dexmedetomidine Versus Magnesium Sulphate for Caesarean Delivery
Regional anesthesia has become more popular in cesarean deliveries because most of the parturients prefer being awake during the birth process. In addition, regional anesthesia may be a safer method than general.
- Trial name
- NCT03067896
- Testing
- Bupivacaine, Dexmedetomidine, Magnesium Sulfate
- Where
- Egypt
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bone Fracture
A Comparative Study Between Intrathecal Dexmedetomidine VS Ketamine With Intrathecal Bupivacaine in Orthopedic Lower Limb Surgeries.
Orthopedic anaesthesia and acute postoperative pain management, two anesthesiology subspecialties,are getting more credit for reducing hospital stays, promoting functional recovery and improving patient satisfaction.
- Trial name
- NCT05751304
- Testing
- Dexmedetomidine, Ketamine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Intrathecal Dexmedetomidine
Intrathecal Dexmedetomidine to Decrease Postoperative Nausea and Vomiting and Shivering.
Background: Highly selective α-2 agonist dexmedetomidine in increasingly used as an intrathecal adjuvant for caesarean section performed under subarachnoid block.
- Trial name
- NCT05892705
- Testing
- Dexmedetomidine Injection [Precedex]
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain
Intrathecal Dexmedetomidine vs Midazolame
Prospective Randomized Controlled Clinical Trial to Compare Intrathecal Dexmedetomidine Versus Midazolame in Orthopedic Cancer Surgeries
- Trial name
- NCT06315634
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Cesarean Section Complications
Intrathecal Bupivacaine-fentanyl and Bupivacaine-dexmedetomidine for Elective Low Segment Caesarean Section
the primary objective of the study is to compare the onset and recovery times of sensory and motor blockade of the two study drugs intrathecally with low dose bupivacaine The secondary objectives of the study are to observe…
- Trial name
- NCT04095013
- Testing
- Bupivacaine, fentanyl, Bupivacaine, dexmedetomidine
- Where
- 2 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences